T3011 oncolytic virus (OV) in patients with solid tumors

People with Metastatic Solid Tumors are asked to participate in a research study being conducted by Montefiore Medical Center.

You may be eligible to participate in this study if you:

  • Are a male or female at least 18 years of age
  • Have disease progression after SOC therapy
  • Have adequate hepatic & renal function

You may NOT participate in this study if you:

  • Have prior treatment with another OV or cellular therapy
  • Have untreated and/or symptomatic metastatic central nervous system (CNS) disease
  • Have splenectomy, previous allogenic tissue/solid organ transplant
  • Have known immunodeficiency virus (HIV) infection, hepatitis B or C
  • Have live vaccines within 4 weeks of initiation of study treatment. (Seasonal flu or
  • SARS-CoV-2 vaccines that do not contain live viruses are permitted.)
  • Are pregnant or breastfeeding

Contact Information
Mohammad Ghalib, Research Manager
1695 Eastchester Road, 2nd floor
Bronx, NY 10461
Phone: (718) 405-8515
Email: mhghalib@montefiore.org

 

Advanced Solid Tumor – Orinove – Clinipace

People with Advanced Solid Tumors are asked to participate in a research study being conducted by Monter Cancer Center.

You may be eligible to participate in this study if you:

  • Are a male or female at least 18 years of age
  • Have adequate organ function
  • Have adequate tissue sample
  • Are a male subject, you must be surgically sterile or must agree to use physician approved contraception

You may NOT participate in this study if you:

  • Have greater than Class II heart failure
  • Have an active malignancy
  • Have known active uncontrolled or symptomatic brain metastases
  • Have known immunodeficiency virus (HIV) infection, hepatitis B or C
  • Have any serious uncontrolled medical or psychological disorder
  • Are pregnant or breastfeeding

Contact Information
Amandeep Singh, Study Coordinator
450 Lakeville Road Lake Sucess, NY 11042
Phone: (516) 734-3587
Email: asingh73@northwell.edu

Metastatic squamous or nonsquamous NSCLC-KEYNOTE A86

People with Non-Small-Cell Lung Cancer are asked to participate in a research study being conducted by Montefiore Medical Center.

You may be eligible to participate in this study if you:

  • Are a male or female at least 18 years of age
  • Have histologically or cytologically confirmed diagnosis of squamous or nonsquamous NSCLC
  • Have not received prior systemic treatment for metastatic NSCLC
  • Have adequate organ function
  • Submit an archival tumor tissue sample

You may NOT participate in this study if you:

  • Have a known additional malignancy
  • Have an active infection
  • Have a known central nervous system metastases
  • Have known immunodeficiency virus (HIV) infection, Hepatitis B, or Hepatitis C
  • Are pregnant or breastfeeding

Contact Information
Charlotte Sklow, Study Coordinator
1695 Eastchester Rd. Bronx, NY 10461
Phone: (718) 862-8840 Ext. 436
Email: charlotte.sklow@einsteinmed.org

 

 

Postoperative Nausea and Vomiting

People with Pain Management are asked to participate in a research study being conducted by Montefiore Medical Center.

You may be eligible to participate in this study if you:

  • Are a male or female at least 18 years of age
  • Are planned to undergo elective surgery under general inhalation anesthesia
  • Have ≥3 of the following risks factors
    • Have a history of PONV and/or motion sickness
    • Are a nonsmoker for the year prior
    • Are female at birth
    • Are considered likely to require opioid analgesia postoperatively

You may NOT participate in this study if you:

  • Have received anti-cancer chemotherapy within 4 weeks
  • Are scheduled to undergo transplant surgery, cranial surgery, cardiac surgery, or any

Surgery

  • Have received aprepitant, fosaprepitant, or netupitant within 2 weeks

prior to the planned surgery date

  • Have received treatment for vestibular disease
  • Have clinically significant congestive heart failure, cardiac arrhythmia, or congenital long

QT syndrome

  • Have concurrent or expected use of apomorphine
  • Are pregnant or breastfeeding

Contact Information
Celina Joco, Study Coordinator
Phone: (718) 920-7178
Email: CJOCO@MONTEFIORE.ORG

 

 

 

 

 

 

 

Vulvar High-Grade Squamous Intraepithelial Lesion (HSIL)

People with Vulvar High-Grade Squamous Intraepithelial Lesion (HSIL) are asked to participate in a research study being conducted by Montefiore Medical Center.

You may be eligible to participate in this study if you:

  • Are US-based English- and Spanish-speaking individuals (aged 18+years) with vulvar HSIL
  • Were enrolled in Inovio’s HPV-201 clinical trial and who are within 6 months past their HPV-201 trial final visit (or early termination)

Contact Information
Natasha Rambishun , Study Coordinator
1695 Eastchester Road suite 505.
Bronx, NY 10461.
Phone: (718)-405-8396
Email: NRAMBISH@montefiore.org

 

Adult Patients with Advanced Solid Tumors

People with Advanced Solid Tumors are asked to participate in a research study being conducted by Montefiore Medical Center.

You may be eligible to participate in this study if you:

Have either:

NSCLC and documented PD-L1 expression on ≥50% of tumor cells

OR

HPV+ squamous cell carcinoma (SCC) with at least 1% PD-L1 expression

And:

  • Are at least 18 years of age
  • Had prior first line treatment with either anti-PD-1 monotherapy, anti-PD-1/chemotherapy or chemotherapy regimen
  • Can provide tumor tissue

You may NOT participate in this study if you:

  • Have had no previous local standard of care chemotherapy
  • Have had any treatment other than anti-PD-1 or platinum based chemotherapy
  • Have an active infection
  • Have active or known latent tuberculosis
  • Has active or known history of hepatitis
  • Diagnosis of acute coronary syndrome
  • Patients with congestive heart failure
  • Have an active autoimmune disease or a documented history of autoimmune disease (exceptions apply)
  • Are seropositive for human immunodeficiency viruses (HIV), hepatitis B or C
  • Are pregnant or breastfeeding

Contact Information
Charlotte Sklow, Study Coordinator
1695 Eastchester Rd. Bronx, NY 10461
Phone: (718) 862-8840 Ext. 436
Email: charlotte.sklow@einsteinmed.org

 

 

 

Urothelial Cancer – Immunomedics – PRA Health

People with Urothelial Cancer are asked to participate in a research study being conducted by Montefiore Medical Center.

You may be eligible to participate in this study if you:

  • Are a male or female at least 18 years of age
  • Have histologically documented metastatic or locally advanced unresectable UC
  • Have adequate hematologic counts
  • Have adequate hepatic function

You may NOT participate in this study if you:

  • Have had a prior anti-cancer mAb/ ADC within 4 weeks
  • Have received prior chemotherapy for UC
  • Have not recovered from AEs due to previously administered chemotherapeutic agent.
  • Have an active second malignancy
  • Have active cardiac disease
  • Have active chronic inflammatory bowel disease
  • Have an active serious infection
  • Have known immunodeficiency virus (HIV) infection, Hepatitis B or C
  • Are pregnant or breastfeeding

Contact Information
Mary Portes, Study Coordinator
1695 Eastchester Road Bronx, NY 10461
Phone: (718) 405-8209
Email: mportes@montefiore.org

 

 

 

 

 

 

 

Refractory Gastrointestinal Tract Tumors- EPON-PRIME

People with Advanced, Refractory Gastrointestinal Tract Tumors are asked to participate in a research study being conducted by Montefiore Medical Center.

You may be eligible to participate in this study if you:

  • Are a male or female at least 18 years of age
  • Have advanced, metastatic or unresectable GI tract tumors that are refractory or intolerant to existing available therapies
  • Have adequate bone marrow, liver, and renal function
  • Have not received treatment with IV 5-FU or oral 5-FU analogs in the 4 weeks
  • Hepatitis C or B infection and received antiviral treatment, has a negative viral load at Screening
  • The HIV infection, it is controlled with undetectable viral load with antiretroviral treatment

You may NOT participate in this study if you:

  • Have current brain metastasis
  • Have other clinically significant cardiac disease
  • Have had major surgery, open biopsy, or significant traumatic injury within 4 weeks
  • Have other primary cancer requiring treatment within the last 3 years
  • Have congenital long QT syndrome or a family history of long QT syndrome
  • Have a history or presence of clinically significant abnormal 12-lead ECG
  • Are pregnant or lactating

Contact Information
Mohammad Ghalib, Study Coordinator
1695 Eastchester Road, 2nd Floor
Bronx, New York 10461
Phone: (718) 405-8515
Email: mhghalib@montefiore.org

 

Diabetic Foot Ulcers (AMBULATE DFU II)

People with Diabetic Foot Ulcers are asked to participate in a research study being conducted by North Shore University Hospital.

You may be eligible to participate in this study if you:

  • Are a male or female at least 18 years of age
  • Have confirmed diagnosis of Type I or Type II diabetes
  • Have history, signs or symptoms leading to a clinical suspicion of osteomyelitis
  • Are under the care of a physician for the management of Diabetes Mellitus

You may NOT participate in this study if you:

  • Have malignancy or a history of cancer
  • Have a contralateral major amputation of the lower extremity
  • Have index ulcer is primarily located on the dorsal surface of the foot
  • Are pregnant or breastfeeding

Contact Information
Sally Kaplan, Study Coordinator
Phone: (516) 562-4578
Email: Skaplan2@northwell.edU

 

Patients with AML

People with Acute Myeloid Leukemia are asked to participate in a research study being conducted by Montefiore Medical Center.

You may be eligible to participate in this study if you:

  • Are a male or female at least 18 years of age
  • Are eligible to receive donor-derived MT-401
  • Have adequate blood, liver, and renal function

You may NOT participate in this study if you:

  • Have clinically significant or severely symptomatic intercurrent infection
  • Have evidence of acute or chronic GVHD ≥Grade 2
  • Are taking systemic corticosteroids
  • Are pregnant or lactating

Contact Information
Joel Victor, Study Coordinator
111 E. 210th Street Bronx, NY 10467
Phone: (718) 379-6863
Email: mmirande@montefiore.org

 

CIVO-Presage

People with solid tumors are asked to participate in a research study being conducted by Montefiore Medical Center.

You may be eligible to participate in this study if you:

  • Are a male or female at least 18 years of age
  • Have at least one lesion (tumor or effaced lymph node) that meets the size requirements of the study that your doctor thinks is suitable for an injection

You may NOT participate in this study if you:

  • Have received neoadjuvant therapy associated with the surgical intervention
  • Have any uncontrolled intercurrent illness, condition, or serious medical or psychiatric illness
  • Have received a live vaccine within 4 weeks
  • Have known HIV/AIDS infection with uncontrolled viral load
  • Are pregnant or breastfeeding

Contact Information
Stelby Augustine, Study Coordinator
3400 Bainbridge Avenue, 3rd Floor MAP Building
Bronx, New York 10467
Phone: 718 920 7054
Email: STAUGUST@montefiore.org

EGFRmutated Non-Small Cell Lung Cancer (NSCLC)

People with Non Small Cell Lung Cancer are asked to participate in a research study being conducted by Montefiore Medical Center.

You may be eligible to participate in this study if you:

  • Are a male or female at least 18 years of age
  • Have histologically or cytologically documented locally advanced or metastatic NSCLC
  • Have documentation of radiological disease progression while on/after receiving most recent treatment regimen
  • Have adequate bone marrow reserve and organ function,

You may NOT participate in this study if you:

  • Have unresolved toxicities from previous anticancer therapy
  • Have any evidence of severe or uncontrolled diseases
  • Have any previous or current histologic or cytologic evidence of small cell OR combined small cell/non-small cell disease
  • Have known immunodeficiency virus (HIV) infection, hepatitis B or C
  • Are pregnant or breastfeeding

Contact Information
Cristal Garcia, Study Coordinator
1695 Eastchester Rd. Bronx, NY 10461
Phone: (718) 405-8477
Email: crigarci@montefiore.org

 

 

Metastatic Non Small Cell Lung Cancer

People with Metastatic Non Small Cell Lung Cancer are asked to participate in a research study being conducted by Montefiore Medical Center.

You may be eligible to participate in this study if you:

  • Are a male or female at least 18 years of age
  • Have a histologically or cytologically confirmed diagnosis of metastatic NSCLC
  • Have adequate organ function

You may NOT participate in this study if you:

  • Have known active or untreated CNS metastases and/or carcinomatous meningitis.
  • Have a known history of an additional malignancy
  • Have a known history of interstitial lung disease
  • Has received prior systemic anticancer therapy
  • Have had major surgery
  • Have had an allogenic tissue/solid organ transplant.
  • Are currently participating in or has participated in a study of an investigational agent or have used an investigational device within 4 weeks before the first dose
  • Have known immunodeficiency virus (HIV) infection, hepatitis B or C
  • Are pregnant or breastfeeding

Contact Information
Cristal Garcia, Study Coordinator
1695 Eastchester Road – Bronx, NY 10461
Phone: (718) 405-8477
Fax: (718) 405-8230
Email: crigarci@montefiore.org

Unresectable Hepatocellular Carcinoma (STELLAR)

People with Hepatocellular Unresectable Carcinoma are asked to participate in a research study being conducted by Montefiore Medical Center.

You may be eligible to participate in this study if you:

  • Provide signed informed consent to participate in the study
  • Have advanced or unresectable HCC for whom a decision has been made by the treating physician (at their discretion) to initiate lenvatinib or sorafenib treatment

Contact Information
Charlotte Sklow, Study Coordinator
Department of Medical Oncology
Montefiore Medical Center
1695 Eastchester Rd, Bronx, NY 10461
Office: (718) 405-8535
Fax: (718) 405-8230

charlotte.sklow@einsteinmed.org

Metastatic Head and Neck Squamous Cell Carcinoma

People with Head and Neck Squamous Cell Carcinoma are asked to participate in a research study being conducted by Montefiore Medical Center.

You may be eligible to participate in this study if you:

  • Are a male or female at least 18 years of age
  • Have histologically and/or cytologically-confirmed HNSCC
  • Have received no more than two prior lines of systemic treatment for HNSCC
  • Have adequate bone marrow function and organ function

You may NOT participate in this study if you:

  • Have a known hypersensitivity and/or contraindication to paclitaxel
  • Are concurrently using or has used another approved or investigational cancer agent within last 4 weeks of screening
  • Are currently receiving increasing or chronic treatment
  • Have known history of immunodeficiency virus (HIV) infection
  • Have impairment of gastrointestinal (GI) function or GI disease
  • Are pregnant or breastfeeding

Contact Information
Cristal Garcia, Study Coordinator
1695 Eastchester Rd. Bronx, NY 10461
Phone: (718) 405-8477
Email: crigarci@montefiore.org

 

 

 

Metastatic Colorectal Cancer

People with Colorectal Cancer are asked to participate in a research study being conducted by Northwell Health.

You may be eligible to participate in this study if you:

  • Are a male or female at least 18 years of age
  • Have at least one systemic treatment for mCRC
  • Have adequate hematological, renal, and hepatic function

You may NOT participate in this study if you:

  • Have received major surgery within 28 days
  • Have had prior chemotherapy, biological therapy, radiation therapy, hormonal therapy for anti-cancer purposes
  • Have brain metastasis
  • Have impaired cardiac function
  • Have past or current history of neoplasm other than mCRC,
  • Have known immunodeficiency virus (HIV) infection, hepatitis B, or C
  • Are pregnant or breastfeeding

Contact Information
Adrianna Kapusta, Study Coordinator
450 Lakeville Rd. Lake Success, NY 11042
Phone: (516) 734-8896
Email: aKapusta@northwell.edu

Non-Hodgkin Lyphoma

People with Hodgkin Lymphoma are asked to participate in a research study being conducted by Icahn School of Medicine at Mount Sinai.

You may be eligible to participate in this study if you:

  • Are a male or female at least 18 years of age
  • Are CD20-positive NHL
  • Have acceptable organ function
  • Agree not to donate blood for 60 days after receiving the last dose of trial treatment

You may NOT participate in this study if you:

  • Have suspected active or latent tuberculosis
  • Have known immunodeficiency virus (HIV) infection, hepatitis B or C
  • Have evidence of significant, uncontrolled concomitant diseases
  • Have known active bacterial, viral, fungal, mycobacterial, parasitic, or other infection
  • Are pregnant or breastfeeding

Contact Information
Alexis Mark, Study Coordinator
One Gustave L. Levy Place, New York NY 10029
Phone: (212) 824-7325 Ext. 57325
Email: Alexis.Mark@mssm.edu

 

Muscle-invasive Bladder Cancer

People with Muscle-invasive Bladder Cancer are asked to participate in a research study being conducted by White Plains Hospital.

You may be eligible to participate in this study if you:

  • Are a male or female at least 18 years of age
  • Have histologically confirmed diagnosis of urothelial carcinoma
  • Have clinically non-metastatic bladder cancer
  • Have a TUR of a bladder tumor

You may NOT participate in this study if you:

  • Have a known additional non-urothelial malignancy that is progressing or has required active anticancer treatment ≤3 years prior to study
  • Have received any prior systemic treatment, chemoradiation, and/or radiation therapy treatment for MIBC
  • Are cisplatin-ineligible
  • Have known history of immunodeficiency virus (HIV) infection, hepatitis B, or active hepatitis C
  • Have a history of uncontrolled diabetes or pneumonitis
  • Are pregnant or breastfeeding

Contact Information
Hyemin Kim, Study Coordinator
2 Longview Avenue White Plains, NY 10601
Phone: 914-849-7591
Fax: 914-849-7598
Email: hkim3@wphospital.org

Severe Asthma

People with asthma are asked to participate in a research study being conducted by Long Island Jewish Medical Ctr.

You may be eligible to participate in this study if you:

  • Are an adult or adolescent ≥12 years of age
  • Have a documented physician diagnosis of asthma
  • Have current treatment with at least one additional controller medication

You may NOT participate in this study if you:

  • Have a presence of a known pre-existing, clinically important lung condition other than asthma
  • Have a current malignancy or previous history of cancer in remission for less than 12 months
  • Have an have active COVID-19 infection
  • Have cirrhosis or current unstable liver or biliary disease
  • Have a known, pre-existing parasitic infestation
  • Have known immunodeficiency virus (HIV) infection
  • Are pregnant or breastfeeding

Contact Information
Ramona Ramdeo, Study Coordinator
Phone: (516) 465-5461
Email: rramdeo@northwell.edu

Myelomonocytic Leukemia

People with Leukemia are asked to participate in a research study being conducted by Montefiore Medical Center.

You may be eligible to participate in this study if you:

  • Are a male or female at least 18 years of age
  • Have recovered from the reversible effects of prior anticancer therapy
  • Have have a histologically or cytologically confirmed metastatic or locally advanced solid tumor
  • Have morphologically confirmed diagnosis of MDS or nonproliferative CMML

You may NOT participate in this study if you:

  • Have end-stage renal disease requiring hemodialysis
  • Have had major surgery within 14 days
  • Have Gilbert syndrome or cardiopulmonary disease
  • Have known hypersensitivity to pevonedistat
  • Have Active uncontrolled infection or severe infectious disease
  • Have known immunodeficiency virus (HIV) infection, hepatitis B or C
  • Are pregnant or breastfeeding

Contact Information
Mohammad Ghalib, Study Coordinator
1695 Eastchester Road, 2nd floor
Bronx, NY 10461
Phone: (718) 405-8515
Email: mhghalib@montefiore.org

Atypical BRAF Alterations – CMed

People with Advanced Malignancies Harboring MEK or Atypical BRAF Alterations are asked to participate in a research study being conducted by Montefiore Medical Center.

You may be eligible to participate in this study if you:

  • Are a male or female at least 18 years of age
  • Have a locally advanced or metastatic malignancy
  • Have adequate renal, hepatic, cardiac, and bone marrow function
  • Have a tumor harboring a MEK or atypical BRAF alteration

You may NOT participate in this study if you:

  • Have Gastrointestinal (GI) condition that could impair absorption of study medication
  • Have known uncontrolled brain metastases
  • Have had major surgery within 4 weeks prior to first dose.
  • Have received any cancer-directed therapy
  • Have any evidence of serious active infections
  • Are pregnant or breastfeeding

Contact Information
Mohammad Ghalib, Study Coordinator
1695 Eastchester Road, 2nd floor
Bronx, NY 10461
Phone: (718) 405-8515
Email: mhghalib@montefiore.org

 

In-Stent Restenosis (ISR)

People with in-stent restenosis (isr) are asked to participate in a research study being conducted by Montefiore Medical Center.

You may be eligible to participate in this study if you:

  • Are a male or female at least 18 years of age
  • Are eligible for percutaneous coronary intervention (PCI)
  • Are willing to comply with all protocol-required follow-up evaluation

You may NOT participate in this study if you:

  • Have other serious medical illness (e.g. cancer, congestive, heart failure)
  • Have participating in another investigational drug or device clinical study
  • Have known allergies against paclitaxel or other components of the used medical devices
  • Have had PCI or other coronary interventions
  • Have renal insufficiency
  • Have suspected or proven COVID-19 at present or within the past 2 weeks.
  • Are pregnant or breastfeeding

Contact Information
Angeline Camilo, Study Coordinator
Phone: (718) 920-4595
Email: acamilo@montefiore.org

 

Mitral Regurgitation

People with Functional Mitral Regurgitation are asked to participate in a research study being conducted by Montefiore Medical Center.

You may be eligible to participate in this study if you:

  • Are a male or female at least 18 years of age
  • Have moderate to severe (3+) or severe (4+) functional mitral regurgitation
  • Are a candidate for annuloplasty
  • Are symptomatic despite guideline directed medical therapy

You may NOT participate in this study if you:

  • Have any planned cardiac surgery within the next 12 months
  • Are on a waiting list for a transplant or have had a prior heart transplant
  • Have had carotid surgery within 30 days
  • Have renal insufficiency
  • Are pregnant or breastfeeding

Contact Information
Angeline Camilo, Study Coordinator
Phone: (718) 920-4595
Email: acamilo@montefiore.org

 

Non-Small Cell Lung Cancer

People with Non-Small Cell Lung Cancer are asked to participate in a research study being conducted by Montefiore Medical Center.

You may be eligible to participate in this study if you:

  • Are a male or female at least 18 years of age
  • Have no prior systemic anti-cancer treatment
  • Have histologically confirmed metastatic NSCLC

You may NOT participate in this study if you:

  • Have a condition requiring systemic treatment
  • Have leptomeningeal metastases
  • Have an active, known, or suspected autoimmune disease
  • Have serious or uncontrolled medical disorder
  • Have severe acute respiratory coronavirus 2 (SARS-CoV-2) infection
  • Are pregnant or breastfeeding

Contact Information
Cristal Garcia, Study Coordinator
1695 Eastchester Rd. Bronx, NY 10461
Phone: (718) 405-8477
Email: crigarci@montefiore.org

Follicular Lymphoma

People with Follicular Lymphoma are asked to participate in a research study being conducted by Northwell Health.

You may be eligible to participate in this study if you:

  • Are a male or female at least 18 years of age
  • Have histologically confirmed Follicular Lymphoma
  • Have been previously treated with at least 1 prior systemic chemotherapy, immunotherapy, or chemoimmunotherapy
  • Have adequate liver, renal, and bone marrow function

You may NOT participate in this study if you:

  • Have received major surgery within 4 weeks before the first dose of study drug
  • Have thrombocytopenia, neutropenia, or anemia
  • Have significant cardiovascular impairment or an active infection requiring systemic therapy
  • Have prior exposure to lenalidomide.
  • Have known immunodeficiency virus (HIV) infection
  • Are pregnant or breastfeeding

Contact Information
Arpana Manuel, Study Coordinator
450 Lakeville Road, Lake Success, NY 11042
Phone: (516) 734-7217
Fax: (516) 734-8909
Email: amanuel2@northwell.edu

Prostate Cancer

People with prostate cancer are asked to participate in a research study being conducted by Montefiore Medical Center.

