Non-Small Cell Lung Cancer PRA – Mirati – Krystal Program – 849-007

People with Non-Small Cell Lung Cancer are asked to participate in a research study being conducted by Montefiore Medical Center.

You may be eligible to participate in this study if you:
• Are a male or female at least 18 years of age
• Have unresectable or metastatic disease
• Histologically confirmed diagnosis of NSCLC (squamous or nonsquamous) with KRAS G12C mutation and known PD-L1 Tumor Proportion Score (TPS) score

You may NOT participate in this study if you:
• Have received prior systemic treatment for locally advanced or metastatic NSCLC
• Major surgery within 4 weeks prior to first dose of study treatment
• Have active brain metastases.
• History of stroke or transient ischemic attack
• Have an active or prior documented autoimmune or inflammatory disease
• Have known immunodeficiency virus (HIV) infection, hepatitis B, or hepatitis C
• Are pregnant or breastfeeding

Contact Information
Cristal Garcia, Regulatory Coordinator
Department of Medical Oncology
Montefiore Medical Center
1695 Eastchester Road – Bronx, NY 10461
Phone: (718) 405-8477
Fax: (718) 405-8230