People with advanced or metastatic solid tumors are asked to participate in a research study being conducted by Montefiore Medical Center.

You may be eligible to participate in this study if you:

• Are at least ≥ 18 years of age
• Are histologically or cytologically diagnosed with locally advanced or metastatic BrCa,endometrial cancer and OvCa
• Have at least 1 measurable lesion
• Have adequate bone marrow function
• Have adequate liver and renal function

You may not participate in this study if you:

• Have any other active malignancy within 3 years
• Have advanced/metastatic, symptomatic, visceral spread, that are at risk of life-threatening complications
• Have clinically important hypertension
• Had major surgery within 3 weeks
• Have received systemic anti-cancer therapy or endocrine therapy within 4 weeks
• Have received radiation therapy within 3 weeks prior to first dose
• Have active, uncontrolled bacterial, fungal, or viral infection including COVID-19
• Are known to be positive for human immunodeficiency virus (HIV), hepatitis B, or C
• Are pregnant, breast feeding or planning to become pregnant

Contact Information
Gunnar Lauer, Study Coordinator
Phone: (718) 405-8124