You may be eligible to participate in this study if you:

  • Are a male at least 18 years of age or meeting country definition of adult
  • Have histologically or cytologically confirmed adenocarcinoma of the prostate
  • Have measurable metastatic disease
  • Have progressive disease at study entry
  • Have adequate organ and marrow function

You may NOT participate in this study if you:

  • Have received radiation therapy within 4 weeks of study start
  • Have known brain metastases or cranial epidural disease
  • Have prior nonhormonal therapy initiated for the treatment of mCRPC.
  • Have uncontrolled, significant intercurrent or recent illness
  • Have had major had surgery within 4 weeks of study start

Contact Information
Mary Portes, Study Coordinator
1695 Eastchester Road Bronx, NY 10461
Phone: (718) 405-8209
Email: mportes@montefiore.org

 

PROCADE prostate cancer

People with prostate cancer are asked to participate in a research study being conducted by Montefiore Medical Center.

You may be eligible to participate in this study if you:
• Are a male at least 18 years of age or older
• Have histologically or cytologically confirmed adenocarcinoma of the prostate

You may not participate in this study if you:
• Have a history of another malignancy within the previous two years other than curatively treated non-melanomatous skin cancer
• Have used any other investigational agent within the past four weeks
• Have had a gastrointestinal disorder affecting absorption such as gastrectomy or active peptic ulcer disease within the last three months

Contact Information
Mary Portes, Study Coordinator
1695 Eastchester Road
Bronx, New York 10461
Phone: (718) 405-8209
Email: mportes@montefiore.org

COSTAR Lung 213410 Prior Anti-Pd-(L)1 Therapy with Platinum Chemotherapy

People with Non-Small Cell Lung Cancer are asked to participate in a GlaxoSmithKline research study being conducted by Montefiore Medical Center.

You may be eligible to participate in this study if you:

• Are a male or female ≥18 years of age
• Have histologically or cytologically proven advanced or metastatic NSCLC
• Have received no more than 2 prior lines of therapy
• Have adequate organ function

You may NOT participate in this study if you:

• Have received investigational treatment in another clinical study within the past 4 weeks
• Have received radiation to the lung in the last 6 months
• Have known immunodeficiency virus (HIV) infection, hepatitis B or C
• Have current interstitial lung disease, current pneumonitis,
• Have received a live vaccine in the last 30 days
• Are pregnant or breastfeeding

Contact Information
Cristal Garcia, Study Coordinator
1695 Eastchester Rd. Bronx, NY 10461
Phone: (718) 405-8477
Email: CRIGARCI@MONTEFIORE.ORG

COSTAR Lung 213410 Prior Anti-Pd-(L)1 Therapy with Platinum Chemotherapy

People with Non-Small Cell Lung Cancer are asked to participate in a GlaxoSmithKline research study being conducted by White Plains Hospital.

You may be eligible to participate in this study if you:
• Are a male or female ≥18 years of age
• Have histologically or cytologically proven advanced or metastatic NSCLC
• Have received no more than 2 prior lines of therapy
• Have adequate organ function

You may NOT participate in this study if you:
• Have received investigational treatment in another clinical study within the past 4 weeks
• Have received radiation to the lung in the last 6 months
• Have known immunodeficiency virus (HIV) infection, hepatitis B or C
• Have current interstitial lung disease, current pneumonitis,
• Have received a live vaccine in the last 30 days
• Are pregnant or breastfeeding

Contact Information
Hyemin Kim, Study Coordinator
2 Longview Avenue
White Plains, New York 10601
Phone: (914) 849-7591
Email: hkim3@wphospital.org

Breast Cancer DESTINY-05

People with breast cancer are asked to participate in a research study being conducted by Montefiore Medical Center.

You may be eligible to participate in this study if you:
• Are a male or female at least 18 years of age
• Have HER2-positive breast cancer
• Have adequate organ function
• Have an interval of no more than 12 weeks between the date of last surgery
• Have completion of neoadjuvant systemic chemotherapy and HER2-directed treatment

You may NOT participate in this study if you:
• Have an uncontrolled infection
• Have unresolved toxicities from previous anticancer therapy
• Have stage IV (metastatic) breast cancer
• Have history of any prior breast cancer
• Have known immunodeficiency virus (HIV) infection, hepatitis B or C
• Are pregnant or breastfeeding

Contact Information
Ambar Baez, Study Coordinator
111 E 210th Street
Bronx, NY 10467
Phone: (718) 920-2006
Email: AMBAEZ@MONTEFIORE.ORG

Advanced Solid Tumors with KRAS G12C Mutation

People with Advanced Solid Tumors with KRAS G12C Mutation are asked to participate in a research study being conducted by Monter Cancer Center.

You may be eligible to participate in this study if you:
• Are a male or female at least 18 years of age
• Have histologically confirmed diagnosis of a solid tumor malignancy
• Have presence of tumor lesions

You may NOT participate in this study if you:
• Have active brain metastases
• Have undergone major surgery within 4 weeks of first dose date
• Have carcinomatous meningitis
• Have a history of stroke or transient ischemic attack
• Have known immunodeficiency virus (HIV) infection, hepatitis B, or C
• Are pregnant or breastfeeding

Contact Information
Alexa Amoroso, Study Coordinator
450 Lakeville Road, Lake Success, NY 11042
Phone: (516) 734-8977
Email: AAMOROSO1@NORTHWELL.EDU

PROSTATE CANCER De Novo Metastatic Hormone-Sensitive Prostate Cancer (mHSPC)

People with prostate cancer are asked to participate in a research study being conducted by Montefiore Medical Center.

You may be eligible to participate in this study if you:

• Are a male at least 18 years of age
• Are able and willing to swallow and retain oral medication
• Consent to provide a FFPE tissue block
• Have Asymptomatic or mildly symptomatic form of prostate cancer

You may NOT participate in this study if you:
• Have received major surgery within 4 weeks of study start
• Have brain metastases, or spinal cord compression
• Have past medical history of interstitial lung disease, drug-induced interstitial lung disease, radiation pneumonitis
• Have clinically significant heart disease
• Have inadequate bone marrow reserve or organ function

Contact Information
Mary Portes, Study Coordinator
1695 Eastchester Rd, 5th floor Room # 503,
Bronx, NY-10461
Phone: (718) 405-8209
Email: MPORTES@MONTEFIORE.ORG

Non-Small Cell Lung Cancer NSCLC Prior Anti-Pd-(L)1 Therapy with Chemotherapy

People with Non-Small Cell Lung Cancer are asked to participate in a research study being conducted by White Plains Hospital.

You may be eligible to participate in this study if you:

  • Are a male or female ≥18 years of age
  • Have histologically or cytologically proven advanced or metastatic NSCLC
  • Have received no more than 2 prior lines of therapy
  • Have adequate organ function

You may NOT participate in this study if you:

  • Have received investigational treatment in another clinical study within the past 4 weeks
  • Have had radiological or clinical disease progression
  • Have received radiation to the lung
  • Have known immunodeficiency virus (HIV) infection, hepatitis B or C
  • Have current interstitial lung disease, current pneumonitis, or a history of pneumonitis
  • Have received a live vaccine or prior anticancer therapy
  • Are pregnant or breastfeeding

 
Contact Information
Hyemin Kim, Study Coordinator
2 Longview Avenue
White Plains, New York 10601
Phone: (914) 849-7591
Email: hkim3@wphospital.org

 

Long Lasting Lenacapavir HIV

People with HIV are asked to participate in a research study being conducted by Montefiore Medical Center.

You may be eligible to participate in this study if you:

• Are Cisgender Men, Transgender Women, Transgender Men, and Gender Non-binary people at least 16 years of age
• Have HIV-1 status unknown at screening and no prior HIV-1 testing within the last 3 months
• Are sexually active with ≥ 1 partner assigned male at birth (condomless anal sex)

You may NOT participate in this study if you:

• Have prior vaccine trial participation
• Are participating in any other clinical trial
• Have acute viral hepatitis A, B or C or evidence of chronic hepatitis B or C infection
• Have a suspected or known active, serious infection(s)
• Have a history of osteoporosis or bone fragility fractures

Contact Information
Tina Alford, Study Coordinator
Phone: 718-882-0023
Email: TALFORD@ADOLESCENTAIDS.ORG

Abbvie – Myelofibrosis – M16 -191

People with Myelofibrosis are asked to participate in a research study being conducted by Monter Cancer Center.

You may be eligible to participate in this study if you:

  • Are a male or female at least 18 years of age
  • Have adequate bone marrow reserve
  • Have adequate renal & hepatic function and enzymes

You may NOT participate in this study if you:

  • Subjects must meet all of the criteria in the protocol in order to be included in the study. Anything other than a positive response to the questions in the protocol will result in exclusion from study participation.

Contact Information
Carolyn Pellizzari,Study Coordinator
450 Lakeville Road Lake Success, New York 11042
Email: cpellizzar@northwell.edu
Telephone: (516) 734-8921

 

Primary Biliary Cholangitis (PBC) Assure

People with Primary Biliary Cholangitis (PBC) are asked to participate in a research study being conducted by North Shore University Hospital.

You may be eligible to participate in this study if you:

• Have given informed consent (signed and dated)
• Have participated in a PBC study with seladelpar
• Are a female of reproductive potential, you must use at least one barrier contraceptive and a second effective birth control method during the study

You may NOT participate in this study if you:

• Have use of an experimental or unapproved treatment for PBC within 3 months
• Have a known history of chronic viral hepatitis
• Have auto-immune hepatitis
• Have a history of malignancy diagnosed or treated, actively or within 2 years, or active
evaluation for malignancy
• Have had treatment with any other investigational therapy or medical device within 30 days
• Are pregnant or breastfeeding

Contact Information
Radica Palmer, Study Coordinator
400 Community Drive Manhasset, NY 11030
Phone: (516) 562-2082
Email: RPalmer@northwell.edu

Non-Muscle Invasive Bladder Cancer BOND-003

People with Non-Muscle Invasive Bladder Cancer are asked to participate in a research study being conducted by Montefiore Medical Center.

You may be eligible to participate in this study if you:

  • Are a male or female at least 18 years of age
  • Have pathologically confirmed CIS
  • Have received prior adequate BCG therapy
  • Are ineligible to receive radical cystectomy or refusal of radical cystectomy
  • Demonstrate adequate organ function

You may NOT participate in this study if you:

  • Have received systemic anti-cancer therapy or systemic treatment, radiation therapy, or surgery for bladder cancer
  • Have significant immunodeficiency due to underlying illness or hepatitis B or C
  • Have received systemic immunosuppressive medication
  • Have had prior organ or allogenic stem cell transplant
  • Have an active infection
  • Are pregnant or breastfeeding

Contact Information

JoAnn Horn, CCRC, Study Coordinator
1250  Waters Place, Bronx, NY  10461
Phone (347)842-1715
Email:  Johor@montefiore.org

 

Tabelecleucel Epstein-Barr Virus

People with Epstein-Barr virus are asked to participate in a research study being conducted by Montefiore Medical Center.

You may be eligible to participate in this study if you:

  • Are a male or female of any age
  • Have adequate organ function
  • Have a diagnosis of EBV+ disorder

You may NOT participate in this study if you:

  • Have serious known active infections
  • Have suspected or confirmed grade ≥ 2 acute GvHD
  • Have a need for vasopressor or ventilatory support
  • Are actively receiving chemotherapy
  • Are pregnant or breastfeeding

Contact Information
Elaine Chung, Data Analyst & Study Coordinator
3411 Wayne Avenue, 9th Floor, Bronx, NY 10467
Phone: 718-741-2840 or Cell: 917-717-4173
Email: elchung@montefiore.org

Metastatic Castration Resistant Prostate Cancer

People with Prostate Cancer are asked to participate in a research study being conducted by Montefiore Medical Center.

You may be eligible to participate in this study if you:

  • Are a male or female at least 18 years of age
  • Have histologically or cytologically confirmed adenocarcinoma of the prostate
  • Have metastatic prostate cancer disease
  • Are surgically or medically castrated
  • Have had no prior treatment with cytotoxic chemotherapy
  • Demonstrate adequate organ function

You may NOT participate in this study if you:

  • Have known symptomatic brain metastases.
  • Have clinically significant cardiovascular disease
  • Have untreated or impending spinal cord compression
  • Have a severe concurrent disease, infection, or comorbidity
  • Have a history of seizure
  • Have had major surgery within 4 weeks
  • Have known immunodeficiency virus (HIV) infection, hepatitis B or C

Contact Information
Mary Portes, Study Coordinator
1695 Eastchester Road, Bronx, New York 10461
Phone: (718) 405-8209
Email: mportes@montefiore.org

Myelofibrosis Who Have Suboptimal Response to Ruxolitinib

People with Myelofibrosis are asked to participate in a research study being conducted by Montefiore Medical Center.

You may be eligible to participate in this study if you:

• Are a male or female at least 18 years of age
• Have a diagnosis of PMF, PPV-MF, or PET-MF
• Have DIPSS risk category of intermediate-1, intermediate-2, or high
• Have been treated with ruxolitinib for ≥ 3 months with a stable dose for at least the last 8 weeks

You may NOT participate in this study if you:

• Have received prior therapy with any drug that inhibits PI3K
• Have recent history of inadequate bone marrow reserve
• Have inadequate liver or renal function
• Have uncontrolled, severe, or unstable cardiac disease
• Have known immunodeficiency virus (HIV) infection
• Have an active bacterial, fungal, parasitic, or viral infection
• Are pregnant or breastfeeding

Contact Information
Hieu Liem Nguyen, Study Coordinator
1300 Morris Park Ave, Ullmann Building Rm 921
Bronx, NY 10461Phone: (718) 325-9392
Email: hinguyen@montefiore.org

 

Small cell lung cancer (SCLC) Receiving Zepzelca

People with SMALL CELL LUNG CANCER are asked to participate in a research study being conducted by Montefiore Medical Center.

You may be eligible to participate in this study if you:

  • Are receiving Zepzelca treatment in line with the Zepzelca US prescribing information
  • Made decision to initiate treatment with Zepzelca was made as per investigator’s routine treatment practice prior to enrollment
  • Sign the informed consent before any study-related activities are undertaken

You may NOT participate in this study if you:

  • Have discontinued a prior Zepzelca treatment due to adverse events
  • Have received more than 2 cycles of Zepzelca treatment in current treatment schedule.
  • Have received treatment with any investigational agent

Contact Information
Charlotte Sklow, Study Coordinator
1695 Eastchester Rd. Bronx, NY 10461
Phone: (718) 862-8840 Ext. 436
Email: charlotte.sklow@einsteinmed.org

COVID-19 Treatment Outpatient

Summary: People with COVID-19 are asked to participate in a research study being conducted by Montefiore Medical Center.

You may be eligible to participate in this study if you:

• Are a male or female at least 18 years of age
• Have symptomatic, diagnostically confirmed COVID-19
• Have either become symptomatic or found positive by RT-PCR
• Have at least two symptoms of at least moderate severity
• Have acceptable hematologic status

You may NOT participate in this study if you:

  • Are in need of acute hospitalization
  • Have receiving, has received within the past 7 days or is expected
    to receive during the course of the study remdesivir, chloroquine,
    hydroxychloroquine, azithromycin or other specific antiviral therapy
  • Are currently taking or is expected to start taking warfarin, apixabain
    (Eliquis), argatroban, or rivaroxaban (Xarelto)
  • Are pregnant or breastfeeding

Contact Information
Magdalena Mamczur-Madry, Study Coordinator
Phone: (718) 920-3576
Email: MMAMCZUR@MONTEFIORE.ORG

 

Avelumab in UroThelIal CarcInoma-PATRIOIT-II

People with Urothelial Carcinoma are asked to participate in a research study being conducted by Montefiore Medical Center.

You may be eligible to participate in this study if you:

  • Are a male or female at least 18 years of age
  • Have histologically confirmed LA/mUC
  • Have LA/mUC whose disease did not progress on platinum-containing chemo

You may NOT participate in this study if you:

  • Have incomplete patient history data
  • Have interventional clinical trial participation at any point during the study period
  • Are pregnant

Contact Information
Mary Portes, Study Coordinator
1695 Eastchester Rd, 5th floor Room # 503,
Bronx, NY-10461
Phone: (718) 405-8209
Email: mportes@montefiore.org

 

ENHANCE

People with Myelodysplastic Syndrome are asked to participate in a research study being conducted by Montefiore Medical Center.

You may be eligible to participate in this study if you:

• Are a male or female at least 18 years of age
• Are willing to undergo blood transfusions
• Pretreatment blood cross-match completed
• Are previously untreated with MDS

You may NOT participate in this study if you:

• Have had any prior antileukemic therapy
• Have known inherited or acquired bleeding disorders
• Have significant medical diseases or conditions
• Have known immunodeficiency virus (HIV) infection, hepatitis B or C
• Are pregnant or breastfeeding

Contact Information
Joel Victor, Study Coordinator
111 E. 210th Street
Bronx, NY 10467
Phone: (718) 920-6680
Email: jovictor@montefiore.org

Advanced or Metastatic Non-small Cell Lung Cancer

People with Metastatic Non Small Cell Lung Cancer are asked to participate in a research study being conducted by Montefiore Medical Center.

You may be eligible to participate in this study if you:

  • Are a male or female at least 18 years of age
  • Can provide archival tumor tissue
  • Have left ventricular ejection fraction
  • Have adequate blood clotting function
  • Have had prior therapy requirements for advanced or metastatic NSCLC
  • Have adequate hepatic & bone marrow function

You may NOT participate in this study if you:

  • Have mixed small-cell lung cancer (SCLC) and NSCLC histology.
  • Have leptomeningeal carcinomatosis or metastasis
  • Have had prior treatment with platinum-based chemotherapy and prior immunotherapy
  • Have an uncontrolled infection
  • Have uncontrolled or significant cardiovascular disease
  • Have clinically significant corneal disease
  • Have known immunodeficiency virus (HIV) infection, hepatitis B or C
  • Are pregnant or breastfeeding

 
Contact Information

Cristal Garcia, Study Coordinator

1695 Eastchester Road
Bronx, NY 10461
Phone: (718) 405-8477
Email: crigarci@montefiore.org

Gene-Mutated Metastatic Castration-Sensitive Prostate Cancer (mCSPC)

People with prostate cancer are asked to participate in a research study being conducted by Montefiore Medical Center.

You may be eligible to participate in this study if you:
• Are a male or female at least 18 years of age
• Have a diagnosis of prostate adenocarcinoma
• Are willing to provide an archival tumor tissue sample or a fresh tumor tissue sample
• Are able to swallow the study medication tablets whole
• Have allowed prior treatments for localized prostate cancer

You may NOT participate in this study if you:
• Have a history of adrenal dysfunction
• Have Received an investigational intervention (including investigational vaccines) or used an invasive investigational medical device within 30 days before the planned first dose
• Have active malignancies
• Have known immunodeficiency virus (HIV) infection, hepatitis B or C
• Have had major surgery ≤28 days prior

Contact Information
Mary Portes, Study Coordinator
1695 Eastchester Road Bronx, NY 10461
Phone: (718) 405-8209
Email: mportes@montefiore.org

HUMAN EPIDERMAL GROWTH FACTOR RECEPTOR 2 (HER2) POSITIVE AND NEGATIVE SOLID

People with solid tumors are asked to participate in a research study being conducted by Monter Cancer Center.

You may be eligible to participate in this study if you:
• Are a male or female at least 18 years of age
• Have adequate bone marrow, liver, & renal function
• Are able provide a fresh biopsy sample
• Have documentation of histologically or cytologically confirmed diagnosis of HER2 IHC 1+ or IHC 2+/ISH- BC

You may NOT participate in this study if you:

• Have history of prior malignancy other than the diseases under study within the past 5 years
• Have had major surgery within 4 weeks prior to registration.
• Are pregnant or breastfeeding
• Have serious pulmonary illness
• Have an active inflammatory bowel disease, chronic diarrhea, short bowel syndrome, or any upper gastrointestinal surgery including gastric resection
• Have a history of, or ongoing, corneal disorder
• Have an active and clinically significant bacterial, fungal, or viral infection
• Have a history or active interstitial lung disease, pulmonary fibrosis, or a history of other clinically significant lung diseases.

Contact Information
Melissa Ramgadoo, Study Coordinator
450 Lakeville Road, Lake Success, New York 11042
Phone: (516) 734-8839
Email: mramgadoo@northwell.edu

Clinipace – Consellation – Phase 1 Solid Tumor

People with Advanced Solid Tumors are asked to participate in a research study being conducted by Montefiore Medical Center.

You may be eligible to participate in this study if you:
• Are a male or female at least 18 years of age
• Have adequate bone marrow function & renal function
• Have adequate hepatic function
• Are willing to provide blood and tumor samples

You may NOT participate in this study if you:
• Have had a previous solid organ or hematopoietic cell transplant.
• Have known symptomatic untreated brain metastases
• Have clinically significant cardiovascular disease
• Have had major surgery within 4 weeks before starting
• Have gastrointestinal disorder or an uncontrolled active infection
• Have known immunodeficiency virus (HIV) infection, hepatitis B or C
• Have a clinically active or symptomatic viral hepatitis or chronic liver disease
• Are pregnant or breastfeeding

Contact Information
Mohammad Ghalib, Study Coordinator
1695 Eastchester Road, 2nd floor
Bronx, NY 10461
Phone: (718) 405-8515
Email: mhghalib@montefiore.org

20-06-507

Allogeneic CRISPR-Cas9-Engineered T Cells (CTX130) in Adult Subjects

People with Relapsed or Refractory T or B Cell Malignancies are asked to participate in a research study being conducted by Montefiore Medical Center.

You may be eligible to participate in this study if you:
• Are a male or female at least 18 years of age and body weight ≥60 kg
• Have confirmed diagnosis of a T cell malignancy
• Have CD70-expressing tumors
• Have adequate organ function

You may NOT participate in this study if you:
• Have received prior treatment with anti-CD70 targeting agents
• Have clinical signs of HLH
• Have an uncontrolled, acute, life-threatening bacterial, viral, or fungal infection
• Have an unstable angina, arrhythmia, or myocardial infarction
• Have had prior solid organ transplantation
• Have known immunodeficiency virus (HIV) infection, hepatitis B, or hepatitis C virus
• Are pregnant or breastfeeding

Contact Information
Joel Victor, Study Coordinator
111 E. 210th Street Bronx, NY 10467
Phone: (718) 920-6680
Email: JOVICTOR@MONTEFIORE.ORG

ER+ HER2- metastatic breast cancer

People with metastatic breast cancer are asked to participate in a research study being conducted by Montefiore Medical Center.

You may be eligible to participate in this study if you:
• Are at least 18 years of age
• Have histologically or cytologically confirmed locally advanced or metastatic breast cancer
• Have any unresolved toxicities from prior therapy
• Have not have received prior oral endocrine therapy

You may NOT participate in this study if you:
• Have a prior or concurrent malignancy
• Have known impaired cardiac function or clinically significant cardiac disease
• Have known immunodeficiency virus (HIV) infection
• Have a history of cerebral vascular disease or liver disease
• Have an active infection
• Have a history of leptomeningeal disease or spinal cord compression
• Have an active brain metastases
• Are pregnant or breastfeeding

Contact Information
Ana Bernal Guarin, Study Coordinator
111 E. 210th Street Bronx, NY 10467
Phone: (718) 798-5687
Email: abernal@montefiore.org

Non-Small Cell Lung Cancer PRA – Mirati – Krystal Program – 849-007

People with Non-Small Cell Lung Cancer are asked to participate in a research study being conducted by Montefiore Medical Center.

