Virtual Pooled Registry Cancer Linkage System/BRANY Central IRB
NIH NCI Registry Operations
Virtual Pooled Registry Cancer Linkage System
Statistics
| Number of expedited reviews complete | 23 |
| Expedited Review TAT* | 3.17 |
| Number of exempt determinations completed | 4 |
| Exempt determination TAT* | 3.25 |
| Number of Modifications | 9 |
| Modifications TAT* | 3.56 |
* TAT (turnaround time) = average # of business days from submission receipt to IRB approval
States/Registries relying on BRANY IRB:
- California
- Connecticut
- Georgia
- Hawaii
- Maine
- Maryland
- Michigan
- New Jersey
- New Mexico
- North Dakota
- Oklahoma
- Oregon
- Puerto Rico
- Rhode Island
- Tennessee
- Texas
- Virginia
- Wyoming
BRANY IRB is contracted with National Cancer Institute (NCI) to serve as a Central IRB to review Virtual Pooled Registry – Cancer Linkage System (VPR–CLS) studies. The Common Rule requires use of a Central (or single) IRB for cooperative research. Reliance on a Central IRB can eliminate redundancy and provide a consistent, high quality, expert review process that protects privacy and confidentiality while saving time and resources.
To streamline the Central IRB application and review process for VPR-CLS studies, the North American Association of Central Cancer Registries (NAACCR) has developed a Templated IRB/Registry Application (TIRA -common form). BRANY IRB will perform their review using the TIRA and other supporting documents submitted with the VPR-CLS request.
The flow diagram below outlines the process for submitting to NAACCR and BRANY IRB.
VPR-CLS Central IRB Submission Guidelines
Recent Presentations
- BRANY IRB as Central IRB for Review of VPR-CLS Linkage Requests: Purpose, Progress and Plans for 2022
- Streamlining the IRB Process
IRBManager™ (One Aegis) Getting Started
- New users: Go to the login screen. Use the Click here to register link to enable your account.
- IRBManager™ & xForms Basics Webinar
- Live webinar on the 1stTuesday of the month.
- To register, log into the portal. Download the calendar invite under BRANY Notices.
IRB Membership List — Compliance Statement
- IRB Membership List (Current)
- BRANY IRB Compliance Statement
- BRANY IRB Registration
BRANY IRB is registered per 45 CFR 46 Subpart E and 21 CFR 56.106 (Registration #IRB00000080 and #IRB00010793)
Reporting Timelines
Reporting Timelines
| UPIRTSOS (Unanticipated Problems) | Report per occurrence within 5 days |
| Serious Adverse Events (Local) | Report per occurrence within 5 days |
| Unanticipated Adverse Device Events (UADEs) | Report per occurrence within 10 days |
| Complaints | Report per occurrence within 5 days |
| Major Deviations | Report per occurrence within 10 days |
| Minor Deviations | Report in aggregate with continuing review or study closure |