Pyruvate Kinase Agonist in Patients with Sickle Cell Disease
People with Sickle Cell Disease are asked to participate in a research study being conducted by Montefiore Medical Center.
You may be eligible to participate in this study if you:
• Are a male or female aged 12 to 65 years
• Have had at least 2 episodes of VOC in the past 12 months
• Have a confirmed diagnosis of sickle cell disease
You may NOT participate in this study if you:
• Have had more than 10 VOCs
• Have hepatic dysfunction or severe renal dysfunction
• Have clinically significant bacterial, fungal, parasitic, or viral infection
• Have known immunodeficiency virus (HIV) infection, hepatitis B or C
• Have a history of unstable or deteriorating cardiac or pulmonary disease
• Are pregnant or breastfeeding
Contact Information
Karen Ireland, Study Coordinator
111 E. 210th Street Bronx, NY 10467
Phone: 718) 741-2050
Email: kireland@montefiore.org
21-10-176