You may be eligible to participate in this study if you:
• Are a male or female at least 18 years of age
• Have unresectable or metastatic disease
• Histologically confirmed diagnosis of NSCLC (squamous or nonsquamous) with KRAS G12C mutation and known PD-L1 Tumor Proportion Score (TPS) score

You may NOT participate in this study if you:
• Have received prior systemic treatment for locally advanced or metastatic NSCLC
• Major surgery within 4 weeks prior to first dose of study treatment
• Have active brain metastases.
• History of stroke or transient ischemic attack
• Have an active or prior documented autoimmune or inflammatory disease
• Have known immunodeficiency virus (HIV) infection, hepatitis B, or hepatitis C
• Are pregnant or breastfeeding

Contact Information
Cristal Garcia, Regulatory Coordinator
Department of Medical Oncology
Montefiore Medical Center
1695 Eastchester Road – Bronx, NY 10461
Phone: (718) 405-8477
Fax: (718) 405-8230
Email: crigarci@montefiore.org

Progressive Familial Intrahepatic Cholestasis

People with Familial Intrahepatic Cholestasis are asked to participate in a research study being conducted by Montefiore Medical Center.

You may be eligible to participate in this study if you:
• Are a male or female at least 18 years of age
• Have diagnosis of PFIC
• Have the ability to read and understand the questionnaires
• Have completed at least 21 valid* morning ItchRO(Obs) entries during 4 consecutive weeks of the screening period

You may NOT participate in this study if you:
• Current or recent history of atopic dermatitis or other non-cholestatic diseases associated with pruritus
• Any prior cancer diagnosis (except for in situ carcinoma) within 5 years
• Have known immunodeficiency virus (HIV) infection, hepatitis B, or hepatitis C
• Are pregnant or breastfeeding
• Presence of other liver disease or need for liver transplant
• Predicted complete absence of bile salt excretion pump (BSEP) function

Contact Information
Trang Nguyen, Study Coordinator
Phone: (718)-920-4321
Email: TRANNGUY@MONTEFIORE.ORG

Dyskinesia in Patients with Parkinson’s Disease – PPD 88366-01

People with Parkinson’s are asked to participate in a research study being conducted by Icahn School of Medicine at Mount Sinai.

You may be eligible to participate in this study if you:
• Are a male or female between age 30-85 years old
• Have Parkinson’s disease, per UK Parkinson’s Disease Society (UKPDS) Brain Bank Clinical Diagnostic Criteria
• Willing and able to comply with all study visits and procedures
• Are on a stable regimen of antiparkinson’s medications for at least 30 days prior to screening

You may NOT participate in this study if you:
• History of seizures within 2 years prior to screening
• History of stroke or transient ischemic attack (TIA) within 2 years prior to screening
• History of cancer within 5 years prior to screening
• Inability to swallow oral tablets
• Hoehn and Yahr Stage V
• Are pregnant or breastfeeding

Contact Information
Mindy Lopez, Study Coordinator
Phone: (212) 241-9038
Email: MINDY.LOPEZ1@MSSM.EDU

ENCIRCLE-Mitral Regurgitation

People with Mitral Regurgitation are asked to participate in a research study being conducted by Montefiore Medical Center.

You may be eligible to participate in this study if you:
• Are a male or female at least 18 years of age
• Are at high or prohibitive risk for mitral valve surgery
• Have stable heart failure medication regimen for at least 30 days prior to enrollment

You may NOT participate in this study if you:
• Have liver disease or Chronic obstructive pulmonary disease
• Have an active infection
• Have severe right ventricular dysfunction
• Have clinically significant untreated coronary artery disease
• Have leukopenia, anemia, or thrombocytopenia
• Are pregnant or breastfeeding

Contact Information
Kara Booth, Study Coordinator
Phone: (718)-920-6523
Email: KBOOTH@MONTEFIORE.ORG

PRA Partnership-Solid Tumors and Lymphomas

People with Solid Tumors and Lymphomas are asked to participate in a research study being conducted by Monter Cancer Center.

You may be eligible to participate in this study if you:
• Are a male or female at least 18 years of age
• Have histologically or cytologically confirmed advanced solid tumors or lymphoma that is metastatic or unresectable
• Have acceptable organ function

You may NOT participate in this study if you:
• Have hypersensitivity to ASTX660
• Have poor medical risk because of systemic diseases
• Have a history of, or at risk for, cardiac disease
• Have a known history of human immunodeficiency virus (HIV) infection, hepatitis B or C
• Have had prior anticancer treatments or therapies within the indicated time window prior to first dose of study treatment (ASTX660)
• Have known brain metastases unless stable or previously treated
• Are pregnant or breastfeeding

Contact Information
Carolyn Pellizzari, Study Coordinator
450 Lakeville Road, Lake Success, NY 11042
Phone: (516) 734-8921
Fax: 516-734-8909
Email: cpellizzar@northwell.edu

Rollover GlaxoSmithKline TESARO-sponsored niraparib study

People with Ovarian Cancer are asked to participate in a research study being conducted by Monter Cancer Center.

You may be eligible to participate in this study if you:
• Understand the study procedures and agrees to participate in the study by providing written informed consent.
• Are currently receiving treatment with niraparib
• Are currently benefiting from treatment with niraparib as assessed by the Investigator

You may NOT participate in this study if you:
• Have been permanently discontinued from niraparib treatment in the parent study for any reason.
• Currently have unresolved toxicities for which niraparib dosing has been interrupted in the parent study
• Are pregnant or breastfeeding

Contact Information
Mary Agnes Templeton, Study Coordinator
450 Lakeville Road
Lake Success, New York 11042
Phone: (516) 734-8979
Fax: (516) 734-8909
Email: MTEMPLETON@NORTHWELL.EDU

BESPOKE -Colorectal Cancer

People with Colorectal Cancer are asked to participate in a research study being conducted by Montefiore Medical Center.

You may be eligible to participate in this study if you:
• Are a male or female at least 18 years of age
• Are planning or undergone surgical resection of adenocarcinoma of the colon or rectum
• Are clinically eligible for adjuvant chemotherapy
• Have pathologic stage II or III disease

You may NOT participate in this study if you:
• Have pathologic evidence of distant metastases
• Have history of bone marrow or organ transplant
• Have a medical condition that would prohibit blood donation (bleeding disorder)
• Are pregnant or breastfeeding
• Have a serious medical condition

Contact Information
Cristal Garcia, Study Coordinator
1695 Eastchester Rd. Bronx, NY 10461
Phone: (718) 405-8477
Email: CRIGARCI@MONTEFIORE.ORG

Advanced Solid Tumor Malignancies

Trial Name: BGB-A1217/BGB-A317 Phase 1/1b Study Investigating Safety, Tolerability,
Pharmacokinetics and Preliminary Antitumor Activity of Anti-TIGIT Monoclonal Antibody BGB-A1217 in Combination with Anti-PD-1 Monoclonal Antibody Tislelizumab (BGB-A317) in Patients with Unresectable Locally Advanced or Metastatic Solid Tumors

People with Advanced Solid Tumor Malignancies are asked to participate in a research study being conducted by Montefiore Medical Center.

You may be eligible to participate in this study if you:
• Are a male or female at least 18 years of age
• Have histologically or cytologically confirmed unresectable locally advanced or metastatic solid tumors
• Have adequate organ function
• Have histologically or cytologically confirmed extensive-stage SCLC with no prior systemic therapy
• Have archived tumor tissue or fresh biopsy

You may NOT participate in this study if you:
• Have active leptomeningeal disease or uncontrolled brain metastasis
• Have any active malignancy
• Have history of interstitial lung disease, noninfectious pneumonitis, or uncontrolled lung diseases
• Have known immunodeficiency virus (HIV) infection, hepatitis B or C
• Had major surgery (<3 weeks prior to the first dose of study drugs) • Are pregnant or breastfeeding Contact Information Cristal Garcia, Study Coordinator 1695 Eastchester Road – Bronx, NY 10461 Phone: (718) 405-8477 Fax: (718) 405-8230 Email: crigarci@montefiore.org

Chain Tissue Implant

People with Surgical Tissue are asked to participate in a research study being conducted by Montefiore Medical Center.

You may be eligible to participate in this study if you:
• Skeletally mature adult ≥ 50 years of age at the time of surgery
• Have adequate vertebral body height and geometry for insertion of the access instruments
• VAS back pain score ≥ 70 mm on a 100 mm scale
• One- or two- level, acute (within six weeks of injury), thoracic or lumbar (T6-L5) vertebral body compression fracture(

You may NOT participate in this study if you:
• Have uncorrectable coagulopathy
• Have known history of Paget’s disease, osteomalacia, or any other metabolic bone disease
• Have an active malignancy or an active systemic or local infection
• Have degenerative scoliosis
• Have an inability to walk or stand prior to sustaining the vertebral compression fracture
• Have more than two levels with a vertebral compression fracture
• Previous instrumented spinal surgery

Contact Information
Parina Shah, Study Coordinator
Phone: (718) 920-6267
Email: PARISHAH@MONTEFIORE.ORG

EPON ph I, FIH Metastatic Gastric Cancer

People with Metastatic Gastric Cancer are asked to participate in a research study being conducted by Montefiore Medical Center.

You may be eligible to participate in this study if you:
• Are a male or female at least 18 years of age
• Have functions of important organs
• Have HER2 expression or mutation must have a pathologically documented advanced/unresectable or metastatic solid tumor that is refractory to or intolerable with standard treatment
• Have a pathologically documented advanced/unresectable or metastatic gastric or gastroesophageal junction adenocarcinoma
• Have a pathologically documented advanced/unresectable or metastatic breast cancer with HER2 low expression
• Have a pathologically documented advanced/unresectable or metastatic NSCLC with HER2 expression or mutation
• Have a pathologically documented advanced/unresectable or metastatic cancer with HER2 expression or mutation

You may NOT participate in this study if you:
• Have received mitomycin C and nitrosoureas chemotherapy within 6 weeks before first time study drug administration
• Have Active central nervous system (CNS) metastasis without surgery or radiotherapy
• Have known immunodeficiency virus (HIV) infection, hepatitis B or C
• Any surgery (eg., surgery for cancer treatment), radiotherapy, chemotherapy or molecular targeted treatment within 4 weeks
• Have a history of clinically significant lung diseases
• Have a known history of severe allergy to any component of the SHR-A1811 product
• Are pregnant or breastfeeding

Contact Information
Mohammad Ghalib, Study Coordinator
1695 Eastchester Road, 2nd Floor
Bronx, NY 10461
Phone: (718) 405-8515
Email: MHGHALIB@MONTEFIORE.ORG

Head and Neck Squamous Cell Cancer – Syneos – BioNTech

People with Squamous Cell Cancer are asked to participate in a research study being conducted by Montefiore Medical Center.

Patients may be eligible to participate in this study if they:
• Are a male or female at least 18 years of age
• Have histologically confirmed recurrent or metastatic HPV16+ HNSCC that is considered incurable
• Have adequate bone marrow & hepatic function
• Have adequate kidney function
• Can provide a tumor tissue sample

Patients may NOT participate in this study if they:
• Have known allergy, hypersensitivity, or intolerance to BNT113
• Have had a splenectomy
• Have had major surgery within 4 wks before screening
• Have known immunodeficiency virus (HIV) infection, hepatitis B or C
• Have current evidence of new or growing brain or spinal metastases
• Have had prior anti-cancer therapy
• Are pregnant or breastfeeding

Contact Information
Cristal Garcia, Study Coordinator
1695 Eastchester Rd. Bronx, NY 10461
Phone: (718) 405-8477
Email: crigarci@montefiore.org

Uterine Serous Carcinoma – Parexel – Astra Zeneca-247600

People with Uterine Serous Carcinoma are asked to participate in a research study being conducted by Montefiore Medical Center.

You may be eligible to participate in this study if you:
• Are a male or female at least 18 years of age
• Have histologically confirmed recurrent or persistent USC
• Have normal organ and marrow function at baseline
• Consent to submit and provision of a mandatory FFPE tumour sample

You may NOT participate in this study if you:
• Have an uncontrolled intercurrent illness
• Are unable to swallow oral medications
• Have known malignant central nervous system disease
• Have a known cardiac disease
• Have known immunodeficiency virus (HIV) infection, hepatitis B or C
• Are pregnant or breastfeeding

Contact Information
Natasha Rambishun, Study Coordinator
1695 Eastchester Road suite 505.
Bronx, NY 10461.
Phone: (718)-405-8396
Email: NRAMBISH@MONTEFIORE.ORG

SYMPTOMATIC HEART FAILURE HFrEF

People with Heart Failure are asked to participate in a research study being conducted by Montefiore Medical Center.

You may be eligible to participate in this study if you:
• Have LV Ejection Fraction: ≥20 to ≤40%
• Have LV end-diastolic diameter ≥55 mm

You may NOT participate in this study if you:
• Have prior mitral or aortic valve replacement
• Have untreated degenerative (primary) mitral valve disease
• Have moderate or severe aortic valve stenosis
• Have severe RV dysfunction
• Have active bacterial endocarditis

Contact Information
Angeline Camilo, Study Coordinator
Phone: (718)-920-4595
Email: ACAMILO@MONTEFIORE.ORG

Sickle Cell Disease

People with Sickle Cell Disease are asked to participate in a research study being conducted by Montefiore Medical Center.

You may be eligible to participate in this study if you:

• Are a male or female 12 to 55 years with SCA
• Hb 8.0 g/dL during screening

You may NOT participate in this study if you:
• Have anemia due to bone marrow failure
• Have severe renal dysfunction
• Have had RBC transfusion within 3 months before initiation of study drug
• Have hospitalization for VOC or acute chest syndrome
• Have had major surgery within 8 weeks before enrollment
• Have a planned elective surgery within the next 6 months
• Have known immunodeficiency virus (HIV) infection, hepatitis A, B, or C
• Are pregnant or breastfeeding

Contact Information
Jennifer De Los Santos, Study Coordinator
Phone: (718) 741-2672
Email: JENNIFER.DELOSSANTOS@EINSTEINMED.ORG

SPARO

People with a prediction of Active Rejection in Organs using donor-derived cell-free DNA detection are asked to participate in a research study being conducted by Montefiore Medical Center.

You may be eligible to participate in this study if you:
• Are a male or female 2 years old or older at the time of enrollment
• Have received at least one organ transplant prior to Enrollment

You may NOT participate in this study if you:
• Are a pediatric subject under 2 years old
• Have received donor organ from an identical twin

Contact Information
Patricia Flynn, Study Coordinator
Phone: 718) 655-1120
Email: PFLYNN@MONTEFIORE.ORG

TALAZOPARIB SOFT GEL CAPSULE FORMULATION Advanced Solid Tumors

People with Advanced Solid Tumors are asked to participate in a research study being conducted by Montefiore Medical Center.

You may be eligible to participate in this study if you:
• Are a male or female between the ages of 18 and 70
• Have histological diagnosis of recurrent, locally advanced or metastatic solid tumor
• Have adequate bone marrow, renal, and hepatic function
• Are able to swallow capsules whole without breaking apart or crushing

You may NOT participate in this study if you:
• Have had major surgery within the past 4 weeks
• Have been diagnosed with MDS or AML
• Have an active infection
• Have known or suspected brain metastasis or active leptomeningeal disease
• Have clinically significant cardiovascular disease
• Have known history of testing positive for HIV, AIDS, positive HBV surface antigen, positive HCV RNA, or positive COVID-19 viral test
• Are pregnant or breastfeeding

Contact Information
Mohammad Ghalib, Study Coordinator
1695 Eastchester Road, 2nd floor
Bronx, NY 10461
Phone: (718) 405-8515
Email: mhghalib@montefiore.org

DESTINY-Breast06 Metastatic Breast Cancer

People with metastatic breast cancer are asked to participate in a research study being conducted by Montefiore Medical Center.

You may be eligible to participate in this study if you:
• Are a male or female at least 18 years of age
• Have pathologically documented breast cancer
• Have adequate tumor tissue, organ function, and bone marrow
• Have radiological evidence of disease progression
• Have had no prior chemotherapy for advanced or metastatic breast cancer

You may NOT participate in this study if you:
• Have received prior treatment with anti-HER2 therapy
• Have uncontrolled hypertension
• Have known immunodeficiency virus (HIV) infection, hepatitis B, or hepatitis C
• Are pregnant or breastfeeding

Contact Information
Kathy Lora, Study Coordinator
1695 Eastchester Road
Bronx, NY 10461
Phone: (718) 405-8523
Email: klora@montefiore.org

Gastroesophageal Junction (GEJ) Adenocarcinoma

People with Gastroesophageal Junction (GEJ) Adenocarcinoma are asked to participate in a research study being conducted by Montefiore Medical Center.

You may be eligible to participate in this study if you:
• Are a male or female at least 18 years of age
• Have histologically confirmed diagnosis of Gastric or GEJ adenocarcinoma.
• Have radiologically evaluable disease (measurable and/or non-measurable)

You may NOT participate in this study if you:
• Have received prior systemic chemotherapy
• Have received radiotherapy
• Have had a major surgical procedure less than or 28 days prior to randomization
• Have known history of central nervous system (CNS) metastases
• Have an active infection requiring systemic therapy
• Have known immunodeficiency virus (HIV) infection, hepatitis B or C
• Are pregnant or breastfeeding

Contact Information
Cristal Garcia, Study Coordinator
1695 Eastchester Rd. Bronx, NY 10461
Phone: (718) 405-8477
Email: crigarci@montefiore.org

Biomarker Study on Tumor Tissue for Non-small Cell Lung Cancer (NSCLC)

People with non-small cell lung cancer are asked to participate in a research study being conducted by Northwell Health

You may be eligible to participate in this study if you:
• Are a male or female at least 18 years of age or older
• Have pathologically documented, locally-advanced and unresectable or metastatic NSCLC
• Have archived tumor tissue samples collected within 5 years

You may NOT participate in this study if you:
• Have known additional malignancy other than NSCLC within last 3 years
• Have known significant cardiovascular disease
• Have known history of Human Immunodeficiency Virus (HIV) Infection, Hepatitis B and Hepatitis C

Contact Information
Alexa Amoroso, Regulatory Coordinator
450 Lakeville Road, Lake Success, New York 11042
Phone: (516) 734-8977
Email: aamoroso1@northwell.edu

NSCLC Abbvie Study m14-237

People with NSCLC are asked to participate in a research study being conducted by Montefiore Medical Center.

You may be eligible to participate in this study if you:
• Are a male or female at least 18 years of age
• Have advanced NSCLC
• Have adequate renal and hepatic function
• Have a negative serum pregnancy test, if female

You may NOT participate in this study if you:
• Have received anticancer therapy
• Have known history of interstitial lung disease
• Have had major surgery within 21 days of first dose
• Have known immunodeficiency virus (HIV) infection
• Are pregnant or breastfeeding

Contact Information
Cristal Garcia, Study Coordinator
1695 Eastchester Road – Bronx, NY 10461
Phone: (718) 405-8477
Fax: (718) 405-8230
Email: crigarci@montefiore.org

Metastatic Colorectal Cancer – Medpace

People with colorectal cancer are asked to participate in a research study being conducted by Montefiore Medical Center.

You may be eligible to participate in this study if you:
• Are a male or female at least 18 years of age
• Have histological or cytological confirmation of the diagnosis of mCRC
• Adequate bone marrow, renal and hepatic function

You may NOT participate in this study if you:
• Have active cardiac disease
• Have history of vascular disease
• Have had prior chemotherapy, radiation therapy, or major surgery within past 4 weeks
• Have known immunodeficiency virus (HIV) infection or hepatitis C, or hepatitis B
• Are pregnant or breastfeeding

Contact Information
Mohammad Ghalib, Study Coordinator
1695 Eastchester Road, 2nd floor
Bronx, NY 10461
Phone: (718) 405-8515
Email: mhghalib@montefiore.org

M7824 with cCRT in Unresectable Stage III NSCLC

People with non-small cell lung cancer are asked to participate in a research study being conducted by White Plains Hospital.

You may be eligible to participate in this study if you:
• Are a male or female at least 18 years of age
• Have histologically documented NSCLC
• Have availability of tumor material
• Have adequate organ, renal, & pulmonary function

You may NOT participate in this study if you:
• Have received major surgery within the past 4 weeks
• Have significant or acute chronic infections
• Have active tuberculosis
• Have known immunodeficiency virus (HIV) infection, Hepatitis B, or Hepatitis C
• Are pregnant or breastfeeding

Contact Information
Lisa La, Study Coordinator
2 Longview Avenue White Plains, NY 10601
Phone: (914)-849-7429
Email: LLA1@WPHOSPITAL.ORG

Solid Tumors with KRAS p.G12C Mutation

People with Solid Tumor are asked to participate in a research study being conducted by Montefiore Medical Center.

You may be eligible to participate in this study if you:
• Are a male or female at least 18 years of age
• Are willing to provide tumor tissue samples
• Have the ability to take oral medications
• Pathologically documented, locally-advanced or metastatic malignancy with KRAS

You may NOT participate in this study if you:
• Have a history of malignancy within the past 2 years
• Have an active infection requiring IV antibiotics
• Have gastrointestinal tract disease causing inability to take oral medications
• Have known immunodeficiency virus (HIV) infection, hepatitis B, or hepatitis C
• Are pregnant or breastfeeding

Contact Information
Mohammad Ghalib, Study Coordinator
1695 Eastchester Road, 2nd floor
Bronx, NY 10461
Phone: (718) 405-8515
Email: mhghalib@montefiore.org

Sym021 in Combination with Either Sym022 or Sym023 in Patients with Advanced Solid Tumor Malignancies

People with Advanced Solid Tumor Malignancies are asked to participate in a research study being conducted by Montefiore Medical Center.

You may be eligible to participate in this study if you:

• Are a male or female at least 18 years of age
• Have documented (histologically or cytologically proven) unresectable, locally advanced or metastatic malignancies
• Have adequate organ function

You may NOT participate in this study if you:

• Have Central Nervous System unless treated and stable malignancies
• Have a significant cardiovascular disease, recent gastrointestinal disease, or pulmonary disease
• Have a history of organ transplant
• Have known immunodeficiency virus (HIV) infection, hepatitis B, or hepatitis C
• Are pregnant or breastfeeding

Contact Information
Mohammad Ghalib, Study Coordinator
1695 Eastchester Road, 2nd floor
Bronx, NY 10461
Phone: (718) 405-8515
Email: MHGHALIB@MONTEFIORE.ORG

Metastatic Cervical Cancer

People with cervical cancer are asked to participate in a research study being conducted by Northwell Health.

You may be eligible to participate in this study if you:

• Female at least 18 years of age
• Have histologically or cytologically confirmed recurrent or metastatic squamous carcinoma or adeno-squamous carcinoma of the cervix
• Have available archived tumor tissue sample
• Adequate organ function

You may NOT participate in this study if you:

• Have brain/central nervous system metastases
• Have active infections
• Have known immunodeficiency virus (HIV) infection, hepatitis B, or hepatitis C
• Known allergy or reaction to any component of the AK104 formulation
• Are pregnant or breastfeeding

Contact Information
Mary Agnes Templeton, Study Coordinator
450 Lakeville Road
Lake Success, NY 11042
Phone: (516) 734-8979
Email: mtempleton@northwell.edu

RELAPSED REFRACTORY LARGE B-CELL LYMPHOMA

People with Lymphoma asked to participate in a research study being conducted by Montefiore Medical Center.

You may be eligible to participate in this study if you:

  • Are a male or female at least 18 years of age
  • Have adequate renal function, liver function,
  • Normal blood oxygen saturation levels

You may NOT participate in this study if you:

  • Have known history of CNS lymphoma
  • Radiation therapy (only within two weeks of receiving investigational product per study inclusion/exclusion criteria)
  • Have any form of primary or acquired immunodeficiency
  • Have history of hypertension crisis or hypersensitive encephalopathy
  • Have active systemic bacterial, fungal, or viral infection
  • Have active or clinically significant autoimmune disease within the last 2 years.

