Virtual Pooled Registry Cancer Linkage System/BRANY Central IRB

BRANY IRB is contracted with National Cancer Institute (NCI) to serve as a Central IRB to review Virtual Pooled Registry – Cancer Linkage System (VPR–CLS) studies. The Common Rule requires use of a Central (or single) IRB for cooperative research.  Reliance on a Central IRB can eliminate redundancy and provide a consistent, high quality, expert review process that protects privacy and confidentiality while saving time and resources. 

To streamline the Central IRB application and review process for VPR-CLS studies, the North American Association of Central Cancer Registries (NAACCR) has developed a Templated IRB/Registry Application (TIRA -common form). BRANY IRB will perform their review using the TIRA and other supporting documents submitted with the VPR-CLS request.

The flow diagram below outlines the process for submitting to NAACCR and BRANY IRB.  

 

 

VPR-CLS Central IRB Submission Guidelines

 

 

 

Recent Presentations

 

  • Request for User Access - After you receive your initial approval, and would like access to IRBManager, please send a completed Request for User Access Form by email to Laura Donohue (or call 516-622-2049)
  • IRBManager™ Demonstration Webinar
    • Check the box to request a demonstration on the Request for User Access form
    • Email rhart@brany.com

Reporting Timelines

UPIRTSOS (Unanticipated Problems) Report per occurrence within 5 days
Serious Adverse Events (Local) Report per occurrence within 5 days
Unanticipated Adverse Device Events (UADEs) Report per occurrence within 10 days
Complaints Report per occurrence within 5 days
Major Deviations Report per occurrence within 10 days
Minor Deviations Report in aggregate with continuing review or study closure