COSTAR Lung 213410 Prior Anti-Pd-(L)1 Therapy with Platinum Chemotherapy

People with Non-Small Cell Lung Cancer are asked to participate in a GlaxoSmithKline research study being conducted by White Plains Hospital.

You may be eligible to participate in this study if you:
• Are a male or female ≥18 years of age
• Have histologically or cytologically proven advanced or metastatic NSCLC
• Have received no more than 2 prior lines of therapy
• Have adequate organ function

You may NOT participate in this study if you:
• Have received investigational treatment in another clinical study within the past 4 weeks
• Have received radiation to the lung in the last 6 months
• Have known immunodeficiency virus (HIV) infection, hepatitis B or C
• Have current interstitial lung disease, current pneumonitis,
• Have received a live vaccine in the last 30 days
• Are pregnant or breastfeeding

Contact Information
Hyemin Kim, Study Coordinator
2 Longview Avenue
White Plains, New York 10601
Phone: (914) 849-7591
Email: hkim3@wphospital.org

Advanced Solid Tumors with KRAS G12C Mutation

People with Advanced Solid Tumors with KRAS G12C Mutation are asked to participate in a research study being conducted by Monter Cancer Center.

You may be eligible to participate in this study if you:
• Are a male or female at least 18 years of age
• Have histologically confirmed diagnosis of a solid tumor malignancy
• Have presence of tumor lesions

You may NOT participate in this study if you:
• Have active brain metastases
• Have undergone major surgery within 4 weeks of first dose date
• Have carcinomatous meningitis
• Have a history of stroke or transient ischemic attack
• Have known immunodeficiency virus (HIV) infection, hepatitis B, or C
• Are pregnant or breastfeeding

Contact Information
Alexa Amoroso, Study Coordinator
450 Lakeville Road, Lake Success, NY 11042
Phone: (516) 734-8977
Email: AAMOROSO1@NORTHWELL.EDU

TALAZOPARIB SOFT GEL CAPSULE FORMULATION Advanced Solid Tumors

People with Advanced Solid Tumors are asked to participate in a research study being conducted by Montefiore Medical Center.

You may be eligible to participate in this study if you:
• Are a male or female between the ages of 18 and 70
• Have histological diagnosis of recurrent, locally advanced or metastatic solid tumor
• Have adequate bone marrow, renal, and hepatic function
• Are able to swallow capsules whole without breaking apart or crushing

You may NOT participate in this study if you:
• Have had major surgery within the past 4 weeks
• Have been diagnosed with MDS or AML
• Have an active infection
• Have known or suspected brain metastasis or active leptomeningeal disease
• Have clinically significant cardiovascular disease
• Have known history of testing positive for HIV, AIDS, positive HBV surface antigen, positive HCV RNA, or positive COVID-19 viral test
• Are pregnant or breastfeeding

Contact Information
Mohammad Ghalib, Study Coordinator
1695 Eastchester Road, 2nd floor
Bronx, NY 10461
Phone: (718) 405-8515
Email: mhghalib@montefiore.org

Solid Tumors with KRAS p.G12C Mutation

People with Solid Tumor are asked to participate in a research study being conducted by Montefiore Medical Center.

You may be eligible to participate in this study if you:
• Are a male or female at least 18 years of age
• Are willing to provide tumor tissue samples
• Have the ability to take oral medications
• Pathologically documented, locally-advanced or metastatic malignancy with KRAS

You may NOT participate in this study if you:
• Have a history of malignancy within the past 2 years
• Have an active infection requiring IV antibiotics
• Have gastrointestinal tract disease causing inability to take oral medications
• Have known immunodeficiency virus (HIV) infection, hepatitis B, or hepatitis C
• Are pregnant or breastfeeding

Contact Information
Mohammad Ghalib, Study Coordinator
1695 Eastchester Road, 2nd floor
Bronx, NY 10461
Phone: (718) 405-8515
Email: mhghalib@montefiore.org

Sym021 in Combination with Either Sym022 or Sym023 in Patients with Advanced Solid Tumor Malignancies

People with Advanced Solid Tumor Malignancies are asked to participate in a research study being conducted by Montefiore Medical Center.