Contact Information
Prafulla Bhagat, Study Coordinator
1695 Eastchester Road
Bronx, New  York 10461
Phone: (718) 405-8545
Email: prafulla.bhagat@einsteinmed.org

Metastatic Solid Tumors CRESTONE

People with Metastatic Solid Tumors are asked to participate in a research study being conducted by Montefiore Medical Center.

You may be eligible to participate in this study if you:

  • Are a male or female at least 18 years of age
  • Have locally-advanced or metastatic solid tumor with an NRG1 gene fusion
  • Adequate hepatic function & hematologic status
  • Have availability of fresh or archived FFPE tumor sample
  • Have at least one measurable extra-cranial lesion

You may NOT participate in this study if you:

  • Have received investigational treatment in another clinical study within the past 28 days
  • Have symptomatic or untreated brain metastases
  • Have known, actionable oncogenic driver mutation other than NRG1 fusion, where available standard therapy is indicated
  • Have an active uncontrolled systemic infection
  • Have clinically significant cardiac disease
  • Have known immunodeficiency virus (HIV) infection
  • Are pregnant or breastfeeding

Contact Information
Cristal Garcia, Regulatory Coordinator
1695 Eastchester Road – Bronx, NY 10461
Phone: (718) 405-8404
Fax: (718) 405-8433
Email:crigarci@montefiore.org

Acute Myeloid Leukemia

People with acute myeloid leukemia are asked to participate in a research study being conducted by Northwell Health.

You may be eligible to participate in this study if you:

  • Are a male or female at least 18 years of age
  • Have morphologically confirmed diagnosis of AML

You may NOT participate in this study if you:

  • Have a chronic respiratory disease
  • Have known hepatic cirrhosis
  • Have an active infection
  • Have high blood pressure
  • Have known active immunodeficiency virus (HIV) infection, hepatitis B, or hepatitis C infection
  • Are pregnant or breastfeeding

Contact Information
Christine Persuad, Study Coordinator
300 Community Drive Manhasset, NY 11030
Phone (516) 321-2253
Email: cpersaud9@northwell.edu

Metastatic Solid Tumors

People with Metastatic Solid Tumors are asked to participate in a research study being conducted by Montefiore Medical Center.

You may be eligible to participate in this study if you:

• Are a male or female at least 18 years of age
• Have a histologically or cytologically documented, advanced (metastatic and/or unresectable) cancer
• Demonstrate adequate organ function

You may NOT participate in this study if you:

• Have received treatment with systemic anticancer treatments or investigational products (IPs) within 14 days before the first dose of study drug
• Have a history of uncontrolled brain metastasis
• Have had prior treatment with TAK-981
• Have a receipt of any live vaccine
• Have an active infection
• Have known immunodeficiency virus (HIV) infection, hepatitis B or C
• Are pregnant or breastfeeding

Contact Information
Mohammad Ghalib, Study Coordinator
1695 Eastchester Road, 2nd floor
Bronx, NY 10461
Phone: (718) 405-8515
Email: mhghalib@montefiore.org

Premenopausal Females

Premenopausal Females are asked to participate in a research study being conducted by Montefiore Medical Center.

You may be eligible to participate in this study if you:

  • Are a premenopausal female, ≥18 years to 35 years of age
  • Are at risk for pregnancy with a partner who is not known to be subfertile, sterilized, or infertile
  • Do not desire a pregnancy within 24 months of enrollment
  • Are in good physical and mental health
  • Have a history of regular menstrual cycles

You may NOT participate in this study if you:

  • Have a known or suspected pregnancy or breastfeeding
  • Have a history of infertility
  • Have a history of VTE
  • Are currently using an IUD/IUS
  • Have any vaginal bleeding in the 12 months before enrollment
  • Have uncontrolled or severe hypertension
  • Have clinically significant liver disease
  • Have any disease that may worsen under hormonal treatment

Contact Information
Karina Avila, Study Coordinator
Phone: 347-573-3410
Email: kavila@montefiore.org

 

NSCLC

People with NSCLC are asked to participate in a research study being conducted by Monter Cancer Center.

You may be eligible to participate in this study if you:

  • Are a male or female at least 18 years of age
  • Have received Osimertinib and have had disease progression while on Osimertinib
  • Have advanced NSCLC that is not amenable to surgical resection or other approved therapeutic options that have demonstrated clinical benefit
  • Have adequate renal and hepatic function
  • Have adequate bone marrow function

You may NOT participate in this study if you:

  • Have had anti-cancer therapy within a period of 21 days prior to the first dose of the M14-237 study drug
  • Have known active COVID-19 infection
  • Have a history of interstitial lung disease (ILD) or pneumonitis
  • Have had major surgery within 21 days prior to the first dose of ABBV-399
  • Are pregnant or breastfeeding

Contact Information
Edison Sham, Study Coordinator
450 Lakeville Road Lake Success, NY 11042
Phone: (516) 734-7629
Email: esham@northwell.edu

 

Advanced High-Grade Epithelial Ovarian, Primary Peritoneal, or Fallopian Tube Cancers

Women with Ovarian Cancer are asked to participate in a research study being conducted by Icahn School of Medicine at Mount Sinai.

You may be eligible to participate in this study if you:

  • Are a female at least 18 years of age
  • Have a confirmed diagnosis of high-grade serous EOC, primary peritoneal cancer, or fallopian tube cancer
  • Have platinum-resistant disease
  • Have completed any major surgery at least 4 weeks prior to first dose of

MIRV and have recovered or stabilized from the side effects of prior surgery

  • Have adequate hematologic, liver and kidney functions

You may NOT participate in this study if you:

  • Have primary platinum-refractory disease
  • Have folate deficiency (take folate supplements)
  • Have active or chronic corneal disorders, history of corneal transplantation, or active ocular conditions requiring ongoing treatment/monitoring
  • Have a serious concurrent illness or clinically relevant active infection
  • Have a clinically significant cardiac disease
  • Have a history of hemorrhagic or ischemic stroke or a history of cirrhotic liver disease
  • Are pregnant or breastfeeding

Contact Information
Martina Kracikova, Study Coordinator
One Gustave L. Levy Place, Box 1170 New York, NY 10029
Phone: (212)-824-7859
Fax: (212) 824 2347
Email: martina.kracikova@mssm.edu

Peritoneal Carcinoma

People with Epithelial Ovarian, Fallopian Tube Or Peritoneal Carcinoma are asked to participate in a research study being conducted by Icahn School of Medicine at Mount Sinai.

You may be eligible to participate in this study if you:

  • Are a male or female at least 18 years of age
  • Have adequate bone marrow, renal, & liver function
  • Are newly diagnosed epithelial adenocarcinoma of ovarian, fallopian tube or peritoneal origin FIGO Stage III or IV disease

You may NOT participate in this study if you:

  • Have mucinous adenocarcinoma and low-grade adenocarcinoma
  • Have an active infection
  • Have certain cardiovascular conditions
  • Have history or evidence upon physical examination of CNS disease, seizures not controlled with standard medical therapy, or any brain metastases.
  • Have uncontrolled or life-threatening diseases
  • Have known immunodeficiency virus (HIV) infection, hepatitis B, or hepatitis C
  • Are pregnant or breastfeeding

Contact Information
Martina Kracikova, Study Coordinator
One Gustave L. Levy Place, Box 1170 New York, NY 10029
Phone: (212)-824-7859
Fax: (212) 824 2347
Email: martina.kracikova@mssm.edu

Metastatic Non-small Cell Lung Cancer (NSCLC)

People with non-small cell lung cancer are asked to participate in a research study being conducted by Northwell Health

You may be eligible to participate in this study if you:

  • Are a male or female at least 18 years of age or older
  • Have histologically or pathologically documented, locally-advanced and unresectable or metastatic NSCLC

You may not participate in this study if you:

  • Have known history of Human Immunodeficiency Virus (HIV) Infection, Hepatitis B and Hepatitis C
  • Have known additional malignancy other than NSCLC within last 3 years
  • Are pregnant, breastfeeding or plan to become pregnant

Contact Information
Alexa Amoroso, Research Coordinator
450 Lakeville Road, Lake Success, NY 11042
Phone: (516) 734-8896
Email: aamoroso1@northwell.edu

Idiopathic Intracranial Hypertension

People with Idiopathic Intracranial Hypertension are asked to participate in a research study being conducted by North Shore University Hospital.

You may be eligible to participate in this study if you:

  • Are a male or female at least 18 years of age
  • Have a diagnosis of IIH per Modified Dandy Criteria
  • Have a venographic evidence of sinus stenosis
  • Have a presence of IIH clinical symptoms
  • Have a CSF opening pressure is > 25 cm H2O

You may NOT participate in this study if you:

  • Are allergic to nitinol or nickel
  • Have a contra-indication to general anesthesia
  • Have a contra-indication to aspirin, clopidogrel or other anticoagulant
  • History of severe COPD or other severe respiratory disease.
  • History of deep vein thrombosis or pulmonary embolism.
  • History of AF or other risks of stroke
  • History of uncontrolled diabetes.
  • Are pregnant or breastfeeding

Contact Information
Israel Mahr, Study Coordinator
Phone: (631) 806-9568

Email: IMahr@northwell.edu

Active Lupus Nephritis

People with Active Lupus Nephritis are asked to participate in a research study being conducted by The Feinstein Institutes for Medical Research.

You may be eligible to participate in this study if you:

  • Are a male or female at least 18-75 years of age
  • Have active lupus nephritis
  • Have confirmed diagnosis of SLE
  • Are on one cholesterol-lowering agents
  • Are willing to be treated with anti-malarials

You may NOT participate in this study if you:

  • Have history of chronic, recurrent systemic infections, active tuberculosis infection or active systemic infections
  • Have active ongoing inflammatory diseases
  • Have history of renal transplant
  • Have severe renal impairment
  • Have known history of lymphoproliferative disease or any known malignancy history
  • Have known immunodeficiency virus (HIV) infection, hepatitis B or C
  • Are pregnant or breastfeeding

Contact Information
Andrew Shaw, Study Coordinator
Phone: 516-562-2591

Email: anshaw@northwell.edu

Advanced Non-Squamous Non-Small Cell Lung Cancer

People with advanced non-squamous, non-small cell lung cancer are asked to participate in a research study being conducted by Northwell Health

You may be eligible to participate in this study if you:

• Are a male or female 18 years of age or older
• Are in receipt of prior first-line treatment with a platinum based chemotherapy regimen
• Have had your most recent prior therapy discontinued at least 2 weeks before the date of on-study treatment

You may NOT participate in this study if you:

• Have active or prior documented autoimmune disease
• Have known human immunodeficiency virus (HIV), Hepatitis B and Hepatitis C
• Are pregnant, breastfeeding or plan to become pregnant

Contact Information
Alexa Amoroso, Regulatory Coordinator
450 Lakeville Road, Lake Success, NY 11042
Phone: (516) 734-8977
Fax: (516) 734-8909
Email: aamoroso1@northwell.edu

Locally advanced or metastatic breast cancer

People with breast cancer are asked to participate in a research study being conducted by Montefiore Medical Center.

You may be eligible to participate in this study if you:

  • Are a male or female at least 18 years of age
  • Have histologically or cytologically documented advanced breast cancer
  • Have adequate bone marrow, renal, and liver function

You may NOT participate in this study if you:

  • Have received 4 or more regimens of chemotherapy for metastatic breast cancer
  • Have known history of cardiac valve disease or active inflammatory gastrointestinal disease
  • Have known immunodeficiency virus (HIV) infection, hepatitis B, or hepatitis C
  • Have had major surgery within 4 weeks of first study drug dose
  • Have an acute or chronic severe medical or psychiatric condition

Contact Information
Priscilla Vazquez, Study Coordinator
1695 Eastchester Road
Bronx, New York 10461
Phone: (718) 405-8578

Email: pvazquez@montefiore.org

 

Darolutamide roll-over study

People with cancer are asked to participate in a research study being conducted by Montefiore Medical Center.

You may be eligible to participate in this study if you:

  • Are a male or female at least 18 years of age
  • Are enrolled in any Bayer-sponsored darolutamide feeder study at the time of study closure or primary completion, who are currently receiving darolutamide and are experiencing clinical benefit from the treatment

You may NOT participate in this study if you:

  • Have negative benefit/risk ratio as determined by investigator
  • Meet any criteria for treatment discontinuation of the feeder study that you are coming from
  • Are pregnant or breastfeeding

Contact Information
Mary Portes, Study Coordinator
1695 Eastchester Road Bronx, NY 10461
Phone: (718) 405-8209
Email: mportes@montefiore.org

Relapsed Refractory Large B-Cell Lymphoma

People with Lymphoma asked to participate in a research study being conducted by Montefiore Medical Center.

You may be eligible to participate in this study if you:

  • Are a male or female at least 18 years of age
  • Have adequate renal function, liver function,
  • Normal blood oxygen saturation levels

You may NOT participate in this study if you:

  • Have known history of CNS lymphoma
  • Radiation therapy
  • Have any form of primary or acquired immunodeficiency
  • Have history of hypertension crisis or hypersensitive encephalopathy
  • Have active systemic bacterial, fungal, or viral infection
  • Have active or clinically significant autoimmune disease within the last 2 years.

Contact Information
Prafulla Bhagat, Study Coordinator
1695 Eastchester Road
Bronx, New  York 10461
Phone: (718) 405-8545
Email: prafulla.bhagat@einsteinmed.org

 

Advanced unresectable Urothelial Cancer – GSK – IQVIA EPON

People with Urothelial Cancer are asked to participate in a research study being conducted by Icahn School of Medicine at Mount Sinai.

You may be eligible to participate in this study if you:

  • Are a male or female at least 18 years of age
  • Have Histologically confirmed locally advanced or metastatic or locally advanced/unresectable urothelial carcinoma
  • Able to provide, a tumor tissue sample

You may NOT participate in this study if you:

  • Have active brain and/or leptomeningeal disease
  • Have history of malignancy other than urothelial cancer within the last 3 years
  • Have cirrhosis or current unstable liver or biliary disease
  • Have an active infection
  • Have a history of bleeding diathesis
  • Have known immunodeficiency virus (HIV) infection, hepatitis B, or hepatitis C
  • Are pregnant or breastfeeding

Contact Information
Philip Garcia, Clinical Research Coordinator
1 Gustave Levy Place Box 1128
New York, NY 10029
Phone: (212) 824-7312
Email: pHILIP.GARCIA@MSSM.EDU

Phase 1 – Solid Tumors

People with solid tumors are asked to participate in a research study being conducted by Montefiore Medical Center.

You may be eligible to participate in this study if you:

  • Are a male or female at least 18 years of age
  • Have histologically or cytologically documented, locally-advanced or metastatic solid tumors
  • Have adequate kidney function
  • Have archived tumor biopsy available

You may NOT participate in this study if you:

  • Have a preexisting autoimmune disease, heart disease, or rapidly progressive disease
  • Have known immunodeficiency virus (HIV) infection, hepatitis B, or hepatitis C
  • Have serious cardiac illness
  • Have known alcohol or drug abuse
  • Are pregnant or breastfeeding

Contact Information
Mohammad Ghalib, Study Coordinator
1695 Eastchester Road, 2nd Floor
Bronx, New York 10461
Phone: (718) 405-8515
Email: mhghalib@montefiore.org

Metastatic breast cancer

People with unresectable and/or metastatic breast cancer that is human epidermal growth factor receptor 2 (HER2)-low are asked to participate in a research study being conducted by Montefiore Medical Center.

You may be eligible to participate in this study if you:

  • Are a male or female at least 18 years of age
  • Have unresectable or metastatic breast cancer
  • Have been treated with 1 to 2 prior lines of chemotherapy

You may NOT participate in this study if you:

  • Have a cardiovascular disease
  • Have participated in a radiation therapy or had major surgery within 4 weeks of treatment
  • Have known immunodeficiency virus (HIV) infection, hepatitis B or C infection, or any active infection
  • Are pregnant or breastfeeding

Contact Information
Kathy Lora, Study Coordinator
1695 Eastchester Road
Bronx, NY 10461
Phone: (718) 405-8523
Email: klora@montefiore.org

 

Severe Mucositis in Head and Cancer Patients

People with head and neck cancer are asked to participate in a research study being conducted by Montefiore Medical Center.

You may be eligible to participate in this study if you:

  • Are a male or female at least 18 years of age
  • Have medically diagnosed head or neck cancer
  • Adequate organ function
  • Must be receiving cisplatin for chemotherapy

You may NOT participate in this study if you:

  • Have received prior chemotherapy
  • Have inability to swallow and/or eat soft or solid food
  • Have suffered from oral diseases
  • Have known immunodeficiency virus (HIV) infection, hepatitis B, or hepatitis C
  • Are pregnant or breastfeeding

Contact Information
Sarah Yukelis, Study Coordinator
111 E. 210th Street Bronx, NY 10467
Phone: (718)-920-2301
Email: syukelis@montefiore.org

Acute Myelogenous Leukemia or Myelodysplastic Syndrome

People with acute myelogenous leukemia are asked to participate in a research study being conducted by Montefiore Medical Center.

You may be eligible to participate in this study if you:

  • Are a male or female at least 18 years of age
  • Have adequate organ function
  • Have the ability to swallow or retain oral medications

You may NOT participate in this study if you:

  • Have received major surgery or chemotherapy treatment in past 14 days
  • Have been diagnosed with acute promyelocytic or CNS leukemia
  • Have known cardiovascular disease or gastrointestinal disease
  • Have fungal, viral, or bacterial infection
  • Have known immunodeficiency virus (HIV) infection, Hepatitis B, or Hepatitis C
  • Are pregnant or breastfeeding

Contact Information
Prafulla Bhagat, Study Coordinator
1695 Eastchester Road Room 225
Bronx, New York 10467
Phone: (718) 405-8545

Email: prafulla.bhagat@einsteinmed.org

 

Patients Relapsed Refractory Leukemias

People with relapsed/refractory leukemias are asked to participate in a research study being conducted by Montefiore Medical Center

You may be eligible to participate in this study if you:

  • Are a male or female 18 years of age or older

You may NOT participate in this study if you:

  • Have known human immunodeficiency virus (HIV), Hepatitis B and Hepatitis C
  • Are pregnant, breastfeeding or plan to become pregnant

Contact Information
Prafulla Bhagat, Regulatory Coordinator
111 East 210th Street, Bronx, NY 10467
Phone: 718-405-8545
Email: pbhagat@montefiore.org

Advanced and Recurrent Solid Tumors

People with solid tumors are asked to participate in a research study being conducted by Montefiore Medical Center.

You may be eligible to participate in this study if you:

  • Are a male or female at least 18 years of age
  • Have advanced or metastatic solid tumors and have completed first line therapy.
  • Evidence of disease progression
  • Adequate organ function

You may NOT participate in this study if you:

  • Have received chemotherapy within 28 days of the start of study
  • Have an active infection
  • Have known immunodeficiency virus (HIV) infection, hepatitis B, or hepatitis C
  • Are pregnant or breastfeeding

Contact Information
Cristal Garcia, Study Coordinator
1695 Eastchester Rd. Bronx, NY 10461
Phone: (718)- 405-8477
Email: crigarci@montefiore.org

Atezolizumab In Combination With Cabozantinib

People with Renal Cell Carcinoma are asked to participate in a research study being conducted by Montefiore Medical Center.

You may be eligible to participate in this study if you:

  • Are a male or female at least 18 years of age
  • Have confirmed locally advanced or metastatic renal cell carcinoma
  • Have adequate organ function

You may NOT participate in this study if you:

  • Have received major surgery within the past 4 weeks
  • Severe infection within 4 weeks prior to initiation of study
  • Have history of leptomeningeal disease or active tuberculosis
  • Have known immunodeficiency virus (HIV) infection, hepatitis B, or hepatitis C
  • Are pregnant or breastfeeding

Contact Information
Mary Portes, BS, Study Coordinator
Clinical Trials Manager
Oncology Services Montefiore Medical Park
Medical Oncology Green Glass Building (MMP)
1695 Eastchester Road 2nd Floor
Bronx, NY 10461
T: 718-405-8427 F: 718-405-8433
Email: mportes@montefiore.org

Subjects with Solid Tumors

People with Solid Tumors are asked to participate in a research study being conducted by Montefiore Medical Center.

You may be eligible to participate in this study if you:

  • Are a male or female at least 18 years of age
  • Have adequate organ function
  • Have fresh and/or archival tumor tissue

You may NOT participate in this study if you:

  • Received cancer treatment or live vaccine within 28 days prior to first dose
  • Had major surgery, still unhealed, within 28 days prior to first dose
  • History of lung disease or pneumonia
  • Have known history of autoimmune disease
  • Have known immunodeficiency virus (HIV) infection
  • Are pregnant or breastfeeding

Contact Information
Mohammad Ghalib, Study Coordinator
111 E. 210th Street
Bronx, New York 10467
Telephone:718-405-8515
Email: mhghalib@montefiore.org

High-Risk Non-Muscle-Invasive Bladder Cancer

People with bladder cancer are asked to participate in a research study being conducted by Montefiore Medical Center.

You may be eligible to participate in this study if you:

  • Are a male or female at least 18 years of age
  • Have histologically confirmed, recurrent, non-muscle-invasive bladder cancer
  • Have adequate bone marrow, liver, and renal function
  • Have a negative pregnancy test, if female

You may NOT participate in this study if you:

  • Have T2 stage or higher bladder cancer
  • Have uncontrolled cardiovascular disease or active malignancies other than bladder cancer
  • Have known immunodeficiency virus (HIV) infection, hepatitis B, or hepatitis C
  • Have had major surgery within 4 weeks of Cycle 1
  • Are pregnant or breastfeeding

Contact Information
Mary Portes, BS, Study Coordinator
1695 Eastchester Road
Bronx, NY 10461
Phone: 405-8427
Fax: 718-405-8433
Email: mportes@montefiore.org

Receptor 2 negative (HR+/HER2-) breast cancer – Astra Zeneca

People with breast cancer are asked to participate in a research study being conducted by Monter Cancer Center.

You may be eligible to participate in this study if you:

  • Are a male or female at least 18 years of age
  • Have histologically confirmed HR/HER2-breast cancer
  • Can swallow and retain oral medication

You may NOT participate in this study if you:

  • Have received major surgery within the past 4 weeks
  • Have inadequate bone marrow reserve or organ function
  • Have evidence of dementia
  • Have known immunodeficiency syndrome
  • Are pregnant or breastfeeding

Contact Information
Mary Agnes Templeton, Study Coordinator
450 Lakeville Road Lake Success, NY 11042
Phone: (516) 734-8979
Email: mtempleton@northwell.edu

Metastatic Cervical Cancer

People with cervical cancer are asked to participate in a research study being conducted by Icahn School of Medicine at Mount Sinai.

You may be eligible to participate in this study if you:

  • Female at least 18 years of age
  • Adequate organ function
  • ECOG Performance Status of 0 or 1

You may NOT participate in this study if you:

  • Have concurrent enrollment in another study
  • Have active infections
  • Have known immunodeficiency virus (HIV) infection, hepatitis B, or hepatitis C
  • Have cancer spread into brain/central nervous system

Contact Information
Martina Kracikova, Study Coordinator
One Gustave L. Levy Place, Box 1170 New York, NY 10029
Phone: (212)-824-7859
Fax: (212) 824 2347
Email: martina.kracikova@mssm.edu

Advanced and Recurrent Endometrial Cancer (DUO-E)

People with cancer are asked to participate in a research study being conducted by Icahn School of Medicine at Mount Sinai.

