Refractory Gastrointestinal Tract Tumors- EPON-PRIME

People with Advanced, Refractory Gastrointestinal Tract Tumors are asked to participate in a research study being conducted by Montefiore Medical Center.

You may be eligible to participate in this study if you:

  • Are a male or female at least 18 years of age
  • Have advanced, metastatic or unresectable GI tract tumors that are refractory or intolerant to existing available therapies
  • Have adequate bone marrow, liver, and renal function
  • Have not received treatment with IV 5-FU or oral 5-FU analogs in the 4 weeks
  • Hepatitis C or B infection and received antiviral treatment, has a negative viral load at Screening
  • The HIV infection, it is controlled with undetectable viral load with antiretroviral treatment

You may NOT participate in this study if you:

  • Have current brain metastasis
  • Have other clinically significant cardiac disease
  • Have had major surgery, open biopsy, or significant traumatic injury within 4 weeks
  • Have other primary cancer requiring treatment within the last 3 years
  • Have congenital long QT syndrome or a family history of long QT syndrome
  • Have a history or presence of clinically significant abnormal 12-lead ECG
  • Are pregnant or lactating

Contact Information
Mohammad Ghalib, Study Coordinator
1695 Eastchester Road, 2nd Floor
Bronx, New York 10461
Phone: (718) 405-8515