You may be eligible to participate in this study if you:

• Are a male or female at least 18 years of age
• Have documented (histologically or cytologically proven) unresectable, locally advanced or metastatic malignancies
• Have adequate organ function

You may NOT participate in this study if you:

• Have Central Nervous System unless treated and stable malignancies
• Have a significant cardiovascular disease, recent gastrointestinal disease, or pulmonary disease
• Have a history of organ transplant
• Have known immunodeficiency virus (HIV) infection, hepatitis B, or hepatitis C
• Are pregnant or breastfeeding

Contact Information
Mohammad Ghalib, Study Coordinator
1695 Eastchester Road, 2nd floor
Bronx, NY 10461
Phone: (718) 405-8515
Email: MHGHALIB@MONTEFIORE.ORG

Metastatic Solid Tumors

People with Metastatic Solid Tumors are asked to participate in a research study being conducted by Montefiore Medical Center.

You may be eligible to participate in this study if you:

• Are a male or female at least 18 years of age
• Have a histologically or cytologically documented, advanced (metastatic and/or unresectable) cancer
• Demonstrate adequate organ function

You may NOT participate in this study if you:

• Have received treatment with systemic anticancer treatments or investigational products (IPs) within 14 days before the first dose of study drug
• Have a history of uncontrolled brain metastasis
• Have had prior treatment with TAK-981
• Have a receipt of any live vaccine
• Have an active infection
• Have known immunodeficiency virus (HIV) infection, hepatitis B or C
• Are pregnant or breastfeeding

Contact Information
Mohammad Ghalib, Study Coordinator
1695 Eastchester Road, 2nd floor
Bronx, NY 10461
Phone: (718) 405-8515
Email: mhghalib@montefiore.org

Advanced and Recurrent Solid Tumors

People with solid tumors are asked to participate in a research study being conducted by Montefiore Medical Center.

You may be eligible to participate in this study if you:

  • Are a male or female at least 18 years of age
  • Have advanced or metastatic solid tumors and have completed first line therapy.
  • Evidence of disease progression
  • Adequate organ function

You may NOT participate in this study if you:

  • Have received chemotherapy within 28 days of the start of study
  • Have an active infection
  • Have known immunodeficiency virus (HIV) infection, hepatitis B, or hepatitis C
  • Are pregnant or breastfeeding

Contact Information
Cristal Garcia, Study Coordinator
1695 Eastchester Rd. Bronx, NY 10461
Phone: (718)- 405-8477
Email: crigarci@montefiore.org

Biomarker Study on Tumor Tissue for Non-small Cell Lung Cancer (NSCLC)

People with non-small cell lung cancer are asked to participate in a research study being conducted by Montefiore Medical Center

You may be eligible to participate in this study if you:

  • Are a male or female at least 18 years of age or older
  • Have pathologically documented, locally-advanced and unresectable or metastatic NSCLC
  • Have archived tumor tissue samples collected within 5 years

You may NOT participate in this study if you:

  • Have known additional malignancy other than NSCLC within last 3 years
  • Have known significant cardiovascular disease
  • Have known history of Human Immunodeficiency Virus (HIV) Infection, Hepatitis B and Hepatitis C

Contact Information
Cristal Garcia, Regulatory Coordinator
1695 Eastchester Road – Bronx, NY 10461
Phone: (718) 405-8404
Fax: (718) 405-8433
Email:   crigarci@montefiore.org

Advanced EGFR-positive Solid Tumor Malignancies

People with tumors are asked to participate in a research study being conducted by Montefiore Medical Center.

You may be eligible to participate in this study if you:

  • Are a male or female at least 18 years of age
  • Have a confirmed solid tumor
  • Have archival tumor tissue available

You may NOT participate in this study if you:

  • Have received major surgery within the past 4 weeks
  • Have cardiovascular disease
  • Have significant infections
  • Have known immunodeficiency virus (HIV) infection, hepatitis B, or hepatitis C
  • Are pregnant or breastfeeding

Contact Information

Imran Chaudhary, Study Coordinator
1695 Eastchester Road, Bronx, NY 10461
Phone: (718)- 405-8542
Email: ichaudha@montefiore.org

Stage III Non-Small Cell Lung Cancer (NSCLC)

People with non-small cell lung cancer are asked to participate in a research study being conducted by Montefiore Medical Center.