You may be eligible to participate in this study if you:

  • Are a male or female at least 18 years of age
  • Have histologically confirmed diagnosis of epithelial endometrial carcinoma
  • Have adequate organ & bone marrow function
  • Have endometrial cancer that is newly diagnosed Stage III disease, newly diagnosed Stage IV disease, or have recurrence of disease.

You may NOT participate in this study if you:

  • Have received a major surgical procedure in within 2 weeks of starting study treatment
  • Have known history of allogenic organ transplantation
  • Have an active infection
  • Have known immunodeficiency virus (HIV) infection, hepatitis B, or hepatitis C
  • Are pregnant or breastfeeding

Contact Information
Martina Kracikova, Study Coordinator
One Gustave L. Levy Place, Box 1170 New York, NY 10029
Phone: (212)-824-7859
Fax: (212) 824 2347
Email: martina.kracikova@mssm.edu

HER2-Positive Gastric or Gastroesophageal Junction Cancer

People with gastroesophageal junction cancer are asked to participate in a research study being conducted by Queens Hospital Center.

You may be eligible to participate in this study if you:

  • Are a male or female at least 18 years of age
  • Have histologically confirmed diagnosis of untreated locally advanced unresectable or metastatic HER2+ GC
  • Have adequate organ function

You may NOT participate in this study if you:

  • Have received investigational treatment in another clinical study within the past 4 weeks
  • Have had major surgery within 4 weeks prior to start of study treatment
  • Have any serious underlying medical or psychiatric condition
  • Have known immunodeficiency virus (HIV) infection, hepatitis B, hepatitis C, or hepatitis D with B
  • Are pregnant or breastfeeding

Contact Information
Linda Bulone, RN Study Coordinator
82-68 164th St.
Jamaica, NY 11432
Phone: (718) 883-3751
Email: bulonel@NYCHHC.org

TIRAGOLUMAB PLUS ATEZOLIZUMAB AND ATEZOLIZUMAB MONOTHERAPY

Women with cervical cancer are asked to participate in a research study being conducted by Icahn School of Medicine at Mount Sinai.

You may be eligible to participate in this study if you:

  • Are a female at least 18 years of age
  • Stage IVB, recurrent or persistent cervical cancer
  • After at least 1 line of prior therapy
  • Adequate hematologic and organ function
  • No active infection

You may NOT participate in this study if you:

  • Have planned surgery during the study
  • Have active tuberculosis or leptomeningeal disease
  • Have known immunodeficiency virus (HIV) infection, hepatitis B, or hepatitis C
  • Are pregnant or breastfeeding

Contact Information
Martina Kracikova, Study Coordinator
One Gustave L. Levy Place, Box 1170
New York, NY 10029
Phone: (212) 824-7859
Email: Martina.kracikova@MSSM.EDU

Chronic Lymphocytic Leukemia / Small Lymphocytic Lymphoma (C/SLL) or Non-Hodgkin Lymphoma (NHL)

People with previously treated Lymphomas are asked to participate in a research study being conducted by Northwell Health.

You may be eligible to participate in this study if you:

  • Are a male or female at least 18 years of age
  • Have historically confirmed B-cell malignancy
  • Have adequate liver function

You may NOT participate in this study if you:

  • Have known central nervous system (CNS) involvement by systemic lymphoma
  • Have had major surgery within 4 weeks of study start
  • Have known immunodeficiency virus (HIV) infection
  • Are pregnant or breastfeeding

Contact Information
Dina Padula, Study Coordinator
410 Lakeville Road, Suite 212
New Hyde Park, NY, 11042
Telephone: 718-470-4745
Fax: 516-470-4250
Email: dpadula1@northwell.edu

Patients with Neurofibromatosis Type 1 (NF1)

People with neurofibromatosis are asked to participate in a research study being conducted by Montefiore Medical Center.

Your child may be eligible to participate in this study if he/she:

  • Are a male or female at least 2 years of age or older
  • Has a clinical diagnosis of neurofibromatosis (NF1)
  • Has the ability to swallow capsules whole

Your child may not participate in this study if he/she:

  • Has a history of malignancy associated hypercalcemia
  • Has any clinically significant active or known history of liver disease, or known hepatic or biliary abnormalities
  • Has a history of a positive human immunodeficiency virus (HIV)
  • Has received radiation therapy within the past 6 months

Contact Information
Annette Pedro, Study Coordinator
111 East 210th Street
Bronx, New York 10467
Phone: (718) 741-2356
Email: APEDRO@montefiore.org

Relapsed/refractory hematologic malignancies

People with hematologic malignancies are asked to participate in a research study being conducted by Northwell Health.

You may be eligible to participate in this study if you:

• Are a male or female 18 to 85 years of age
• Have diagnosis of hematologic malignancies
• Have received at least 2 prior lines of therapy for the treatment of current histology

You may not participate in this study if you:

• Have had major surgery within the past 4 weeks
• Have known immunodeficiency virus (HIV) infection, hepatitis B or hepatitis C
• Are pregnant or breastfeeding

Contact Information
Christine Pun, Study Coordinator
450 Lakeville Road
Lake Success, New York 11042
Phone: (516) 734-8920
Email: FPUN@NORTHWELL.EDU

NON-SMALL CELL LUNG CANCER -Skyscraper 03

People with non-small cell lung cancer are asked to participate in a research study being conducted by Montefiore Medical Center.

You may be eligible to participate in this study if you:

  • Are a male or female at least 18 years of age
  • Adequate hematolgic and end-organ function
  • Show no progression during or following concurrent platinum-based CRT
  • Have at least two prior cycles of chemotherapy

You may NOT participate in this study if you:

  • Have received major surgery within the past 4 weeks prior to initiation
  • Have an active infection
  • Have active tuberculosis, liver disease, or cardiovascular disease
  • Have known immunodeficiency virus (HIV) infection, hepatitis B, or hepatitis C
  • Are pregnant or breastfeeding

Contact Information
Cristal Garcia, Study Coordinator
1695 Eastchester Road – Bronx, NY 10461
Phone: (718) 405-8477
Fax: (718) 405-8230
Email: crigarci@montefiore.org

REAL registry PI3K-inhibitors

People with lymphoma are asked to participate in a research study being conducted by Queens Hospital Center.

You may be eligible to participate in this study if you:

  • Are a male or female at least 18 years of age
  • Have clinically or pathological diagnosis of chronic lymphocytic leukemia (CLL) / small lymphocytic lymphoma (SLL)
  • Are willing to provide a signed & dated IRB approved Informed Consent Form

You may NOT participate in this study if you:

  • Not applicable

Contact Information
Rayhana Dhulkifl, MD, Study Coordinator
82-68 164th Street
Jamaica, NY 11432
Phone: (718) 883-3797
Email: DHULKIFR@nychhc.org

Biochemical recurrence of prostate cancer – Parexel #245597

People with prostate cancer are asked to participate in a research study being conducted by Queens Hospital Center.

You may be eligible to participate in this study if you:

  • Are a male at least 18 years of age
  • Previously took ADT, should be discontinued at least 16 weeks prior to screening
  • Are a patient with history of localized prostate cancer with prior curative treatment
  • Have an elevated prostate-specific antigen (PSA)

You may NOT participate in this study if you:

  • Have prior medical condition that may compromise data collection
  • Are currently receiving ADT
  • Are planning to have an x-ray prior to PET scan
  • Are participating in a clinical trial within 30 days of administration

Contact Information
Linda Bulone, Study Coordinator
82-68 164th Street Room A541 Jamaica, NY 11432
Phone: (718) 883-3751
Fax: (718) 883-6295
Email: bulonel@nychhc.org

Biomarker Study on Tumor Tissue for Non-small Cell Lung Cancer (NSCLC)

People with non-small cell lung cancer are asked to participate in a research study being conducted by Montefiore Medical Center

You may be eligible to participate in this study if you:

  • Are a male or female at least 18 years of age or older
  • Have pathologically documented, locally-advanced and unresectable or metastatic NSCLC
  • Have archived tumor tissue samples collected within 5 years

You may NOT participate in this study if you:

  • Have known additional malignancy other than NSCLC within last 3 years
  • Have known significant cardiovascular disease
  • Have known history of Human Immunodeficiency Virus (HIV) Infection, Hepatitis B and Hepatitis C

Contact Information
Cristal Garcia, Regulatory Coordinator
1695 Eastchester Road – Bronx, NY 10461
Phone: (718) 405-8404
Fax: (718) 405-8433
Email:   crigarci@montefiore.org

Adults with cold Agglutinin Disease

People with Agglutinin Disease are asked to participate in a research study being conducted by Montefiore Medical Center.

You may be eligible to participate in this study if you:

  • Are a male or female at least 18 years of age with Coronary Artery Disease (CAD)
  • Covered by health insurance system
  • Hemoglobin level ≤11 mg/dL

You may NOT participate in this study if you:

  • Clinical diagnosis of Lupus
  • Have known history of liver disease or Gilbert’s disease
  • Hypersensitivity to BIVV020
  • Have known immunodeficiency virus (HIV) infection, hepatitis B, or hepatitis C
  • Are pregnant or breastfeeding

Contact Information
Hieu Nguyen, Study Coordinator
1300 Morris Park Ave, Ullmann Building Rm 921
Bronx, NY 10461
Phone: (718)- 430-2748
Fax: (718) 430-8855
Email: hinguyen@montefiore.org

Multiple Myeloma

People with multiple myeloma are asked to participate in a research study being conducted by Montefiore Medical Center.

You may be eligible to participate in this study if you:

  • Are a male or female 18 to 79 years of age
  • Have newly diagnosed multiple myeloma

You may not participate in this study if you:

  • Have gastrointestinal disease that may significantly alter the absorption of oral drugs
  • Have had major surgery within the past 2 weeks
  • Have known immunodeficiency virus (HIV) infection, hepatitis B or hepatitis C
  • Are pregnant, breastfeeding or plan to become pregnant

Contact Information
Prafulla Bhagat, Study Coordinator
111 East 210th Street Bronx NY 10467
Phone: (718) 405-8545
Email: pbhagat@montefiore.org

Advanced EGFR-positive Solid Tumor Malignancies

People with tumors are asked to participate in a research study being conducted by Montefiore Medical Center.

You may be eligible to participate in this study if you:

  • Are a male or female at least 18 years of age
  • Have a confirmed solid tumor
  • Have archival tumor tissue available

You may NOT participate in this study if you:

  • Have received major surgery within the past 4 weeks
  • Have cardiovascular disease
  • Have significant infections
  • Have known immunodeficiency virus (HIV) infection, hepatitis B, or hepatitis C
  • Are pregnant or breastfeeding

Contact Information

Imran Chaudhary, Study Coordinator
1695 Eastchester Road, Bronx, NY 10461
Phone: (718)- 405-8542
Email: ichaudha@montefiore.org

Stage III Non-Small Cell Lung Cancer (NSCLC)

People with non-small cell lung cancer are asked to participate in a research study being conducted by Montefiore Medical Center.

You may be eligible to participate in this study if you:

  • Are a male or female at least 18 years of age
  • Have confirmed NSCLC
  • Have adequate organ function
  • Have no evidence of metastatic disease

You may NOT participate in this study if you:

  • Have received investigational treatment in another clinical study within the past 4 weeks or had major surgery within the past 4 weeks
  • Have known history of tuberculosis
  • Have known immunodeficiency virus (HIV) infection, Hepatitis B, or Hepatitis C
  • Are pregnant or breastfeeding

Contact Information
Cristal Garcia, Study Coordinator
1695 Eastchester Road – Bronx, NY 10461
Phone: (718) 405-8477
Fax: (718) 405-8230
Email: crigarci@montefiore.org

Metastatic Non-small Cell Lung Cancer (NSCLC)

People with non-small cell lung cancer are asked to participate in a research study being conducted by Montefiore Medical Center

You may be eligible to participate in this study if you:

  • Are a male or female at least 18 years of age or older
  • Have histologically or pathologically documented, locally-advanced and unresectable or metastatic NSCLC

You may not participate in this study if you:

  • Have known history of Human Immunodeficiency Virus (HIV) Infection, Hepatitis B and Hepatitis C
  • Have known additional malignancy other than NSCLC within last 3 years
  • Are pregnant, breastfeeding or plan to become pregnant

Contact Information
Cristal Garcia, Regulatory Coordinator
1695 Eastchester Road – Bronx, NY 10461
Phone: (718) 405-8404
Fax: (718) 405-8433
Email:   crigarci@montefiore.org

Metastatic Non-small Cell Lung Cancer (NSCLC)

People with non-small cell lung cancer are asked to participate in a research study being conducted by Montefiore Medical Center

You may be eligible to participate in this study if you:

  • Are a male or female at least 18 years of age or older
  • Have histologically or pathologically documented, locally-advanced and unresectable or metastatic NSCLC

You may not participate in this study if you:

  • Have known history of Human Immunodeficiency Virus (HIV) Infection, Hepatitis B and Hepatitis C
  • Have known additional malignancy other than NSCLC within last 3 years
  • Are pregnant, breastfeeding or plan to become pregnant

Contact Information
Cristal Garcia, Regulatory Coordinator
1695 Eastchester Road – Bronx, NY 10461
Phone: (718) 405-8404
Fax: (718) 405-8433
Email:   crigarci@montefiore.org

Newly diagnosed prostate cancer

People with newly diagnosed prostate cancer are asked to participate in a research study being conducted by NYC Health +Hospitals

You may be eligible to participate in this study if you:

  • Is a male more than 18 years of age
  • Have confirmed adenocarcinoma of the prostate

You may NOT participate in this study if you:

  • Currently or in the past received hormone therapy treatment for prostate cancer

Contact Information
Rayhana Dhulkifl, RN., Clinical Trial Manger
82-68 164th Street
Jamaica NY 11432
Phone: (718) 883-3797
Email:   DHULKIFR@nychhc.org

Advanced Solid Tumors and Pancreatic Cancer

People with advanced solid tumors and pancreatic cancer are asked to participate in a research study being conducted by Northwell Health

You may be eligible to participate in this study if you:

  • Are a male or female at least 18 years of age or older
  • Have histologically confirmed advanced bladder cancer, melanoma, non-small cell lung cancer, pancreatic cancer, colorectal cancer, gastric cancer, esophageal cancer, ovarian cancer, and head neck squamous cell carcinoma

You may not participate in this study if you:

  • Are using a pacemaker, implantable cardiac defibrillator or cochlear implants
  • Have tested positive for Human Immunodeficiency Virus (HIV) Infection
  • Are pregnant, breastfeeding or plan to become pregnant

Contact Information
Sarah Davis, Phase 1 Supervisor
450 Lakeville Road, Lake Success, NY  11042
Phone: (516) 734-7632
Fax: (516) 734-8909
Email: sdavis22@northwell.edu

INDUCE-3 – Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma

People with Head and Neck Squamous Cell Carcinoma are asked to participate in a research study being conducted by Montefiore Medical Center.

You may be eligible to participate in this study if you:

  • Are a male or female at least 18 years of age
  • Have adequate organ function
  • Have historical documentation of incurable or recurrent Head and Neck Squamous Cell Carcinoma

You may NOT participate in this study if you:

  • Have unstable liver
  • Have known history of tuberculosis
  • Have known immunodeficiency virus (HIV) infection, hepatitis B, or hepatitis C.
  • Are pregnant or breastfeeding

Contact Information
Cristal Garcia, Study Coordinator
Phone: (718) 405-8477
Email: crigarci@montefiore.org

B-cell Malignancies – Covance

People with B-cell Malignancies are asked to participate in a research study being conducted by Icahn School of Medicine at Mount Sinai.

You may be eligible to participate in this study if you:
• Are a male or female at least 18 years of age
• Have documented B-cell malignancies

You may NOT participate in this study if you:
• Have received major surgery within the past 4 weeks
• History of stroke or bleeding inside the skull
• Have clinically significant cardiovascular disease
• Have known immunodeficiency virus (HIV) infection, hepatitis B, or hepatitis C
• Are pregnant or breastfeeding

Contact Information
Monica Toscano, Study Coordinator
Phone: (212) 824-8333
Email: MONICA.TOSCANO@MSSM.EDU

Human Papillomavirus

People with human papillomavirus are asked to participate in a research study being conducted by Montefiore Medical Center.

You may be eligible to participate in this study if you:

  • Are a male or female at least 18 years of age or older
  • Have confirmed diagnosis of human papillomavirus

You may not participate in this study if you:

  • Have received a live vaccine within the past 28 days
  • Have tested positive for immunodeficiency virus (HIV) infection, hepatitis B or hepatitis C
  • Are pregnant or breastfeeding

Contact Information
Mohammad Ghalib, Study Coordinator
1695 Eastchester Road, 2nd floor
Bronx, NY 10461
Phone: (718) 405-8515
Email: mhghalib@montefiore.org

 

Metastatic Squamous or Non-Squamous Non-Small Cell Lung Cancer

People with non-small cell lung cancer are asked to participate in a research study being conducted by Montefiore Medical Center.

You may be eligible to participate in this study if you:

  • Are a male or female at least 18 years of age or older
  • Have histologically or cytologically confirmed stage IV squamous or non-squamous non-small cell lung cancer

You may not participate in this study if you:

  • Have an ongoing different primary malignancy
  • Have known immunodeficiency virus (HIV) infection, hepatitis B or hepatitis C
  • Are pregnant or breastfeeding

Contact Information
Cristal Garcia, Study Coordinator
1695 Eastchester Road, 2nd floor
Bronx, New York 10461
Phone: 718-405-8477
Email: crigarci@montefiore.org

FIGHT-302 – Cholangiocarcinoma

People with Cholangiocarcinoma are asked to participate in a research study being conducted by Icahn School of Medicine at Mount Sinai.

You may be eligible to participate in this study if you:

  • Are a male or female at least 18 years of age or older
  • Have histologically or cytologically confirmed cholangiocarcinoma that is previously untreated and considered unresectable and/or metastatic

You may not participate in this study if you:

  • Have had radiation therapy administered within the past 4 weeks
  • Have known CNS metastases or history of uncontrolled seizures
  • Have known additional malignancy that is progressing or requires active treatment
  • Are pregnant, breastfeeding or plan to become pregnant

Contact Information
John Botzler, Clinical Research Nurse
One Gustave L. Levy Place, Box 1120
New York, NY 10029
Phone: (212) 824-7379
Email: john.botzler@mssm.edu

CheckMate 7A8 – ER+/HER2- Breast Cancer

People with breast cancer are asked to participate in a research study being conducted by Montefiore Medical Center.

You may be eligible to participate in this study if you:

  • Are a male or female at least 18 years of age or older
  • Have histologically confirmed unilateral invasive breast carcinoma

You may not participate in this study if you:

  • Have received a live/attenuated vaccine within the past 30 days
  • Have known immunodeficiency virus (HIV) infection, hepatitis B or hepatitis C
  • Are pregnant or breastfeeding

Contact Information
Priscilla Vazquez, Study Coordinator
1695 Eastchester Road
Bronx, New York 10461
Phone: (718) 405-8578
Email: pvazquez@montefiore.org

BCG Naïve Non-Muscle Invasive Bladder Cancer

People with bladder cancer are asked to participate in a research study being conducted by Montefiore Medical Center.

You may be eligible to participate in this study if you:

  • Are a male or female at least 18 years of age or older

Have histological confirmed diagnosis of high-risk, non-muscle invasive transitional cell carcinoma of the urothelium of the urinary bladder

You may not participate in this study if you:

  • Have evidence of muscle-invasive, locally advanced or metastatic urothelial cancer or concurrent extravesical, non-muscle invasive TCC of the urothelium
  • Have received any prior radiation therapy to the bladder
  • Have received any treatment with systemic anti-cancer therapy including investigational agents within last 4 weeks
  • Have received a live vaccine within the past 4 weeks
  • Have presence of hepatitis B surface antigen or hepatitis C antibody
  • Are pregnant or breastfeeding

Contact Information

Mary Portes, Study Coordinator
1695 Eastchester Road
Bronx, NY 10461
Phone: (718) 405-8209
Fax: (718) 405-8433
Email: mportes@montefiore.org

 

19-06-395 / TX233888

 

 

 

CARTITUDE-2-Multiple Myeloma

People with multiple myeloma are asked to participate in a research study being conducted by Montefiore Medical Center.

You may be eligible to participate in this study if you:

  • Are a male or female at least 18 years of age or older
  • Have documented diagnosis of multiple myeloma

You may not participate in this study if you:

  • Have been diagnosed or treated for invasive malignancy other than multiple myeloma
  • Have had a stroke or seizure within the past 6 months
  • Have known immunodeficiency virus (HIV) infection, hepatitis B or hepatitis C
  • Are pregnant or breastfeeding

Contact Information

Saman Sarraf, Study Coordinator
111 E 210th Street
Bronx, New York 10467
Phone: (718) 920-4554
Email: saman.sarraf@einsteinmed.org

 

19-06-313 / TX233889

Hematological Malignancies

People with hematological malignancies are asked to participate in a research study being conducted by Albert Einstein College of Medicine.

You may be eligible to participate in this study if you:

  • Are a male or female at least 18 years of age or older
  • Have been diagnosed with hematological malignancies

You may not participate in this study if you:

  • Have known inherited or acquired bleeding disorders
  • Have known immunodeficiency virus (HIV) infection, hepatitis B or hepatitis C
  • Are pregnant or breastfeeding

Contact Information

Prafulla Bhagat, Research Coordinator/Data Manager
Montefiore Medical Center
1695 Eastchester Road, 2nd Floor, Room 225
Bronx, New York 10461
Phone: (718) 405-8545
Email: pbhagat@montefiore.org

 

19-06-347 / TX233890

 

Men with Metastatic Prostate Cancer

Men with metastatic prostate cancer are asked to participate in a research study being conducted by Montefiore Medical Center.

You may be eligible to participate in this study if you:

  • Are a male at least 18 years of age or older
  • Have been diagnosed with Stage IV prostate cancer
  • Are willing to provide a saliva or blood sample for genomic analysis

Contact Information

Mary Portes, Study Coordinator
1695 Eastchester Road Bronx, NY 10461
Phone: (718) 405-8209
Email: mportes@montefiore.org

 

19-08-346 / TX233891

Castration-Resistant Prostate Cancer

People with castration-resistant prostate cancer are asked to participate in a research study being conducted by Montefiore Medical Center.

You may be eligible to participate in this study if you:

  • Are a male least 18 years of age or older
  • Have histologically or cytologically confirmed adenocarcinoma of prostate

You may not participate in this study if you:

  • Have known metastatic brain or meningeal tumors
  • Have uncontrolled clinically significant hypertension
  • Have known immunodeficiency virus (HIV) infection, active viral hepatitis or chronic liver disease

Contact Information

Mary Portes, Study Coordinator
1695 Eastchester Road
Bronx, New York 10461
Phone: 718-405-8209
Email: mportes@montefiore.org

 

19-06-359 / TX233892

FIGHT-101 – Advanced Malignancies

People with advanced malignancies are asked to participate in a research study being conducted by Montefiore Medical Center.

You may be eligible to participate in this study if you:

  • Are a male or female at least 18 years of age or older
  • Have any advanced solid tumor malignancy
  • Have moderate renal impairment and severe renal impairment

You may not participate in this study if you:

  • Have had treatment with another investigational study drug or receipt of anticancer medications within the past 28 days
  • Have history of human immunodeficiency virus infection, hepatitis B or hepatitis C
  • Have active autoimmune disease requiring systemic immunosuppression in excess of physiologic maintenance doses of corticosteroids
  • Are pregnant, breastfeeding or plan to become pregnant

Contact Information

Imran Chaudhary, Study Coordinator
1695 Eastchester Road, 2st Floor
Bronx, NY 10461
Phone: 718-405-8542
Fax: 718-405-8527
Email: ichaudha@montefiore.org

 

19-06-028 / TX233887

 

JAVELIN IL-2 Medley

People with solid tumors are asked to participate in a research study being conducted by Montefiore Medical Center.

