Metastatic Solid Tumors CRESTONE

People with Metastatic Solid Tumors are asked to participate in a research study being conducted by Montefiore Medical Center.

You may be eligible to participate in this study if you:

  • Are a male or female at least 18 years of age
  • Have locally-advanced or metastatic solid tumor with an NRG1 gene fusion
  • Adequate hepatic function & hematologic status
  • Have availability of fresh or archived FFPE tumor sample
  • Have at least one measurable extra-cranial lesion

You may NOT participate in this study if you:

  • Have received investigational treatment in another clinical study within the past 28 days
  • Have symptomatic or untreated brain metastases
  • Have known, actionable oncogenic driver mutation other than NRG1 fusion, where available standard therapy is indicated
  • Have an active uncontrolled systemic infection
  • Have clinically significant cardiac disease
  • Have known immunodeficiency virus (HIV) infection
  • Are pregnant or breastfeeding

Contact Information
Cristal Garcia, Regulatory Coordinator
1695 Eastchester Road – Bronx, NY 10461
Phone: (718) 405-8404
Fax: (718) 405-8433
Email:crigarci@montefiore.org