You may be eligible to participate in this study if you:

  • Are a male or female at least 18 years of age
  • Have confirmed NSCLC
  • Have adequate organ function
  • Have no evidence of metastatic disease

You may NOT participate in this study if you:

  • Have received investigational treatment in another clinical study within the past 4 weeks or had major surgery within the past 4 weeks
  • Have known history of tuberculosis
  • Have known immunodeficiency virus (HIV) infection, Hepatitis B, or Hepatitis C
  • Are pregnant or breastfeeding

Contact Information
Cristal Garcia, Study Coordinator
1695 Eastchester Road – Bronx, NY 10461
Phone: (718) 405-8477
Fax: (718) 405-8230
Email: crigarci@montefiore.org

Advanced Solid Tumors and Pancreatic Cancer

People with advanced solid tumors and pancreatic cancer are asked to participate in a research study being conducted by Northwell Health

You may be eligible to participate in this study if you:

  • Are a male or female at least 18 years of age or older
  • Have histologically confirmed advanced bladder cancer, melanoma, non-small cell lung cancer, pancreatic cancer, colorectal cancer, gastric cancer, esophageal cancer, ovarian cancer, and head neck squamous cell carcinoma

You may not participate in this study if you:

  • Are using a pacemaker, implantable cardiac defibrillator or cochlear implants
  • Have tested positive for Human Immunodeficiency Virus (HIV) Infection
  • Are pregnant, breastfeeding or plan to become pregnant

Contact Information
Sarah Davis, Phase 1 Supervisor
450 Lakeville Road, Lake Success, NY  11042
Phone: (516) 734-7632
Fax: (516) 734-8909
Email: sdavis22@northwell.edu

JAVELIN IL-2 Medley

People with solid tumors are asked to participate in a research study being conducted by Montefiore Medical Center.

You may be eligible to participate in this study if you:

  • Are a male or female at least 18 years of age or older
  • Have histological diagnosis of solid tumors

You may not participate in this study if you:

  • Have known history of: immune-mediated colitis, inflammatory bowel disease, pneumonitis, or pulmonary fibrosis.
  • Have had a live vaccine within the past 4 weeks
  • Have history of immunodeficiency virus (HIV) infection, hepatitis B or hepatitis C
  • Are pregnant or breastfeeding

Contact Information

Imran Chaudhary, Study Coordinator
1695 Eastchester Road, 2st Floor
Bronx, NY 10461
Phone: (718) 405-8542
Fax: (718) 405-8527
Email: ichaudha@montefiore.org
19-06-256 / TX228658

IIT-Uterine Serous Carcinoma

People with uterine serous carcinoma are asked to participate in a research study being conducted by Northwell Health Inc.

You may be eligible to participate in this study if you:

  • Are a female at least 18 years of age or older
  • Have histologically diagnosis of uterine serous carcinoma

You may not participate in this study if you:

  • Have had major surgery within the past 3 weeks
  • Have known active hepatitis disease
  • Are pregnant or breastfeeding

Contact Information

Mary Agnes Templeton, Study Coordinator
450 Lakeville Road
Lake Success, New York 11042
Phone: (516) 734-8979
Email: mtempleton@northwell.edu

 

19-06-278 / TX228668

Advanced Solid Tumors

People with solid tumors are asked to participate in a research study being conducted by Montefiore Medical Center.

You may be eligible to participate in this study if you:

  • Are a male or female at least 18 years of age or older
  • Have confirmed locally-advanced (unresectable) or metastatic solid tumor malignancy

You may not participate in this study if you:

  • Have received a live vaccine within the past 28 days
  • Have an active autoimmune disease
  • Have positive Hepatitis B virus antibodies and surface antigen (indicating acute HBV or chronic HBV) or Hepatitis C
  • Are pregnant or breastfeeding

Contact Information

Mohammad Ghalib, Study Coordinator
1695 Eastchester Road, 2nd Floor
Bronx, New York 10461
Phone: (718) 405-8515
Email: mhghalib@montefiore.org

19-06-134 / TX226742

Advanced Solid Tumors

People with advanced solid tumors are asked to participate in a research study being conducted by Northwell Health.

You may be eligible to participate in this study if you:

  • Are a male or female at least 18 years of age or older
  • Have histologic or cytologic confirmation of advanced solid tumor with the exception of ocular melanoma and hepatocellular carcinoma
  • Have received and have progressed on or be refractory to at least 1 line of standard systemic therapy in the recurrent/metastatic setting

You may not participate in this study if you:

  • Have moderate or severe cardiovascular disease
  • Have had major surgery within the past 4 weeks
  • Have known immunodeficiency virus (HIV) infection, active hepatitis B or hepatitis C
  • Are pregnant, breastfeeding or plan to become pregnant

Contact Information

Sarah Davis, Research Manager
450 Lakeville Road
Lake Success, NY 11042
Phone: 516-734-7632
Email:  sdavis22@northwell.edu

 

19-06-090 / TX226751

FIGHT-101 – Advanced Malignancies

People with advanced malignancies are asked to participate in a research study being conducted by Northwell Health.