You may be eligible to participate in this study if you:

  • Are a male or female at least 18 years of age or older
  • Have histological diagnosis of solid tumors

You may not participate in this study if you:

  • Have known history of: immune-mediated colitis, inflammatory bowel disease, pneumonitis, or pulmonary fibrosis.
  • Have had a live vaccine within the past 4 weeks
  • Have history of immunodeficiency virus (HIV) infection, hepatitis B or hepatitis C
  • Are pregnant or breastfeeding

Contact Information

Imran Chaudhary, Study Coordinator
1695 Eastchester Road, 2st Floor
Bronx, NY 10461
Phone: (718) 405-8542
Fax: (718) 405-8527
Email: ichaudha@montefiore.org
19-06-256 / TX228658

Advanced Urothelial Carcinoma

People with advanced urothelial carcinoma are asked to participate in a research study being conducted by Montefiore Medical Center.

You may be eligible to participate in this study if you:

  • Are a male or female at least 18 years of age or older
  • Have histologically or cytologically confirmed urothelial carcinoma of the renal pelvis, ureter, bladder or urethra

You may not participate in this study if you:

  • Have had major surgery within the past 4 weeks
  • Have known immunodeficiency virus (HIV) infection, hepatitis B or hepatitis C
  • Are pregnant or breastfeeding

Contact Information

Mary Portes, Study Coordinator
1695 Eastchester Road
Bronx, New York 10461
Phone: (718) 405-8209
Email: mportes@montefiore.org

 

19-06-317 / TX228659

Advanced Prostate Cancer

People with advanced prostate cancer are asked to participate in a research study being conducted by White Plains Hospital.

You may be eligible to participate in this study if you:

  • Are a male at least 18 years of age or older
  • Have documented evidence of metastatic castration resistant prostate cancer
  • Are able to swallow and retain oral medication

You may not participate in this study if you:

  • Have had major surgery (excluding placement of vascular access) within the past 4 weeks
  • Have had radiotherapy with a wide field of radiation within the past 4 weeks
  • Have active infection including hepatitis B, hepatitis C and human immunodeficiency virus

Contact Information

Joel Victor, Study Coordinator
2 Longview Avenue
White Plains, New York 10601
Phone: (914) 849-7591
Fax: (914) 681-2972
Email: jvictor1@wphospital.org

 

 

19-06-195 / TX228661

Warm autoimmune haemolytic anemia (wAIHA)

People with warm autoimmune hemolytic anemia are asked to participate in a research study being conducted by Montefiore Medical Center.

You may be eligible to participate in this study if you:

  • Are a male or female at least 18 years of age or older
  • Have been diagnosed with active primary or secondary warm autoimmune hemolytic anemia

You may not participate in this study if you:

  • Have received a transfusion within the past 30 days
  • Have received a live vaccine within the past 3 months
  • Have known history of HIV, hepatitis B or hepatitis C
  • Are pregnant or breastfeeding

Contact Information

Hieu Nguyen, Study Coordinator
1300 Morris Park Ave, Ullmann Building Rm 921
Bronx, NY 10461
Phone: (718) 430-2748
Fax: (718) 430-8855
Email: hinguyen@montefiore.org

 

19-02-312 / TX228660

Autoimmune Hemolytic Anemia and Immune Thrombocytopenia

People with autoimmune hemolytic anemia and immune thrombocytopenia are asked to participate in a research study being conducted by Montefiore Medical Center.

You may be eligible to participate in this study if you:

  • Are a male or female at least 18 years of age or older
  • Have documented diagnosis of hemolytic anemia and immune thrombocytopenia

You may not participate in this study if you:

  • Have had major surgery within the past 12 months
  • Have a history of any hereditary anemia
  • Have a history of primary immunodeficiency
  • Are pregnant or breastfeeding

Contact Information

Hieu Liem L. Nguyen, Study Coordinator
1300 Morris Park Ave
Ullmann Building Rm 921
Bronx, NY, 10461
Phone: (718)430-2748
Fax: (718)430-8855
Email: hinguyen@montefiore.org

 

19-02-240 / TX228662

Cutaneous Squamous Cell Carcinoma

People with cutaneous squamous cell carcinoma are asked to participate in a research study being conducted by Northwell Health, Inc.

You may be eligible to participate in this study if you:

  • Are a male or female at least 18 years of age or older
  • Have pathologically confirmed cutaneous squamous cell carcinoma

You may not participate in this study if you:

  • Have received a live vaccine within the past 28 days
  • Have human immunodeficiency virus (HIV), hepatitis B or hepatitis C virus
  • Are pregnant or breastfeeding

Contact Information

Sigal Bein, Study Coordinator
Monter Cancer Center
450 Lakeville Road
Lake Success, NY 11042
Phone: 516-734-7767
Email: sbein@northwell.edu

 

 

TX228663

 

IIT-Uterine Serous Carcinoma

People with uterine serous carcinoma are asked to participate in a research study being conducted by Northwell Health Inc.

You may be eligible to participate in this study if you:

  • Are a female at least 18 years of age or older
  • Have histologically diagnosis of uterine serous carcinoma

You may not participate in this study if you:

  • Have had major surgery within the past 3 weeks
  • Have known active hepatitis disease
  • Are pregnant or breastfeeding

Contact Information

Mary Agnes Templeton, Study Coordinator
450 Lakeville Road
Lake Success, New York 11042
Phone: (516) 734-8979
Email: mtempleton@northwell.edu

 

19-06-278 / TX228668

TALAPRO-2

People with prostate cancer are asked to participate in a research study being conducted by Montefiore Medical Center.

You may be eligible to participate in this study if you:

  • Are a male or female at least 18 years of age or older, 20 years old if Japan
  • Have histologically or cytologically confirmed adenocarcinoma of the prostate without small cell or signet cell features

You may not participate in this study if you:

  • Have received investigational treatment in another clinical study within the past 4 weeks
  • Have had prior treatment with opioids for pain related to either primary prostate cancer or metastasis within the past 28 days
  • Have clinically significant cardiovascular disease

Contact Information

Mary Portes, Study Coordinator
1695 Eastchester Road
Bronx, New York 10461
Phone: 718-405-8209
Email: mportes@montefiore.org

 

19-06-268 / TX228665

Sickle Cell Disease Expanded Access Program

People with sickle cell disease are asked to participate in an expanded access program being conducted by Queens Hospital Center. This program is for patients with Sickle Cell Disease who have no other treatment options and would allow you access to a drug that is not yet commercially available.

You/your child may be eligible to participate in this study if you or your child:

  • Are a male or female at least 12 years of age older
  • Have documented diagnosis of sickle cell disease of any genotype

You/your child may not participate in this study if you/your child:

  • Have participated in another clinical trial of an investigational agent (or medical device) within the past 30 days
  • Have known immunodeficiency virus (HIV) infection, hepatitis B or hepatitis C
  • Are pregnant or breastfeeding

Contact Information

Linda Bulone, Study Coordinator
82-68 164th St. A-541, New Building, 5th Floor
Jamaica, NY 11432
Phone: (718) 883-3751
Email:bulonel@nychhc.org

 

19-10-242 / TX228677

Sickle Cell Diseases Trial

People with sickle cell disease are asked to participate in a research study being conducted by Montefiore Medical Center.

You/your child may be eligible to participate in this study if you or your child:

  • Are a male or female at least 12 years of age older
  • Have documented diagnosis of sickle cell disease of any genotype

You/your child may not participate in this study if you/your child:

  • Have participated in another clinical trial of an investigational agent (or medical device) within the past 30 days
  • Have known immunodeficiency virus (HIV) infection, hepatitis B or hepatitis C
  • Are pregnant or breastfeeding

Contact Information

Shuo You, Study Coordinator
1521 Jarrett Place, 2nd Floor
Bronx, New York 10461
Phone: (718) 430-2123
Email: shuo.you@einstein.yu.edu

 

>19-10-242 / TX228675

Non-Small Cell Lung Cancer

People with non-small cell lung cancer are asked to participate in a research study being conducted by Montefiore Medical Center.

You may be eligible to participate in this study if you:

  • Are a male or female at least 20 years of age or older
  • Have histologically or cytologically confirmed diagnosis of non-small cell lung cancer

You may not participate in this study if you:

  • Have received investigational product from another clinical study within the past 30 days
  • Have a history of myocardial infarction or unstable angina within the past 6 months
  • Have known immunodeficiency virus (HIV) infection, hepatitis B or hepatitis C
  • Are pregnant or breastfeeding

Contact Information

Remy Lambert, Study Coordinator
1695 Eastchester Road
Bronx, New York 10461
Phone: (718) 405-8027
Email: rlambert@montefiore.org

 

19-06-267 / TX228680

HER2 Negative Advanced Breast Cancer

People with HER2 negative advanced breast cancer are asked to participate in a research study being conducted by Queens Hospital Center.

You may be eligible to participate in this study if you:

  • Are a female at least 18 years of age or older
  • Have histological or cytological proven diagnosis of adenocarcinoma of the breast

You may not participate in this study if you:

  • Have had major surgery within the past 4 weeks
  • Have evidence of either locally advanced not amenable to radiation therapy or surgery in a curative intent, and/or metastatic disease
  • Have any other cancer

Contact Information

Linda Bulone, Study Coordinator
82-68 164th Street Room A541
Jamaica, New York 11432
Phone: (718) 883-3751
Email: BULONEL@NYCHHC.ORG

 

19-06-224 / TX228681

REVEAL 2

People with cervical intraepithelial lesions are asked to participate in a research study being conducted by Montefiore Medical Center.

You may be eligible to participate in this study if you:

  • Are a female at least 18 years of age or older
  • Have confirmed cervical infection with HPV types 16 and/or 18

You may not participate in this study if you:

  • Have a history of previous therapeutic HPV vaccination
  • Have cervical lesion(s) that cannot be fully visualized on colposcopy due to extension high into cervical canal
  • Have had any non-study, non-live vaccine within the past 2 weeks
  • Are pregnant, breastfeeding or plan to become pregnant

Contact Information

Melissa Hudson, Study Coordinator
1695 Eastchester Road, Suite L4
Bronx, New York 10461
Phone: (718) 405-8358
Email: MEHUDSON@montefiore.org

 

 

19-11-176 /  TX228682

Advanced Malignancies – Neovia

People with advanced malignancies are asked to participate in a research study being conducted by Montefiore Medical Center.

You may be eligible to participate in this study if you:

  • Are a male or female at least 18 years of age older
  • Have pathologically confirmed advanced malignancy for which standard therapy proven to provide clinical benefit does not exist or is no longer effective

You may not participate in this study if you:

  • Have uncontrolled congestive heart failure
  • Have had radiotherapy within the past 28 days
  • Have known immunodeficiency virus (HIV) infection or active viral hepatitis
  • Are pregnant or breastfeeding

Contact Information

Mohammad Ghalib, Study Coordinator
1695 Eastchester Road
Bronx, New York 10461
Phone: (718) 405-8515
Email: mhghalib@montefiore.org

19-06-098 / TX228683

Levodopa Induced Dyskinesia

People with Dyskinesia due to their Parkinson’s disease medication are asked to participate in a research study being conducted by Icahn School of Medicine at Mount Sinai.

You may be eligible to participate in this study if you:

  • Are a male or female patients between 30 and 85 years of age
  • Have a diagnosis of Parkinson Disease consistent with the UK Parkinson’s Disease Society
  • Have dyskinesia due to the medication taken for Parkinson’s Disease

You may not participate in this study if you:

  • Have a diagnosis of atypical parkinsonism
  • Have a history of severe depression, psychosis or hallucinations within 6 months prior to screening
  • Are pregnant or breastfeeding

Contact Information

Study Coordinator
Christina Rosario
Icahn School of Medicine at Mount Sinai
5 East 98th Street
New York, NY 10029-6574
Telephone: (212) 241-5329
Email: christina.rosario@mssm.edu

 

 

19-02-161 / TX228654

Expanded Access Protocol – migraines

People with migraines are asked to participate in a research study being conducted by Montefiore Medical Center.

You may be eligible to participate in this study if you:

  • Are a male or female at least 18 years of age or older
  • Have completed any BHV3000 (rimegepant) clinical study, without significant protocol violations

You may not participate in this study if you:

  • Have uncontrolled hypertension or uncontrolled diabetes
  • Have a history with current evidence of uncontrolled, unstable or recently diagnosed cardiovascular disease
  • Have a history of HIV disease, hepatitis B or hepatitis C
  • Are pregnant or breastfeeding

Contact Information

Daniel Sun, Study Coordinator
1250 Waters Place – Tower 2
Bronx, New York 10461
Phone: (929) 263-3831
Email: dansun@montefiore.org

19-02-244 / TX228655

SOLOIST-HF

People with type 2 diabetes post worsening heart failure are asked to participate in a research study being conducted by Montefiore Medical Center.

You may be eligible to participate in this study if you:

  • Are a male or female at least 18 years of age or older
  • Have confirmed diagnosis of type 2 diabetes

You may not participate in this study if you:

  • Have had acute coronary syndromes within the past 3 months
  • Have a history of stroke within the past 3 months
  • Have a history of dialysis within the past 1 year

Contact Information

Kairee Navarro, Study Coordinator
1825 Eastchester Road
Bronx, New York 10461
Phone: (718) 904-2067
Email: knavarro@montefiore.org

19-02-215 / TX228656

Idiopathic Hypersomnia

People with idiopathic hypersomnia are asked to participate in a research study being conducted by Montefiore Medical Center.

You may be eligible to participate in this study if you:

  • Are a male or female between 18 and 75 years of age
  • Have a primary diagnosis of idiopathic hypersomnia

You may not participate in this study if you:

  • Have a history of periodic limb movement disorder
  • Have a history of seizures, excluding early childhood non-pathological febrile seizures
  • Are pregnant, breastfeeding or plan to become pregnant

Contact Information

Mariana Figuera Losada, Study Coordinator
5501 Old York Road, Korman Ground Floor
Philadelphia, PA 19141
Phone: (718) 920-2880
Email: mfiguera@montefiore.org

 

19-02-151 / TX228657

Advanced Breast Cancer with Visceral Metastases

People with advanced breast cancer are asked to participate in a research study being conducted by White Plains Hospital.

You may be eligible to participate in this study if you:

  • Are a female at least 18 years of age or older
  • Have confirmed HR+, HER2- recurrent, locally advanced, unresectable or metastatic breast cancer
  • Are able to swallow tablets

You may not participate in this study if you:

  • Have received a live vaccination within the past 28 days
  • Have known active and clinically relevant bacterial or fungal infection, or detectable viral infection (for example, human immunodeficiency virus or viral hepatitis)
  • Are pregnant, breastfeeding or plan to become pregnant

Contact Information

Joel Victor, Study coordinator
2 Longview Avenue
White Plains, New York 10601
Phone: (914) 849-7591
Email: jvictor1@wphospital.org

 

19-06-219 / TX226746

HER2-negative advanced breast cancer

People with HER2 negative advanced breast cancer are asked to participate in a research study being conducted by Montefiore Medical Center.

You may be eligible to participate in this study if you:

  • Are an adult female at least 18 years of age or older
  • Have advanced (loco-regionally recurrent or metastatic) breast cancer not amenable to curative therapy

You may not participate in this study if you:

  • Have had major surgery within the past 14 days
  • Are concurrently using other anti-cancer therapy
  • Have known immunodeficiency virus (HIV) infection, hepatitis B or hepatitis C
  • Are pregnant, breastfeeding or plan to become pregnant

Contact Information

Kathy Lora, Study Coordinator
1695 Eastchester Road
Bronx, New York 10461
Phone: (718) 405-8523
Email: klora@montefiore.org

 

19-06-136 / TX226745

CALLA – Cervical Cancer

People with cervical cancer are asked to participate in a research study being conducted by Northwell Health.

You may be eligible to participate in this study if you:

  • Are a female at least 18 years of age older
  • Have histologically confirmed cervical adenocarcinoma, cervical squamous carcinoma, or cervical adenosquamous carcinoma

You may not participate in this study if you:

  • Have diagnosis of small cell (neuroendocrine) histology cervical cancer
  • Have have undergone a previous hysterectomy, including a supracervical hysterectomy, or will have hysterectomy as part of their initial cervical cancer therapy
  • Have known immunodeficiency virus (HIV) infection, Hepatitis B or Hepatitis C
  • Are pregnant or breastfeeding

Contact Information

Mary Agnes Templeton, Study Coordinator
450 Lakeville Road
Lake Success, NY 11042
Phone: 516-734-8979
Email: mtempleton@northwell.edu

 

19-06-071 / TX226744

LEAP-001 endometrial carcinoma

People with endometrial carcinoma are asked to participate in a research study being conducted by Icahn School of Medicine at Mount Sinai.

You may be eligible to participate in this study if you:

  • Are a female at least 18 years of age or older
  • Have Stage III, Stage IV, or recurrent, histologically-confirmed endometrial carcinoma

You may not participate in this study if you:

  • Have a known additional malignancy (other than endometrial carcinoma) that is progressing or has required active treatment in the last 3 years
  • Have significant cardiovascular impairment within the past 12 months
  • Have known immunodeficiency virus (HIV) infection, hepatitis B or hepatitis C
  • Are pregnant or breastfeeding

Contact Information

Meghan Ruiz, Study Coordinator
Mount Sinai Chelsea
325 West 15th Street
New York, New York 10011
Phone: 212 367 1863
Email: meghan.ruiz@mountsinai.org

 

19-06-199 / TX226743

Advanced Solid Tumors

People with solid tumors are asked to participate in a research study being conducted by Montefiore Medical Center.

You may be eligible to participate in this study if you:

  • Are a male or female at least 18 years of age or older
  • Have confirmed locally-advanced (unresectable) or metastatic solid tumor malignancy

You may not participate in this study if you:

  • Have received a live vaccine within the past 28 days
  • Have an active autoimmune disease
  • Have positive Hepatitis B virus antibodies and surface antigen (indicating acute HBV or chronic HBV) or Hepatitis C
  • Are pregnant or breastfeeding

Contact Information

Mohammad Ghalib, Study Coordinator
1695 Eastchester Road, 2nd Floor
Bronx, New York 10461
Phone: (718) 405-8515
Email: mhghalib@montefiore.org

19-06-134 / TX226742

BRAFV600E-mutant Non-small Cell Lung Cancer

People with non-small cell lung cancer are asked to participate in a research study being conducted by Montefiore Medical Center.

You may be eligible to participate in this study if you:

  • Are a male or female at least 18 years of age or older
  • Have histologically confirmed diagnosis of non-small cell lung cancer that is currently Stage IV
  • Are able to swallow, retain and absorb oral medications

You may not participate in this study if you:

  • Have had major surgery within the past 6 weeks
  • Have known immunodeficiency virus (HIV) infection, active hepatitis B or hepatitis C
  • Are pregnant, breastfeeding or plan to become pregnant

Contact Information

Remy Lambert, Study Coordinator
1695 Eastchester Road
Bronx, New York 10461
Phone: (718) 405-8027
Email: rlambert@montefiore.org

 

 

19-06-138 / TX226741

TocAtez-Lung

People with non-small cell lung cancer are asked to participate in a research study being conducted by Northwell Health.

You may be eligible to participate in this study if you:

  • Are a male or female at least 18 years of age older
  • Have histologically or cytologically confirmed non-small cell lung cancer

You may not participate in this study if you:

  • Have had a severe infection within the past 4 weeks
  • Have active or latent tuberculosis
  • Have hepatitis B virus (HBV) infection, hepatitis C virus (HCV) infection or HIV
  • Are pregnant, breastfeeding or plan to become pregnant

Contact Information

Sarah Davis, Study Coordinator
450 Lakeville Road
Lake Success, New York 11042
Phone: 516-734-7632
Email: sdavis22@northwell.edu
 

19-06-062 / TX226754

Ovarian Cancer (OVATION 2)

People with advanced epithelial ovarian, fallopian tube or primary peritoneal cancer are asked to participate in a research study being conducted by Northwell Health.

You may be eligible to participate in this study if you:

  • Are a female at least 18 years of age or older
  • Have histologic diagnosis of epithelial ovarian, fallopian tube, or primary peritoneal carcinoma

You may not participate in this study if you:

  • Have received prior chemotherapy for any abdominal or pelvic tumor
  • Are receiving treatment for active autoimmune disease such as systemic lupus erythematosus, multiple sclerosis, inflammatory bowel disease and rheumatoid arthritis
  • Have known hepatitis
  • Are pregnant or breastfeeding

Contact Information

Sarah Davis, Study Coordinator
Monter Cancer Center
450 Lakeville Road
Lake Success, New York 11042
Phone: (516) 734-7632
Email: sdavis22@northwell.edu

19-11-175 / TX226752

 

Advanced Solid Tumors

People with advanced solid tumors are asked to participate in a research study being conducted by Northwell Health.

You may be eligible to participate in this study if you:

  • Are a male or female at least 18 years of age or older
  • Have histologic or cytologic confirmation of advanced solid tumor with the exception of ocular melanoma and hepatocellular carcinoma
  • Have received and have progressed on or be refractory to at least 1 line of standard systemic therapy in the recurrent/metastatic setting

You may not participate in this study if you:

  • Have moderate or severe cardiovascular disease
  • Have had major surgery within the past 4 weeks
  • Have known immunodeficiency virus (HIV) infection, active hepatitis B or hepatitis C
  • Are pregnant, breastfeeding or plan to become pregnant

Contact Information

Sarah Davis, Research Manager
450 Lakeville Road
Lake Success, NY 11042
Phone: 516-734-7632
Email:  sdavis22@northwell.edu

 

19-06-090 / TX226751

PACIFIC-4/RTOG-3515 – Non-Small Cell Lung Cancer

People with non-small cell lung cancer are asked to participate in a research study being conducted by Montefiore Medical Center.

You may be eligible to participate in this study if you:

  • Are a male or female at least 18 years of age or older
  • Have histologically or cytologically documented Stage I to II non-small cell lung cancer

You may not participate in this study if you:

  • Have mixed small cell and non-small cell cancer histology
  • Have hypothyroidism (eg, following Hashimoto syndrome) stable on hormone replacement
  • Have active infection including tuberculosis, hepatitis B, hepatitis C or human immunodeficiency virus (HIV)
  • Are pregnant or breastfeeding

Contact Information

Alyssa Asaro, Study Coordinator
111 E. 210TH Street
Bronx, New York 10467
Phone: (718) 920-2396
Email: AASARO@MONTEFIORE.ORG

 

19-06-141 / TX226750

PANOVA-3 Pancreatic Adenocarcinoma

People with pancreatic adenocarcinoma are asked to participate in a research study being conducted by White Plains Hospital.

You may be eligible to participate in this study if you:

  • Are a male or female 18 years of age or older
  • Have histological/cytological diagnosis of de novo adenocarcinoma of the pancreas

You may not participate in this study if you:

  • Have had prior palliative treatment (surgery, radiation) to the tumor
  • Have implantable electronic medical devices in the torso, such as a pacemaker
  • Are pregnant, breastfeeding or plan to become pregnant

Contact Information

Catherine Reilly, MPH, RN, Clinical Research Nurse
2 Longview Avenue
White Plains, New York 10601
Phone: (914) 849-7515
Email: creilly@wphospital.org

 

19-06-158 / TX226749

Multiple Myeloma

People with multiple myeloma are asked to participate in a research study being conducted by Northwell Health.

