ER+ HER2- metastatic breast cancer

People with metastatic breast cancer are asked to participate in a research study being conducted by Montefiore Medical Center.

You may be eligible to participate in this study if you:
• Are at least 18 years of age
• Have histologically or cytologically confirmed locally advanced or metastatic breast cancer
• Have any unresolved toxicities from prior therapy
• Have not have received prior oral endocrine therapy

You may NOT participate in this study if you:
• Have a prior or concurrent malignancy
• Have known impaired cardiac function or clinically significant cardiac disease
• Have known immunodeficiency virus (HIV) infection
• Have a history of cerebral vascular disease or liver disease
• Have an active infection
• Have a history of leptomeningeal disease or spinal cord compression
• Have an active brain metastases
• Are pregnant or breastfeeding

Contact Information
Ana Bernal Guarin, Study Coordinator
111 E. 210th Street Bronx, NY 10467
Phone: (718) 798-5687
Email: abernal@montefiore.org

DESTINY-Breast06 Metastatic Breast Cancer

People with metastatic breast cancer are asked to participate in a research study being conducted by Montefiore Medical Center.

You may be eligible to participate in this study if you:
• Are a male or female at least 18 years of age
• Have pathologically documented breast cancer
• Have adequate tumor tissue, organ function, and bone marrow
• Have radiological evidence of disease progression
• Have had no prior chemotherapy for advanced or metastatic breast cancer

You may NOT participate in this study if you:
• Have received prior treatment with anti-HER2 therapy
• Have uncontrolled hypertension
• Have known immunodeficiency virus (HIV) infection, hepatitis B, or hepatitis C
• Are pregnant or breastfeeding

Contact Information
Kathy Lora, Study Coordinator
1695 Eastchester Road
Bronx, NY 10461
Phone: (718) 405-8523
Email: klora@montefiore.org