Advanced or Metastatic Urothelial Carcinoma (PRESERVE 3)

People with metastatic urothelial carcinoma are asked to participate in a research study being conducted by Montefiore Medical Center.

You may be eligible to participate in this study if you:

• Are a male or female at least 18 years of age
• Have histologically documented, locally advanced (T4b, any N; or any T, N 2-3) or metastatic urothelial carcinoma
• Have had no prior systemic therapy
• Have adequate organ function
• Have provision of a recent tumor tissue block

You may NOT participate in this study if you:

• Have malignancies other than urothelial carcinoma
• Have a presence of central nervous system (CNS) metastases/leptomeningeal disease
• Have uncontrolled ischemic heart disease or uncontrolled symptomatic congestive heart failure
• Have known immunodeficiency virus (HIV) infection, hepatitis B, or C
• Have had a major surgical procedure, open biopsy, or significant traumatic injury within 4 weeks
• Have received a live, attenuated vaccine within 4 weeks
• Are pregnant or breastfeeding

Contact Information
Mary Portes, Study Coordinator
1695 Eastchester Road Bronx, NY 10461
Phone: (718) 405-8209