You may be eligible to participate in this study if you:

  • Are a male or female 18 to 79 years of age
  • Have newly diagnosed multiple myeloma

You may not participate in this study if you:

  • Have gastrointestinal disease that may significantly alter the absorption of oral drugs
  • Have had major surgery within the past 2 weeks
  • Have known immunodeficiency virus (HIV) infection, hepatitis B or hepatitis C
  • Are pregnant, breastfeeding or plan to become pregnant

Contact Information

Shirly Gholian, Study Coordinator
450 Lakeville Road
Lake Success, NY 11042
Phone: (516) 734-7217
Email: sgholian@northwell.edu

 

 

19-06-180 / TX226747

Biliary Tract Cancer

People with biliary tract cancer are asked to participate in a research study being conducted by Northwell Health.

You may be eligible to participate in this study if you:

  • Are a male or female at least 18 years of age or older
  • Have histopathologically or cytologically-confirmed, unresectable, locally advanced, recurrent, or metastatic biliary tract cancer

You may not participate in this study if you:

  • Have myocardial infarction within the past 6 months
  • Have received any investigational agent or study treatment within the past 30 days
  • Have evidence of brain metastases
  • Are pregnant or breastfeeding

Contact Information
Sigal Bein, Study Coordinator
450 Lakeville Road
Lake Success, New York 11042
Phone: 516-734-8812
Email: sbein@northwell.edu

 

FIGHT-302 – Cholangiocarcinoma

People with Cholangiocarcinoma are asked to participate in a research study being conducted by White Plains Hospital.

You may be eligible to participate in this study if you:

  • Are a male or female at least 18 years of age or older
  • Have histologically or cytologically confirmed cholangiocarcinoma that is previously untreated and considered unresectable and/or metastatic

You may not participate in this study if you:

  • Have had radiation therapy administered within the past 4 weeks
  • Have known CNS metastases or history of uncontrolled seizures
  • Have known additional malignancy that is progressing or requires active treatment
  • Are pregnant, breastfeeding or plan to become pregnant

Contact Information
Catherine Reilly, MPH, RN, Clinical Research Nurse
2 Longview Avenue
White Plains, New York 10601
Phone: (914) 849-7515
Email: CReilly@wphospital.org

FLT3 Mutated Acute Myeloid Leukemia

People with acute myeloid leukemia are asked to participate in a research study being conducted by Montefiore Medical Center.

You may be eligible to participate in this study if you:

  • Are a male or female between the ages of 18 and 60
  • Have a confirmed diagnosis of acute myeloid leukemia

You may not participate in this study if you:

  • Have had prior treatment of acute myeloid leukemia, except hydroxyurea or leukapheresis
  • Have severe liver disease
  • Have active infection such as hepatitis B or hepatitis C
  • Are pregnant or breastfeeding

Contact Information
Ambar Baez, Study Coordinator
111 East 210th Street
Bronx, New York 10467
Phone: 718-920-2006
Email: abaez@montefiore.org

Non-small cell lung cancer PACIFIC-4/RTOG-3515

People with non-small cell lung cancer are asked to participate in a research study being conducted by Northwell Health Inc.

You may be eligible to participate in this study if you:

  • Are a male or female at least 18 years of age or older
  • Have histologically or cytologically documented Stage I to II non-small cell lung cancer

You may not participate in this study if you:

  • Have received live attenuated vaccine within the past 30 days
  • Have active infection including tuberculosis, human immunodeficiency virus (HIV) infection, hepatitis B or hepatitis C
  • Are pregnant, breastfeeding or plan to become pregnant

Contact Information
Taylor DaSilva, Study Coordinator
Monter Cancer Center
450 Lakeville Road
Lake Success, New York 11042
Phone: (516) 734-3589
Fax #: (516) 734-8909
Email: tdasilva@northwell.edu

FIGHT-101 – Advanced Malignancies

People with advanced malignancies are asked to participate in a research study being conducted by Northwell Health.

You may be eligible to participate in this study if you:

  • Are a male or female at least 18 years of age or older
  • Have any advanced solid tumor malignancy
  • Have moderate renal impairment and severe renal impairment

You may not participate in this study if you:

  • Have had treatment with another investigational study drug or receipt of anticancer medications within the past 28 days
  • Have history of human immunodeficiency virus infection, hepatitis B or hepatitis C
  • Have active autoimmune disease requiring systemic immunosuppression in excess of physiologic maintenance doses of corticosteroids
  • Are pregnant, breastfeeding or plan to become pregnant

Contact Information
Sarah Davis, Study Coordinator
450 Lakeville Road
Lake Success, New York 11042
Phone: 516- 734-7632
Email: sdavis22@northwell.edu

Pediatric Hyperparathyroidism & Chronic Kidney Disease

Children with Secondary Hyperparathyroidism & Chronic Kidney Disease are asked to participate in a research study being conducted by Icahn School of Medicine at Mount Sinai.

Your child may be eligible to participate in this study if your child:

  • Is a male or female 28 days to less than18 years of age at the time of enrollment
  • Has been diagnosed with Chronic Kidney Disease and Secondary Hyperparathyroidism and is currently undergoing hemodialysis

Your child may not participate in this study if your child:

  • Has a history of other malignancy, except non-melanoma skin cancers, cervical or breast ductal carcinoma in situ within the last 5 years
  • Has an anticipated or scheduled kidney transplant during the 27 week  study period
  • Is pregnant or breast feeding

Contact Information
Jeanna Johnson, Study Coordinator
One Gustave L. Levy Place
New York, New York 10029
Phone: (212) 241-0488
Email: Jeanna.zalsos-johnson@mssm.edu

Small Cell Neuroendocrine Prostate Cancer

People with small cell neuroendocrine prostate cancer are asked to participate in a research study being conducted by White Plains Hospital.

You may be eligible to participate in this study if you:

  • Are a male at least 18 years of age or older
  • Have histologic evidence of small cell neuroendocrine prostate cancer

You may not participate in this study if you:

  • Have clinically significant cardiovascular disease
  • Have clinically significant uncontrolled pulmonary disease
  • Have known positive status for human immunodeficiency virus active or chronic Hepatitis B or Hepatitis C

Contact Information
Joel Victor, Study Coordinator
2 Longview Avenue
White Plains, New York 10601
Phone: (914) 849-7591
Email: jvictor1@wphospital.org

Platinum-Resistant Ovarian Cancer

A Study of Tisotumab Vedotin for Patients With Platinum-Resistant Ovarian Cancer With a Safety Run-in of a Dose-Dense Regimen (innovaTV 208)

Women with platinum resistant ovarian cancer are asked to participate in a research study being conducted by Icahn School of Medicine at Mount Sinai.

You may be eligible to participate in this study if you:

  • Are a female at least 18 years of age or older
  • Have histologic documentation of epithelial ovarian cancer, primary peritoneal cancer, or fallopian tube cancer

You may not participate in this study if you:

  • Have primary platinum-refractory disease, defined as disease progression within 2 months of completion of first line platinum-based therapy
  • Have had gastrointestinal obstruction within the past 6 months or who currently require parenteral nutrition
  • Have known past or current coagulation defects leading to an increased risk of bleeding
  • Have clinically significant cardiac disease
  • Have active ocular surface disease
  • Have ongoing, acute, or chronic inflammatory skin disease
  • Have uncontrolled tumor-related pain
  • Have Inflammatory lung disease requiring chronic medical therapy
  • Have Grade 3 or higher pulmonary disease unrelated to underlying malignancy
  • Have Grade >1 peripheral neuropathy
  • Have inflammatory bowel disease including Crohn’s disease and ulcerative colitis
  • Are pregnant, breastfeeding or plan to become pregnant

Contact Information
Martina Kracikova, PhD, Study Coordinator
One Gustave L. Levy Place, Box 1170
New York, New York 10029
Phone: 212 824 7859
Email: martina.kracikova@mssm.edu

LUCENT 1

People with ulcerative colitis are asked to participate in a research study being conducted by Northwell Health.

You may be eligible to participate in this study if you:

  • Are a male or female ages 18-80
  • Have had an established diagnosis of moderate to severe ulcerative colitis 3 or more months in duration
  • Have not been helped by previous or current treatments

You may not participate in this study if you:

  • Have a known history of human immunodeficiency virus (HIV), Hepatitis B or Hepatitis C
  • Have any history or current evidence of cancer of the gastrointestinal tract
  • Are pregnant, breastfeeding or plan to become pregnant

Contact Information
Keith Sultan, MD
600 Northern Blvd, Suite 111
Great Neck, New York 11021
Phone: (516) 387-3912
Email: GIRESEARCH@northwell.edu

Solid Tumors

People with solid tumors are asked to participate in a research study being conducted by Icahn School of Medicine at Mount Sinai.

You may be eligible to participate in this study if you:

  • Are a male or female at least 18 years of age, nut not more than 75
  • Have histologically or cytologically documented, locally-advanced or metastatic solid malignancy of any type

You may not participate in this study if you:

  • Have received investigational treatment in another clinical study within the past 4 weeks
  • Have known history of liver disease, including viral or other hepatitis or cirrhosis
  • Have known immunodeficiency virus (HIV) infection
  • Are pregnant or breastfeeding

Contact Information
Jennifer Perez, Study Coordinator
One Gustave L. Levy Place
New York, New York 10029
Phone: (212) 824-7303
Email: jennifer.perez2@mssm.edu

Focal Segmental Glomerulosclerosis

People with focal segmental glomerulosclerosis are asked to participate in a research study being conducted by New York University School of Medicine.

You may be eligible to participate in this study if you:

  • Are male or female aged 8 to 75 years old within the U.S.
  • Are male or female aged 18 to 75 years old outside of the U.S.
  • Have had biopsy-proven primary focal segmental glomerulosclerosis

You may not participate in this study if you:

  • Have FSGS secondary to another condition
  • Have a history of type 1 diabetes mellitus or uncontrolled type 2 diabetes mellitus
  • Have participated in a study of another investigational product within the past 28 days
  • Are pregnant, breastfeeding or planning to become pregnant

Contact Information

Suzanne Vento, Study Coordinator
227 East 30th Street
New York, New York 10016
Phone: (646) 501-2665
Email: Suzanne.Vento@nyumc.org

IRB #17-10-419Q-02

Patients with advanced myeloid malignancies

People with myeloid leukemia are asked to participate in a research study being conducted by Albert Einstein College of Medicine.

You may be eligible to participate in this study if you:

  • Are a male or female 18 years of age or older
  • Have a diagnosis of myeloid leukemia
  • Have adequate blood clotting within the last 7 days

You may not participate in this study if you:

  • Have a history of cardiac disease
  • Have known human immunodeficiency virus (HIV)
  • Have Hepatitis B or Hepatitis C not controlled by therapy
  • Are unable to swallow oral medication
  • Are pregnant, breastfeeding or plan to become pregnant
Contact Information

Kailashben Thummar, Study Coordinator
111 E. 210th Street
Bronx, New York 10467
Phone: (718) 920-6642
Email: kthummar@montefiore.org

IRB #18-06-93-01

Focal Segmental Glomerulosclerosis

People with focal segmental glomerulosclerosis are asked to participate in a research study being conducted by New York University School of Medicine.

You may be eligible to participate in this study if you:

  • Are male or female aged 8 to 75 years old within the U.S.
  • Are male or female aged 18 to 75 years old outside of the U.S.
  • Have had biopsy-proven primary focal segmental glomerulosclerosis

You may not participate in this study if you:

  • Have FSGS secondary to another condition
  • Have a history of type 1 diabetes mellitus or uncontrolled type 2 diabetes mellitus
  • Have participated in a study of another investigational product within the past 28 days
  • Are pregnant, breastfeeding or planning to become pregnant
Contact Information

Kalliopi Grammatikopoulos, Study Coordinator
420 Lakeville Road
New Hyde Park, NY 11040
Phone: (718) 470-3499
Email: kgrammatik@northwell.edu

IRB #17-10-419Q-03

IMpassion030 (OPERABLE TRIPLE-NEGATIVE BREAST CANCER)

People with breast cancer are asked to participate in a research study being conducted by Northwell Health.

You may be eligible to participate in this study if you:

  • Are a male or female at least 18 years of age or older
  • Have been diagnosed with non-metastatic operable stage II-III breast cancer

You may not participate in this study if you:

  • Have had prior history of invasive breast cancer
  • Have active or history of autoimmune disease or immune deficiency, hepatitis B or C
  • Have had severe infections within the past 4 weeks
  • Are pregnant, breastfeeding or plan to become pregnant
Contact Information

Melissa Ramgadoo, Study Coordinator
450 Lakeville Road
Lake Success, New York 11042
Phone: (516) 734-3584
Email: MRAMGADOO@northwell.edu

IRB #18-06-203-03

Primary Focal Segmental Glomerulosclerosis (FSGS)

People with primary focal segmental glomerulosclerosis are asked to participate in a research study being conducted by Montefiore Medical Center.

You may be eligible to participate in this study if you:

  • Are a male or female at least 18 years of age or older
  • Have a diagnosis of primary focal segmental glomerulosclerosis

You may not participate in this study if you:

  • Have chronic hepatitis B or C; HIV nephropathy
  • Have any known bleeding disorders or significant active peptic ulceration
  • Have received a live vaccine within the past 6 weeks
  • Are pregnant or breastfeeding
Contact Information

Lisandra Ninonuevo Villalba, Study Coordinator
1300 Morris Park Ave, Block Bldg, Room 612
Bronx, New York 10461
Phone: (718) 798-5687
Email: lisandra.ninonuevo@einstein.yu.edu

IRB #18-02-171-01

Mild Alzheimer’s Disease

People with Alzheimer’s disease are asked to participate in a research study being conducted by New York University School of Medicine.

You may be eligible to participate in this study if you:

  • Are a male or female 50-80 years old
  • Have a gradual and progressive change in memory function over more than 6 months

You may not participate in this study if you:

  • Has a known history of human immunodeficiency virus (HIV), Hepatitis B or C
  • Have a presence of diabetes mellitus not controlled or adequately managed.
  • Have had major surgery within the last 12 weeks
  • Are pregnant, breastfeeding or planning to become pregnant
Contact Information

Jamika Singleton-Garvin, Study Coordinator
145 E. 32nd Street
New York, New York 10016
Phone: (212) 263-5708
Email: jamika.singleton-garvin@nyumc.org

IRB #17-02-441Q-02

SPI-POZ-202 non-small cell lung cancer

People with non-small cell lung cancer are asked to participate in a research study being conducted by Montefiore Medical Center.

You may be eligible to participate in this study if you:

  • Are a least 18 years of age
  • Have a histologically confirmed diagnosis of non-small cell lung cancer
  • Have had at least one prior systemic therapy for metastatic disease

You may not participate in this study if you:

  • Have a history of congestive heart failure
  • Have an active liver disease or biliary tract disease
  • Have had recent major surgery within the past 15 days
  • Are pregnant, breastfeeding or planning to become pregnant

For Study Information, search for “SPI-POZ-202” on Clinicaltrials.gov

or visit https://clinicaltrials.gov/ct2/show/NCT03318939?term=spi-poz-202&rank=1

Contact Information
Mariano Bazan, Study Coordinator
1521 Jarrett Place
Bronx, New York 10461
Phone: (718) 862-8840 Ext.436
Email: mbazan@montefiore.org

Paroxysmal Atrial Fibrillation

People with Paroxysmal Atrial Fibrillation are asked to participate in a research study being conducted by Montefiore Medical Center.

You may be eligible to participate in this study if you:

• Are a male or female at least 18 years of age or older
• Have a history of symptomatic, paroxysmal atrial fibrillation (PAF) who have had 2 or more episodes of PAF reported within the past 6 months
• Are a suitable candidate for intra-cardiac mapping and ablation of arrhythmia

You may not participate in this study if you:

• Have Atrial Fibrillation secondary to electrolyte imbalance, thyroid disease or reversible or non-cardiac cause
• Have significant restrictive or obstructive pulmonary disease or chronic respiratory condition
• Are pregnant or breastfeeding

Contact Information
Dalvert Polanco, Study Coordinator
111 East 210th Street
Bronx, NY 10467
Phone: (718) 920-6442
Email: DAPOLANC@MONTEFIORE.ORG

ADAPT Pulmonary Arterial Hypertension

People with Pulmonary Arterial Hypertension are asked to participate in a research study being conducted by North Shore University Hospital.

You may be eligible to participate in this study if you:

Are a least 18 years of age

  • Have been prescribed Orenitram, per the package insert indication, and plan to initiate therapy with this medication, or have been receiving Orenitram for 21 or fewer days
  • the ability to answer surveys and use the diary in English
  • Have access to the internet

You may not participate in this study if you:

  • Have previously received Orenitram for more than 21 days
  • Are currently receiving epoprostenol therapy or have received epoprostenol within the past 30
  • The patient is currently participating in an investigational drug or device study within the past 30 days

Contact Information
Sameer Verma, Study Coordinator
410 Lakeville Rd, Suite #107
New Hyde Park, New York 11040
Phone: (516) 465-5437
Email: sverma3@northwell.edu

 

 

Maintenance Therapy for Moderately to Severely Active Crohn’s Disease

People with Crohn’s Disease are asked to participate in a research study being conducted by Lenox Hill Hospital.

You may be eligible to participate in this study if you:

  • Are a male or female
  • Have a diagnosis of Crohn’s Disease

You may not participate in this study if you:

  • Have suspected or diagnosed intra-abdominal or perianal abscess that has not been appropriately treated
  • Have a history of uveitis (within the last year) or clinically confirmed diagnosis of macular edema
  • Have received a live vaccine within the past 4 weeks
  • Are pregnant or breastfeeding

Contact Information
Laura Durbin, Study Coordinator
100 East 77th Street
New York, New York 10075
Phone: (212) 434-3941
Email: ldurbin@northwell.edu

Maintenance Therapy for Moderately to Severely Active Crohn’s Disease

People with Crohn’s Disease are asked to participate in a research study being conducted by North Shore University Hospital.

You may be eligible to participate in this study if you:

  • Are a male or female
  • Have a diagnosis of Crohn’s Disease

You may not participate in this study if you:

  • Have suspected or diagnosed intra-abdominal or perianal abscess that has not been appropriately treated
  • Have a history of uveitis (within the last year) or clinically confirmed diagnosis of macular edema
  • Have received a live vaccine within the past 4 weeks
  • Are pregnant or breastfeeding

Contact Information
Cailin Grant, Study Coordinator
600 Northern Blvd, Suite 111
Great Neck, NY 11021
Phone: (516) 387-3912
Email: cgrant10@northwell.edu

OZANIMOD in Crohn’s Disease

People with Crohn’s Disease are asked to participate in a research study being conducted by Lenox Hill Hospital.

You may be eligible to participate in this study if you:

  • Are a male or female aged 18 to 75 years
  • Have signs and symptoms consistent with a diagnosis of Crohn’s Disease for at least 3 months

You may not participate in this study if you:

  • Have a known history of human immunodeficiency virus (HIV) infection, Hepatitis B or Hepatitis C
  • Have a history of uveitis (within the last year) or clinically confirmed diagnosis of macular edema
  • Have received a live vaccine within the past 4 weeks
  • Are pregnant or breastfeeding

Contact Information
Laura Durbin, Study Coordinator
100 E 77th Street
New York, New York 10075
Phone: (212) 434-3941
Email: LDURBIN@NORTHWELL.EDU

OZANIMOD in Crohn’s Disease

People with Crohn’s Disease are asked to participate in a research study being conducted by North Shore University Hospital.

You may be eligible to participate in this study if you:

  • Are a male or female aged 18 to 75 years
  • Have signs and symptoms consistent with a diagnosis of Crohn’s Disease for at least 3 months

You may not participate in this study if you:

  • Have a known history of human immunodeficiency virus (HIV) infection, Hepatitis B or Hepatitis C
  • Have a history of uveitis (within the last year) or clinically confirmed diagnosis of macular edema
  • Have received a live vaccine within the past 4 weeks
  • Are pregnant or breastfeeding

Contact Information
Cailin Grant, Study Coordinator
600 Northern Blvd, Suite 111
Great Neck, NY 11021
Phone: (516) 387-3912
Email: CGRANT10@NORTHWELL.EDU

Resectable Stage IIB or IIIA Non-Small Cell Lung Cancer

People with non-small cell lung cancer are asked to participate in a research study being conducted by Montefiore Medical Center.

You may be eligible to participate in this study if you:

  • Are a male or female 18 years of age or older
  • Have previously untreated, histologically confirmed non-small cell lung cancer and histologically confirmed Stage IIB or IIIA NSCLC
  • Are able to undergo protocol therapy, including necessary surgery

You may not participate in this study if you:

  • Have a known history of human immunodeficiency virus (HIV) infection, known history of Hepatitis B or known active Hepatitis C
  • Have received a live vaccine within 30 days prior to the first dose of trial drug
  • Are pregnant, breastfeeding or plan to become pregnant

Contact Information
Mariano Bazan, Study Coordinator
1521 Jarrett Place, 2nd floor
Bronx, NY 10461
Phone: (718) 862-8840 Ext. 436
Email: mbazan@montefiore.org

Resectable Stage IIB or IIIA Non-Small Cell Lung Cancer

People with non-small cell lung cancer are asked to participate in a research study being conducted by White Plains Hospital.

You may be eligible to participate in this study if you:

  • Are a male or female 18 years of age or older
  • Have previously untreated, histologically confirmed non-small cell lung cancer and histologically confirmed Stage IIB or IIIA NSCLC
  • Are able to undergo protocol therapy, including necessary surgery

You may not participate in this study if you:

  • Have a known history of human immunodeficiency virus (HIV) infection, known history of Hepatitis B or known active Hepatitis C
  • Have received a live vaccine within 30 days prior to the first dose of trial drug
  • Are pregnant, breastfeeding or plan to become pregnant

Contact Information
Joel Victor, Study Coordinator
2 Longview Avenue
White Plains, NY 10601
Phone: (914) 849-7591
Email: JVICTOR1@WPHOSPITAL.ORG

Persistent Local Esophageal Cancer

People with esophageal cancer are asked to participate in a research study being conducted by North Shore University Hospital.

You may be eligible to participate in this study if you:

  • Are a male or female 18-89 years of age
  • Have a diagnosis of esophageal cancer
  • Are not a surgical candidate or have completed or declined systemic therapy
  • Are able to tolerate an endoscopy

You may not participate in this study if you:

  • Have received radiation within the past 6 weeks
  • Have received chemotherapy within the past 2 weeks
  • Are pregnant, breastfeeding or planning to become pregnant

Contact Information

Molly Stewart, Study Coordinator
600 Community Drive
Manhasset, New York 11030
Phone: (516) 600-1443
Email: mstewart8@northwell.edu

Lung Cancer Blood Sample Study

People with suspicion of lung cancer who are scheduled for a biopsy/other diagnostic procedure are asked to participate in a research study being conducted by Long Island Jewish Medical Center.

You may be eligible to participate in this study if you:

  • Are male or female, 50-79 years of age,
  • Have a CT suspicion of lung cancer and is scheduled for biopsy or other diagnostic procedure

You may not participate in this study if you:

  • Have a prior history of cancer with the exceptions of non-melanoma skin cancer and most in-situ carcinomas
  • Have had prior removal of the lung, excluding percutaneous lung biopsy
  • Have had additional treatment or procedures for pulmonary nodules or masses prior

Contact Information
Mark Westlake, Study Coordinator
410 Lakeville Rd
New Hyde Park, New York 11040
Phone: (516) 465-5441
Email: Mwestlake@northwell.edu

Advanced Epithelial Ovarian Cancer

People with ovarian cancer are asked to participate in a research study being conducted by North Shore University Hospital.