You may be eligible to participate in this study if you:

  • Are a male or female at least 18 years of age or older
  • Have any advanced solid tumor malignancy
  • Have moderate renal impairment and severe renal impairment

You may not participate in this study if you:

  • Have had treatment with another investigational study drug or receipt of anticancer medications within the past 28 days
  • Have history of human immunodeficiency virus infection, hepatitis B or hepatitis C
  • Have active autoimmune disease requiring systemic immunosuppression in excess of physiologic maintenance doses of corticosteroids
  • Are pregnant, breastfeeding or plan to become pregnant

Contact Information
Sarah Davis, Study Coordinator
450 Lakeville Road
Lake Success, New York 11042
Phone: 516- 734-7632
Email: sdavis22@northwell.edu

Advanced Solid Tumors

People with Advanced Solid Tumors are asked to participate in a research study being conducted by Montefiore Medical Center.

You may be eligible to participate in this study if you:

  • Are a least 18 years of age
  • Have a diagnosis of melanoma or non small cell lung cancer

You may not participate in this study if you:

  • Have known uncontrolled central nervous system (CNS) metastases and/or carcinomatous meningitis
  • Have a known additional malignancy that progressed or required active treatment within the last 2 years
  • Have a known history of human immunodeficiency virus (HIV) infection or HIV 1/2 antibodies
  • Have a history of interstitial lung disease
  • Are pregnant or breastfeeding

Contact Information

Elizabeth Paljevic, Study Coordinator

1521 Jarrett Place, 2nd Floor

Bronx, NY 10461

Phone: (718) 862-8840 Ext.443

Email: elpaljev@montefiore.org

Advanced or Metastatic Solid Tumors

People with solid tumors are asked to participate in a research study being conducted by Montefiore Medical Center

You may be eligible to participate in this study if you:
• Are at least 18 years old
• Have malignancies in the advanced or metastatic stage
• Are able to swallow whole capsules
• Have the willingness and ability to comply with all protocol-specified requirements

You may not participate in this study if you:
• Have received chemotherapy, biologic therapy, immunotherapy or any other investigational agent within the past 3 weeks
• Have a known hypersensitivity to any temozolomide component or to dacarbazine (DTIC)
• Have had any major surgical procedure, open biopsy or traumatic injury within the past 4 weeks
• Have an active infection requiring systemic treatment
• Are pregnant, breastfeeding or plan to become pregnant

Contact Information

Mohammad Ghalib, Study Coordinator

1695 Eastchester Road

Bronx New York, 10461

Phone:  (718) 405.8515

Email: mhghalib@montefiore.org

Solid Tumors

People with solid tumors are asked to participate in a research study being conducted by Icahn School of Medicine at Mount Sinai

You may be eligible to participate in this study if you:

  • Are at least 18 years old
  • Have malignancies in the advanced or metastatic stage
  • Are able to swallow whole capsules
  • Have the willingness and ability to comply with all protocol-specified requirements

You may not participate in this study if you:

  •  Have received chemotherapy, biologic therapy, immunotherapy or any other investigational agent within the past 3 weeks
  • Have a known hypersensitivity to any temozolomide component or to dacarbazine (DTIC)
  • Have had any major surgical procedure, open biopsy or traumatic injury within the past 4 weeks
  • Have an active infection requiring systemic treatment
  • Are pregnant, breastfeeding or plan to become pregnant

Contact Information

Jean Hum, Study Coordinator

17 East 102nd Street

New York, New York 10029

Phone: (212) 824-7312

Email: jean.hum@mssm.edu

Advanced Malignancies

People with Advanced Malignancies are asked to participate in a research study being conducted by Montefiore Medical Center.

You may be eligible to participate in this study if you:

  • Are male or female and are at least 18 years old
  • Have confirmed solid tumors or lymphoma

You may not participate in this study if you:

  • Have had extensive radiotherapy within the past two years
  • Are HIV positive Have had any major surgery within the past month 
  • Are a female and are currently lactating or pregnant
  • Have Hepatitis B or C
  • Have any allergies to the study drug

Contact Information

Elizabeth Paljevic, Study Coordinator

111 E. 210th Street Bronx, NY 10467

Phone (718) 862-8840 Ext. 443

Email: elpaljev@montefiore.org