You may be eligible to participate in this study if you:

  • Are a female at least 18 years of age or older
  • Have histologically or cytologically confirmed epithelial ovarian, fallopian tube, or peritoneal cancer
  • Had recurrent or progressive disease on or after initial platinum-based chemotherapy for the diagnosis

You may not participate in this study if you:

  • Have active diverticulitis, symptomatic peptic ulcer disease, colitis, or inflammatory bowel disease that has required treatment in the past 2 years
  • Have a known history of human immunodeficiency virus (HIV), Hepatitis B or Hepatitis C
  • Have received a live vaccine within the past 30 days
  • Are pregnant, breastfeeding or planning to become pregnant
  • Contact Information
    Ashley Hamilton, Study Coordinator
    450 Lakeville Road
    Lake Success, NY 11042
    Phone: (516) 734-8476
    Email: <a href="file:///C:/Users/cbradford1/Desktop/ahamilton3@northwell.edu

Chronic Phase Chronic Myeloid Leukemia

People with Myeloid Leukemia are asked to participate in a research study being conducted by Montefiore Medical Center.

You may be eligible to participate in this study if you:

  • Are a least 18 years of age or older at time of diagnosis
  • Have a diagnosis of Chronic Phase-Chronic Myeloid Leukemia

You may not participate in this study if you:

  • Are receiving treatment for any other prior or active non-Chronic Myeloid Leukemia active malignancy
  • Are participating in any other therapeutic clinical trial for Chronic Myeloid Leukemia disease

Contact Information
Ambar Baez, BS, Study Coordinator
111 East 210th Street, Hofheimer Room 101
Bronx, NY 10467
Phone: (718) 920-2006
Email: ambaez@montefiore.org

Patients Treated with Cholbam®/Kolbam® (Cholic Acid)

People with liver disorder are asked to participate in a research study being conducted by Montefiore Medical Center.

You may be eligible to participate in this study if you:

  • Are a male or female of any age
  • Have a diagnosis for which Cholbam/Kolbam is indicated

You may not participate in this study if you:

  • Are not be able to comply with the requirements of the protocol

Contact Information
Trang Nguyen NP, Study Coordinator
111 E. 210th Street
Bronx, New York 10467
Phone: (718) 741-2332
Email: trannguy@montefiore.org

Advanced Or Metastatic Nonsmall Cell Lung Cancer

People with Advanced or Metastatic Nonsmall Cell Lung Cancer are asked to participate in a research study being conducted by Montefiore Medical Center.

You may be eligible to participate in this study if you:

  • Are a least 18 years of age
  • Have confirmed diagnosis of unresectable Stage IIIb not amenable to treatment with combined modality chemoradiation (advanced) or Stage IV (metastatic) NSCLC
  • Have had adequate recovery from most recent systemic or local treatment for cancer

You may not participate in this study if you:

  • Are unable to swallow oral medication
  • Have known HIV positivity or AIDS-related illness
  • Are pregnant or breastfeeding

Contact Information
Mariano Bazan, Study Coordinator
1521 Jarrett Place 2nd floor
Bronx, NY 10461
Phone: (718) 862-8840 Ext.436
Email: mbazan@montefiore.org

Newly Diagnosed Glioblastoma (GBM)

People with Glioblastoma are asked to participate in a research study being conducted by Northshore University Hospital.

You may be eligible to participate in this study if you:

  • Are a male or female between 18-70 years old
  • Have confirmed diagnosis of Glioblastoma
  • Have measurable contrast enhancing disease

You may not participate in this study if you:

  • Have other uncontrolled medical conditions, e.g. myocardial infarction, cerebrovascular accident, diabetes or hypertension
  • Are unable to undergo an MRI
  • Are pregnant or breastfeeding

Contact Information

Louise Purcell, Study Coordinator
300 Community Drive
Manhasset, NY 11030
Phone: (519) 941-1263
Email: lpurcell@northwell.edu

Breast Cancer

Women with Breast Cancer are asked to participate in a research study being conducted by Montefiore Medical Center.

You may be eligible to participate in this study if you:

  • Are at least 50 years old
  • Have been diagnosed with having Breast Cancer        

 You may not participate in this study if you:

  • Have presence of luminal B pathologyHave presence of multifocal calcifications  
  • Have a ER AND PR negative, or Her 2 positive noted on pre-cryo biopsy
  • Have presence of multifocal and/or multicentric in breast cancer
  • Have presence of lobular carcinoma

Contact Information

Ameriangel Roman, Study Coordinator

1521 Jarrett Place,

Bronx, New York 10461

Email: aromaner@montefiore.org

Phone 718-862-8840 x426

 

MANAGE-HF heart failure

People with heart failure are asked to participate in a research study being conducted by Montefiore Medical Center. The MANAGE-HF study intends to evaluate whether proper clinical integration of HeartLogic, a remote monitoring diagnostic feature in Boston Scientific ICDs and CRT-Ds, can reduce heart failure hospitalization or other heart failure related events.

You may be eligible to participate in this study if you:

  • Are a least 18 years of age
  • Are implanted with an CRT-D or ICD device that has HeartLogic
  • Have current symptomatic heart failure or NYHA Class II or III

You may not participate in this study if you:

  • Are scheduled to receive a heart transplant or ventricular assist device within the next 6 months
  • Have symptomatic heart failure at rest or NYHA Class IV at time of enrollment
  • Are pregnant, breastfeeding or plan to become pregnant

Contact Information

Johanna Oviedo, Study Coordinator

3400 Bainbridge Avenue 7TH Floor

Bronx, NY 10467

Phone: (718) 920-8780

Email: joviedo@montefiore.org

GammaCore Patient Registry (GPR) Cluster Headaches

People with Cluster Headaches are asked to participate in a registry being conducted by Montefiore Medical Center.

You may be eligible to participate in this registry if you:

  • Are a least 18 years of age
  • Have been diagnosed with episodic cluster headache in accordance with the ICHD-3 criteria

There will be no exclusion criteria for participation in GPR.

Contact Information

Daniel Sun, Study Coordinator

1250 Waters Place – Tower 2

Bronx, NY 10461

Phone: (929) 263-3831

Email: dansun@montefiore.org

Breast Cancer MonarchE

People with Breast Cancer are asked to participate in a research study being conducted by White Plains Hospital.

You may be eligible to participate in this study if you:

  • Are a male or female at least 18 years of age
  • Have confirmed diagnosis of HR+, HER2-negative (HER2-), early stage resected invasive breast cancer
  • Have undergone definitive surgical treatment for the current malignancy
  • Are able to swallow oral medications

You may not participate in this study if you:

  • Have Stage IV (M1), Stage IA, and lymph node-negative breast cancer
  • Have previously received treatment with any CDK4 and CDK6 inhibitor
  • Have had surgery within the past 14 days
  • Are pregnant or breastfeeding

Contact Information

Joel Victor, Study Coordinator

2 Longview Avenue, 6th Floor, White Plains, NY 10601

Phone: 914-849-7691

Email: jvictor1@wphospital.org

Hematological Malignancies

People with Hematological Malignancies are asked to participate in a research study being conducted by Albert Einstein College of Medicine.

You may be eligible to participate in this study if you:

  • Are a male or female and are at least 18 years old
  • Are able and willing to provide bone marrow biopsies/aspirates as requested by the protocol
  • Have adequate liver function

You may not participate in this study if you:

  •  Have had major surgery in the past month
  • Are HIV positive
  • Have Hepatitis or any liver disease
  • Are currently on dialysis
  • Have had an organ transplant, with the exception of bone marrow
  • Have a planned radiation therapy

 

Contact Information

Apoorva G. Talanki

Research Coordinator

Cancer Clinical Trials

Montefiore Medical Center

1695 Eastchester Road, Second Floor

Bronx, NY 10461

718-405-8545 Office

718-405-8230 Fax

Advanced Solid Tumors

People with Advanced Solid Tumors are asked to participate in a research study being conducted by Montefiore Medical Center.

You may be eligible to participate in this study if you:

  • Are a least 18 years of age
  • Have a diagnosis of melanoma or non small cell lung cancer

You may not participate in this study if you:

  • Have known uncontrolled central nervous system (CNS) metastases and/or carcinomatous meningitis
  • Have a known additional malignancy that progressed or required active treatment within the last 2 years
  • Have a known history of human immunodeficiency virus (HIV) infection or HIV 1/2 antibodies
  • Have a history of interstitial lung disease
  • Are pregnant or breastfeeding

Contact Information

Elizabeth Paljevic, Study Coordinator

1521 Jarrett Place, 2nd Floor

Bronx, NY 10461

Phone: (718) 862-8840 Ext.443

Email: elpaljev@montefiore.org

Chronic Lymphocytic Leukemia (CLL)

People with Chronic Lymphocytic Leukemia are asked to participate in a research study being conducted by Long Island Jewish Medical Center.

You may be eligible to participate in this study if you:

 

  • Are male or female at least 18 years of age
  • Have a confirmed diagnosis of Chronic Lymphocytic Leukemia
  • Are able to swallow and retain oral medication

You may not participate in this study if you:

  • Have had prior treatment with study drug (TGR-1202)
  • Have had prior autologous stem cell transplant within the last 3 months
  • Have evidence of chronic active Hepatitis B, Hepatitis C or known history of HIV
  • Have evidence of ongoing systemic bacterial, fungal or viral infection, except localized fungal infection of skin/nails
  • Are a woman who is pregnant or lactating

Contact Information

Alexis Mark, Study Coordinator

410 Lakeville Road

New Hyde Park, New York 11042

Phone: (718) 470-4743

Email: Amark1@northwell.edu

Diffuse Large B Cell/Non-Hodgkin Lymphoma

People with Diffuse Large B Cell or Non-Hodgkin Lymphoma are asked to participate in a research study being conducted by Montefiore Medical Center.

You may be eligible to participate in this study if you:

  • Are male or female and are 18 years of age or older
  • Have confirmed diagnosis of B Cell Lymphoma, follicular lymphoma (FL), small lymphocytic lymphoma (SLL), or marginal zone lymphoma (MZL)
  • Have had prior treatment with one or more lines of standard therapy

You may not participate in this study if you:

 

  • Have a known history of Central Nervous System (CNS) lymphoma
  • Have received cancer therapy (i.e., chemotherapy, radiation therapy, immunotherapy, biologic therapy, hormonal therapy, surgery and/or tumor embolization) or any investigational drug within the past 21 days
  • Have received autologous hematologic stem cell transplant within 6 months

 

Contact Information

Ambar Baez, Study Coordinator

111 E. 210th Street

Bronx, New York 10467

Phone: (718) 920-2006

Email: ambaez@montefiore.org

Myelofibrosis

People with Myelofibrosis are asked to participate in a research study being conducted by Montefiore Medical Center.

You may be eligible to participate in this study if you:

  • Are a man or woman, age 18 years or older
  • Have a diagnosis of Myelofibrosis
  • Have evidence of inadequate response to ruxolitinib

You may not participate in this study if you:

  • Have used any other investigational agent within the past 6 months
  • Have a known human immunodeficiency virus (HIV), Hepatitis B or Hepatitis C
  • Have uncontrolled, severe, or unstable cardiac disease
  • Are pregnant, breastfeeding or plan to become pregnant

 

Contact Information

Savita Bhutoria

Study Coordinator

Division of Hematology

921 Ullman,

Albert Einstein College of Medicine

Phone: 718-430-8839

Fax:718-430-8855

HPV 16/HPV18

Women with HPV are asked to participate in a research study being conducted by Montefiore Medical Center.

You may be eligible to participate in this study if you:

  • Are a female aged 18 or older
  • Have confirmed vulvar infection with HPV types 16 and/or 18 (confirmation test performed on study)
  • Have a normal screening electrocardiogram (ECG)

You may not participate in this study if you:

  • Have untreated microinvasive or invasive cancer
  • Have had treatment for genital warts within the past 4 weeks
  • Are pregnant, breastfeeding or are considering becoming pregnant within 6 months

Contact Information
Arisa Kapedani, Study Coordinator
111 E. 210th Street
Bronx, New York 10467
Phone: (718) 696-4202

Email: akapedan@montefiore.org

Advanced or Metastatic Solid Tumors

People with solid tumors are asked to participate in a research study being conducted by Montefiore Medical Center

You may be eligible to participate in this study if you:
• Are at least 18 years old
• Have malignancies in the advanced or metastatic stage
• Are able to swallow whole capsules
• Have the willingness and ability to comply with all protocol-specified requirements

You may not participate in this study if you:
• Have received chemotherapy, biologic therapy, immunotherapy or any other investigational agent within the past 3 weeks
• Have a known hypersensitivity to any temozolomide component or to dacarbazine (DTIC)
• Have had any major surgical procedure, open biopsy or traumatic injury within the past 4 weeks
• Have an active infection requiring systemic treatment
• Are pregnant, breastfeeding or plan to become pregnant

Contact Information

Mohammad Ghalib, Study Coordinator

1695 Eastchester Road

Bronx New York, 10461

Phone:  (718) 405.8515

Email: mhghalib@montefiore.org

Solid Tumors

People with solid tumors are asked to participate in a research study being conducted by Icahn School of Medicine at Mount Sinai

You may be eligible to participate in this study if you:

  • Are at least 18 years old
  • Have malignancies in the advanced or metastatic stage
  • Are able to swallow whole capsules
  • Have the willingness and ability to comply with all protocol-specified requirements

You may not participate in this study if you:

  •  Have received chemotherapy, biologic therapy, immunotherapy or any other investigational agent within the past 3 weeks
  • Have a known hypersensitivity to any temozolomide component or to dacarbazine (DTIC)
  • Have had any major surgical procedure, open biopsy or traumatic injury within the past 4 weeks
  • Have an active infection requiring systemic treatment
  • Are pregnant, breastfeeding or plan to become pregnant

Contact Information

Jean Hum, Study Coordinator

17 East 102nd Street

New York, New York 10029

Phone: (212) 824-7312

Email: jean.hum@mssm.edu

Efficacy and Safety of Dysport® (AbobotulinumtoxinA) in Pediatric Lower Limb Spasticity

People with Pediatric Lower Limb Spasticity are being asked to participate in a research study being conducted by Montefiore Medical Center.

You may be eligible to participate in this study if your child:

  • Is a female or male aged 2 to 17 years old
  • Has primary diagnosis of PLL spasticity and either previously untreated with abotulinum neurotoxin (BoNT) or previously treated with BoNT

 

You may not participate in this study if your child:

  • Has known resistance to any BoNT or experienced serious safety issues with previous use of BoNT
  • Has had previous treatment with aminoglycoside antibiotics within the last 30 days
  • Has a current need for surgery in the lower limb
  • Is pregnant and/or a lactating female

Contact Information

Beendu Pujar, Study Coordinator

111 E. 210th Street

Bronx, New York 10467

Phone: (718) 920-4321

Email: bpujar@montefiore.org

Breast Cancer

Women with Breast Cancer are asked to participate in a research study being conducted by Montefiore Medical Center.

You may be eligible to participate in this study if you:

  • Are at least 60 years old
  • Have been diagnosed with having Breast Cancer

You may not participate in this study if you:

  • Have presence of luminal B pathologyHave presence of multifocal calcifications
  • Have a ER AND PR negative, or Her 2 positive noted on pre-cryo biopsy
  • Have presence of multifocal and/or multicentric in breast cancer
  • Have presence of lobular carcinoma

Contact Information

Prena Etchen, Study Coordinator

111 East 210th Street, Bronx, New York 10467

Phone (718) 798-5687

Email: pzagreda@montefiore.org

 

Breast Cancer

People with Breast Cancer are asked to participate in a research study being conducted by Montefiore Medical Center.

You may be eligible to participate in this study if you:

  • Are a female or male and are at least 18 years old
  • Have been diagnosed with having Breast cancer

You may not participate in this study if you:

  • Have stage IV breast cancerAre currently pregnant or lactating
  • Have any allergies or are hypersensitive to the components of the atezolizumab formulation
  • Have bilateral breast cancer
  • Have a history of an autoimmune disease or immune deficiency, including but not limited to: myasthenia gravis, myositis, autoimmune hepatitis, systemic lupus erythematosus, rheumatoid arthritis, inflammatory bowel disease, antiphospholipid syndrome, Wegener granulomatosis, Sjögren syndrome, Guillain-Barré syndrome, or multiple sclerosis
  •  Are HIV positive
  • Currently have tuberculosis
  • Have had a major surgery within the past month

Contact Information

Lisa Escobar-Peralta, Study Coordinator

1521 Jarret Place, 2nd Floor Bronx, NY 10461

Phone (718) 379-6866

Email: lescobar@montefiore.org

Breast Fibroadenoma

Women with Breast Fibroadenoma are asked to participate in a research study being conducted by Montefiore Medical Center.

You may be eligible to participate in this study if you:

  • Are at least 18 years old
  • Have been diagnosed with having fibroadenoma’s in the breast and currently have at least one fibroadenoma in the breast

You may not participate in this study if you:

  • Have calcified fibroadenoma’s in your breast
  • Have a history of breast cancer
  • Have breast implants
  • Have participated in another investigational drug or device study

Contact Information

Prena Etchen, Study Coordinator

111 East 210th Street, Bronx, New York 10467

Phone (718) 798-5687

Email: pzagreda@montefiore.org

 

Hepatocellular Carcinoma

People who have Hepatocellular Carcinoma (HCC) are asked to participate in a research study being conducted by North Shore University Hospital

You may be eligible to participate in this study if you:

  • Are a male or female, at least 18 years or older
  • Have a diagnosis of Hepatocellular Carcinoma (HCC)

You may not participate in this study if you:

  • Have the inability of providing a written informed consent

Contact Information

Radica Palmer, Study Coordinator

400 Community Drive Manhasset, NY 11030

Phone: (516) 562-2082

Fax: (516) 562-4563

Email: RPalmer@northwell.edu

Advanced Malignancies

People with Advanced Malignancies are asked to participate in a research study being conducted by Montefiore Medical Center.

You may be eligible to participate in this study if you:

  • Are male or female and are at least 18 years old
  • Have confirmed solid tumors or lymphoma

You may not participate in this study if you:

  • Have had extensive radiotherapy within the past two years
  • Are HIV positive Have had any major surgery within the past month 
  • Are a female and are currently lactating or pregnant
  • Have Hepatitis B or C
  • Have any allergies to the study drug

Contact Information

Elizabeth Paljevic, Study Coordinator

111 E. 210th Street Bronx, NY 10467

Phone (718) 862-8840 Ext. 443

Email: elpaljev@montefiore.org

 

Blood or Bone Marrow Cancer

People with  blood or bone marrow cancer asked to participate in a research study being conducted by Icahn School of Medicine at Mount Sinai

You may be eligible to participate in this study if you:

  • Are a Male or female between 18 and 60 years of age
  • Have a diagnosis of blood or bone marrow cancer

You may not participate in this study if you:

  • Have active cytomegalovirus (CMV) colitis
  • Have chronic hepatitis B (HBV) or hepatitis C (HCV) infection
  • Have evidence of an active systemic infection during Screening
  • Have received a prior allogeneic transplant

Contact Information

Christine Woo, Study Coordinator

One Gustave L. Levy Place

New York, New York 10029

Phone: (212) 241-0691

Fax: (212) 241-8618

Email: christine.woo@mssm.edu

 

Bladder Cancer/BOND 2

People with non-muscle invasive bladder cancer are asked to participate in a research study being conducted by Montefiore Medical Center

You may be eligible to participate in this study if you:

  • Are at least 18 years of age or older
  • Have a diagnosis of non-muscle invasive bladder cancer
  • Were previously treated with BCG

You may not participate in this study if you:

  • Have known infection with HIV, HBV or HCV
  • Have systemic treatment on any investigational clinical trial within 28 days prior to registration
  • Have a history of prior experimental cancer vaccine treatment (e.g.,dendritic cell therapy, heat shock vaccine) within the last year
  • Progressive or persistent viral or bacterial infection

Contact Information

JoAnn M. Horn, Study Coordinator

1250 Waters Place, Tower One, Suite 706

Bronx, NY 10461

Phone: (347) 842-1715

Fax: (917) 962-5410

Email: johor@montefiore.org

 

Lung Neuroendocrine Tumors

People with well-differentiated metatatic and/or unresectable typical or atypical lung neuroendocrine tumors are asked to participate in a research study being conducted by Montefiore Medical Center

You may be eligible to participate in this study if you:

  • Are at least 18 years
  • Have a diagnosis of well-differentiated metatatic and/or unresectable typical or atypical lung neuroendocrine tumors

You may not participate in this study if you:

  • Had surgery within 6 weeks
  • Are pregnant or breastfeeding

Contact Information

Alexandra Urman, Study Coordinator

1521 Jarret Place, Bronx, NY 10461

Phone: (718) 379-6868

Email: aurman@montefiore.org

Inflammatory Bowel Disease – Minors 17 and younger

Children with inflammatory bowel disease are asked to participate in a research study being conducted by Schneider Children’s Hospital.

You may be eligible to participate in this study if you:

  • Are a minor 17 years or younger
  • Have been diagnosed with inflammatory bowel disease for at least 2 months

You may not participate in this study if you:

  • Have other Crohn’s-like diseases that are associated with genetic diseases (eg, glycogen storage disease)
  • Have participated in another research study within the last 30 days

 

Contact Information

Kathy Grancher, Study Coordinator

Schneider Children’s Hospital

269-01 76th Avenue

Suite 234

New Hyde Park, NY 11040

Phone: 718-470-3363

Fax: 718-962-2908

Email: kgranche@nshs.edu

 

 

Juvenile Idiopathic Arthritis (JIA) – Minors

Parents with children with Juvenile Idiopathic Arthritis (JIA) are asked to participate in a research study being conducted by Schneider Children’s Hospital.

Your child may be eligible to participate in this study if your child:

  • Is 4 to 17 years old
  • Has been diagnosed with JIA
  • Is taking Humira® or MTX therapy

Your child may not participate in this study if your child:

  • Cannot be treated with Huira®
  • Has been treated with any approved or experimental drug such as etanercept (Enbrel®), abatacept (Orencia®), infliximab (Remicade®) or rituximab (Rituxan®).
  • Has participated in another research study within the last 30 days

Contact Information

Marilynn Orlando, Study Coordinator

Schneider Children’s Hospital

269-01 76 Avenue

New Hyde Park, NY 11040

Phone: 718-470-3530

Fax: 718-831-0182

Email: Morlando@lij.edu

 

 

Diamond Blackfan Anemia – Adults

Adults with Diamond Blackfan Anemia and are currently receiving red blood cell transfusion therapy, are asked to participate in a research study being conducted by Cohen Children’s Medical Center of New York.

You may be eligible to participate in this study if you:

  • Are 18 years old or older
  • Have been diagnosed with Diamond Blackfan anemia
  • Are currently receiving red blood cell transfusion therapy

You may not participate in this study if you:

  • Have a history of hypertension.
  • Are a pregnant or lactating female
  • Have received another investigational drug or device within the past 2 months

Contact Information

Ellen Muir, RN, MSN, CNS, Study Coordinators

Cohen Children’s Medical Center of New York

269-01 76th Avenue, Room 255

New Hyde Park, New York 11040

Phone: (516) 562-1505

Fax: (516) 562-1599

Email: emuir@nshs.edu

 

Chronic Obstructive Pulmonary Disease (COPD)

Adults with Chronic Obstructive Pulmonary Disease (COPD) and a history of or at risk for cardiovascular disease are asked to participate in a research study being conducted by NJ Heart.
You may be eligible to participate in this study if you:

  • Are 40 to 80 years old
  • Have a confirmed diagnosis (that meets study requirements)

You may not participate in this study if you:

  • Are a woman who is pregnant or breast feeding
  • Are known or suspected to have a history of alcohol or drug abuse within the last 2 years

Research conducted at:
NJ Heart
520 North Wood Avenue
Linden, NJ 07036
Contact Information
Srilakshmi Kuchipudi
Email: skuchipudi@njheart.net